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Hebei yanxi chemical co.,LTD.

Hebei yanxi chemical co.,LTD.., who registered capital of 10 million yuan, nearly to $2 million, we have a pharmaceutical raw materials factory production of pharmaceutical raw materials, and a reagent r&d center, and we do research and develop

2,2,2-TrifluoroethylaMine hydrochloride

Cas:373-88-6

Min.Order:5 Kilogram

FOB Price: $170.0 / 200.0

Type:Trading Company

inquiry

Dayang Chem (Hangzhou) Co.,Ltd.

DayangChem exported this product to many countries and regions at best price. If you are looking for the material's manufacturer or supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product spe

2,2,2-Trifluoroethylamine hydrochloride Manufacturer/High quality/Best price/In stock

Cas:373-88-6

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Wuhan Fortuna Chemical Co.,Ltd

Manufacturer supply 2,2,2-Trifluoroethylamine hydrochloride CAS 373-88-6 with attractive price Company profile Wuhan Fortuna Chemical Co.,Ltd established in 2006, is a big integrative chemical enterprise being engaged in Pharmaceutical & its

Manufacturer supply 2,2,2-Trifluoroethylamine hydrochloride CAS 373-88-6 with attractive price

Cas:373-88-6

Min.Order:10 Kilogram

FOB Price: $10.0

Type:Trading Company

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Henan Allgreen Chemical Co.,Ltd

high quality Appearance:white powder Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea Port:shanghai

2,2,2-TrifluoroethylaMine Hydrochloride

Cas:373-88-6

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply 2,2,2-trifluoroethylamine hydrochloride

Cas:373-88-6

Min.Order:1

Negotiable

Type:Other

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

2,2,2-Trifluoroethylamine hydrochloride

Cas:373-88-6

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Henan Tianfu Chemical Co., Ltd.

TIANFUCHEM--373-88-6--High purity 2,2,2-Trifluoroethylamine hydrochloride factory price Our company was built in 2009 with an ISO certificate.In the past 10 years, we have grown up as a famous fine chemicals supplier in China And we had es

TIANFUCHEM--373-88-6--High purity 2,2,2-Trifluoroethylamine hydrochloride factory price

Cas:373-88-6

Min.Order:1 Metric Ton

FOB Price: $2000.0

Type:Lab/Research institutions

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Top Purity CAS 373-88-6 with fast shipping

Cas:373-88-6

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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LIDE PHARMACEUTICALS LIMITED

Advantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the R&amp

2,2,2-Trifluoroethylamine hydrochloride/ LIDE PHARMA- Factory supply / Best price

Cas:373-88-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Henan Sinotech Import&Export Corporation

Product Name 2,2,2-Trifluoroethylamine hydrochloride Synonyms 2,2,2-Trifluoroethyla;2,2,2-trifluoroethan-1-aMine chloride;2,2,2-TrifluoroethylaMine Hydrochloride, 97+%;TAF;TRIFLUOROETHYLAMINE HYDROCHLORI

2,2,2-Trifluoroethylamine hydrochloride CAS: 373-88-6

Cas:373-88-6

Min.Order:5 Metric Ton

FOB Price: $1.0 / 2.0

Type:Other

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

2,2,2-Trifluoroethylamine hydrochloride 373-88-6

Cas:373-88-6

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At presen

2,2,2-Trifluoroethylamine hydrochloride

Cas:373-88-6

Min.Order:1 Gram

FOB Price: $12.0 / 13.0

Type:Trading Company

inquiry

Qingdao Beluga Import and Export Co., LTD

2,2,2-Trifluoroethylamine hydrochloride CAS:373-88-6 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high qua

2,2,2-Trifluoroethylamine hydrochloride CAS:373-88-6

Cas:373-88-6

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

CAS NO.:373-88-6

Cas:373-88-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Changchun Artel lmport and Export trade company

Product Detail Minimum Order Qty. 10 Gram

2,2,2-Trifluoroethylamine hydrochloride 99.2%, CAS: 373-88-6, good price CAS NO.373-88-6

Cas:373-88-6

Min.Order:10 Gram

Negotiable

Type:Trading Company

inquiry

Henan Kanbei Chemical Co.,LTD

1. Well-equipped, stable and high-quality raw material supply chain, to provide customers with the best quality products. 2.Strict quality inspection process and professional certificate testing to ensure the quality level of the final product. 3.E

hot sale 2,2,2-TrifluoroethylaMine hydrochloride

Cas:373-88-6

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

2,2,2-Trifluoroethylamine hydrochloride

Cas:373-88-6

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

2,2,2-Trifluoroethylamine hydrochloride

Cas:373-88-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

SHANGHAI T&W PHARMACEUTICAL CO., LTD.

A substitute for perfluorooctanoic acid, mainly used as a surfactant, dispersant, additive, etc Appearance:White solid or Colorless liquid Purity:99.3 % We will ship the goods in a timely manner as required We can provide relevant documents acc

2,2,2-trifluoroethan-1-amine hydrochloride

Cas:373-88-6

Min.Order:4 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Massive Chemical Technology Co., Ltd.

Massive Chemical is certified with ISO9001 and ISO14001 manufacturer for this product. We will offer all documents as requirement for the materials which includes, Certificate of Analysis, Material Safety Data Sheet, and Method of Analysis and

2,2,2-Trifluoroethylamine hydrochloride

Cas:373-88-6

Min.Order:1 Gram

FOB Price: $1.0

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

2,2,2-TrifluoroethylaMine Hydrochloride

Cas:373-88-6

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

Hangzhou Lingrui Chemical Co.,Ltd.

2,2,2-TrifluoroethylaMine hydrochlorideAppearance:detailed see specifications Storage:Store in dry, dark and ventilated place. Package:according to customers' requirements Application:It is an important intermediate used in Organic Synthesis, Pharmac

2,2,2-TrifluoroethylaMine hydrochloride

Cas:373-88-6

Min.Order:1 Gram

Negotiable

Type:Other

inquiry

HANGZHOU YUNUO CHEMICAL CO.,LTD

Superior quality Appearance:WHITE TO LIGHT YELLOW CRYSTALLINE POWDER Storage:Stored in cool, dry and ventilation place; Away from fire and heat Package:1kg/bag, 1kg/drum or 25kg/drum or as per your request. Application:Used as Pharmaceutical Interm

2,2,2-Trifluoroethylamine hydrochloride

Cas:373-88-6

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Siwei Development Group Ltd.

Product name: 2,2,2-Trifluoroethylamine Hydrochloride CAS No.:373-88-6 Molecule Formula:C2H5ClF3N Molecule Weight:100.06 Purity: 98.0% Package: 25kg/drum Description:White powder Manufacture Standards:Enterprise Standard

High Quality 2,2,2-Trifluoroethylamine Hydrochloride

Cas:373-88-6

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Zibo Dorne chemical technology co. LTD

Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,

2,2,2-Trifluoroethylamine hydrochloride

Cas:373-88-6

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Minstar Chemical Co., Ltd

Product Name: 2,2,2-Trifluoroethylamine hydrochloride Synonyms: 2,2,2-Trifluoroethyla;2,2,2-trifluoroethan-1-aMine chloride;2,2,2-trifluoroethanaminium chloride;2,2,2-TrifluoroethylaMine Hydrochloride, 97+%;TAF;TRIFLUOROETHYLAMINE HYDROCHLORIDE

2,2,2-Trifluoroethylamine Hydrochloride 373-88-6 C2H5ClF3N

Cas:373-88-6

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

TAIZHOU ZHENYU BIOTECHNOLOGY CO., LTD

Zhenyu biotech exported this product to many countries and regions at best price. if you are looking for the material's manufacturer or supplier in china, zhenyu biotech is your best choice. pls contact with us freely for getting detailed

2,2,2-Trifluoroethylamine hydrochloride

Cas:373-88-6

Min.Order:1 Kilogram

FOB Price: $2.0

Type:Lab/Research institutions

inquiry

Wuhu Nuowei Chemistry Technologies Co., Ltd.

Wuhu Nuovo Chemical Technology Co., Ltd. was established in August 2014, mainly engaged in the development, production and sales of ionic liquids, ribose, nucleosides, nucleotides and related chemicals; Products are mainly used in new energy, new ma

2,2,2-Trifluoroethylamine hydrochloride

Cas:373-88-6

Min.Order:100 Gram

Negotiable

Type:Manufacturers

inquiry

Hunan chemfish Pharmaceutical co.,Ltd

Appearance:95%+ Package:R&D,Pilot run Transportation:per client require Port:Express ,Air, Sea

2,2,2-Trifluoroethylaminehydrochloride

Cas:373-88-6

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Chemlyte Solutions

Chemlyte Solutions believe that customers and suppliers deserve much more than what traditional distributors can offer. To grow in today s fast-paced and increasingly competitive market it is essential to be able to quickly adapt to market forces eff

2,2,2-Trifluoroethylamine hydrochloride

Cas:373-88-6

Min.Order:100 Gram

Negotiable

Type:Other

inquiry

Synthetic route

trifluoroethylamine
753-90-2

trifluoroethylamine

2,2,2-trifluroethylamine hydrochloride
373-88-6

2,2,2-trifluroethylamine hydrochloride

Conditions
ConditionsYield
With hydrogenchloride In ethanol; water at 25 - 50℃; for 1h; Temperature;96.3%
benzylamine
100-46-9

benzylamine

trifluoroacetic acid
76-05-1

trifluoroacetic acid

2,2,2-trifluroethylamine hydrochloride
373-88-6

2,2,2-trifluroethylamine hydrochloride

Conditions
ConditionsYield
Stage #1: benzylamine; trifluoroacetic acid With tetrachloromethane; TEA; triphenylphosphine In chloroform at 80℃; for 0.666667h;
Stage #2: With TEA; water at 80℃; for 12h;
Stage #3: With hydrogenchloride In methanol for 12h; Heating;
94%
[1-Phenyl-meth-(E)-ylidene]-(2,2,2-trifluoro-ethyl)-amine

[1-Phenyl-meth-(E)-ylidene]-(2,2,2-trifluoro-ethyl)-amine

2,2,2-trifluroethylamine hydrochloride
373-88-6

2,2,2-trifluroethylamine hydrochloride

Conditions
ConditionsYield
With hydrogenchloride In diethyl ether for 4h; Ambient temperature;87%
N-(2,2,2-trifluoroethyl)benzamide
348-08-3

N-(2,2,2-trifluoroethyl)benzamide

2,2,2-trifluroethylamine hydrochloride
373-88-6

2,2,2-trifluroethylamine hydrochloride

Conditions
ConditionsYield
With hydrogenchloride In methanol for 24h; Heating;
1-benzyl-1H-pyrrole-2,5-dione
1631-26-1

1-benzyl-1H-pyrrole-2,5-dione

2,2,2-trifluroethylamine hydrochloride
373-88-6

2,2,2-trifluroethylamine hydrochloride

3a,6a-dihydro-5-(phenylmethyl)-3-(trifluoromethyl)pyrrolo[3,4-c]pyrazole-4,6(1H,5H)-dione
1428147-22-1

3a,6a-dihydro-5-(phenylmethyl)-3-(trifluoromethyl)pyrrolo[3,4-c]pyrazole-4,6(1H,5H)-dione

Conditions
ConditionsYield
Stage #1: 2,2,2-trifluroethylamine hydrochloride With sodium nitrite In dodecane; water Inert atmosphere;
Stage #2: 1-benzyl-1H-pyrrole-2,5-dione In diethyl ether at 20℃; Inert atmosphere;
100%
3-pyridinecarboxaldehyde
500-22-1

3-pyridinecarboxaldehyde

2,2,2-trifluroethylamine hydrochloride
373-88-6

2,2,2-trifluroethylamine hydrochloride

(pyridine-3-ylmethylene)(2,2,2-trifluoroethyl)amine
1424799-68-7

(pyridine-3-ylmethylene)(2,2,2-trifluoroethyl)amine

Conditions
ConditionsYield
With sodium hydroxide In water; toluene at 20℃; Cooling with ice;100%
With triethylamine In acetonitrile at 0 - 20℃; for 15h;84%
2,2,2-trifluroethylamine hydrochloride
373-88-6

2,2,2-trifluroethylamine hydrochloride

1H-pyrazole-4-carbaldehyde
35344-95-7

1H-pyrazole-4-carbaldehyde

(1H-pyrazol-4-ylmethylene)(2,2,2-trifluoroethyl)amine
1424799-64-3

(1H-pyrazol-4-ylmethylene)(2,2,2-trifluoroethyl)amine

Conditions
ConditionsYield
With sodium hydroxide In water; toluene at 20℃; Cooling with ice;100%
2,2,2-trifluroethylamine hydrochloride
373-88-6

2,2,2-trifluroethylamine hydrochloride

chloroacetyl chloride
79-04-9

chloroacetyl chloride

2-chloro-N-(2,2,2-trifluoroethyl)acetamide
170655-44-4

2-chloro-N-(2,2,2-trifluoroethyl)acetamide

Conditions
ConditionsYield
Stage #1: 2,2,2-trifluroethylamine hydrochloride With tert-butyl methyl ether; sodium hydroxide In water at 20℃; for 0.5h;
Stage #2: chloroacetyl chloride at 5 - 10℃; for 1h;
100%
With potassium carbonate In dichloromethane; water at 0 - 30℃; for 3.16667h;87.2%
Stage #1: 2,2,2-trifluroethylamine hydrochloride With sodium hydroxide In tert-butyl methyl ether; water at 0℃; for 0.5h;
Stage #2: chloroacetyl chloride In tert-butyl methyl ether; water at 0℃; for 1h;
63%
Stage #1: 2,2,2-trifluroethylamine hydrochloride With sodium hydroxide In tert-butyl methyl ether; water at 0 - 5℃; for 0.5h;
Stage #2: chloroacetyl chloride In tert-butyl methyl ether; water at 5 - 10℃; for 1h;
1-ethenyl-4-methylbenzene
622-97-9

1-ethenyl-4-methylbenzene

2,2,2-trifluroethylamine hydrochloride
373-88-6

2,2,2-trifluroethylamine hydrochloride

(+/-)-1-methyl-4-((trans)-2-(trifluoromethyl)cyclopropyl)benzene

(+/-)-1-methyl-4-((trans)-2-(trifluoromethyl)cyclopropyl)benzene

Conditions
ConditionsYield
With dmap; meso-tetraphenylporphyrin iron(III) chloride; sulfuric acid; sodium acetate; sodium nitrite In water at 20℃; for 14.0167h; Inert atmosphere; diastereoselective reaction;99%
With dmap; meso-tetraphenylporphyrin iron(III) chloride; sulfuric acid; sodium acetate; sodium nitrite In water for 14h; Inert atmosphere;
2,2,2-trifluroethylamine hydrochloride
373-88-6

2,2,2-trifluroethylamine hydrochloride

propynoic acid methyl ester
922-67-8

propynoic acid methyl ester

3-trifluoromethyl-1H-pyrazole-5-carboxylic acid methyl ester
6833-82-5

3-trifluoromethyl-1H-pyrazole-5-carboxylic acid methyl ester

Conditions
ConditionsYield
With sodium nitrite In dichloromethane; water at 0 - 20℃; for 24h;99%
With sodium nitrite In dichloromethane; water at 20℃; for 72h;
With sodium nitrite In dichloromethane; water at 0 - 20℃;
1-phenylbut-3-yn-2-one
31739-46-5

1-phenylbut-3-yn-2-one

2,2,2-trifluroethylamine hydrochloride
373-88-6

2,2,2-trifluroethylamine hydrochloride

2-phenyl-1-[5-(trifluoromethyl)-1H-pyrazol-3-yl]ethanone

2-phenyl-1-[5-(trifluoromethyl)-1H-pyrazol-3-yl]ethanone

Conditions
ConditionsYield
With sodium nitrite In dichloromethane; water at 0 - 20℃; for 24h;99%
ethynyl(diphenyl)phosphine oxide
6104-48-9

ethynyl(diphenyl)phosphine oxide

2,2,2-trifluroethylamine hydrochloride
373-88-6

2,2,2-trifluroethylamine hydrochloride

3-(diphenylphosphoryl)-5-(trifluoromethyl)-1H-pyrazole

3-(diphenylphosphoryl)-5-(trifluoromethyl)-1H-pyrazole

Conditions
ConditionsYield
With sodium nitrite In dichloromethane; water at 0 - 20℃; for 24h;99%
2,2,2-trifluroethylamine hydrochloride
373-88-6

2,2,2-trifluroethylamine hydrochloride

methyl ethenyl sulphone
3680-02-2

methyl ethenyl sulphone

3-(methylsulfonyl)-5-(trifluoromethyl)-4,5-dihydro-1H-pyrazole

3-(methylsulfonyl)-5-(trifluoromethyl)-4,5-dihydro-1H-pyrazole

Conditions
ConditionsYield
Stage #1: 2,2,2-trifluroethylamine hydrochloride; methyl ethenyl sulphone With sodium nitrite In dichloromethane; water at 20℃; for 14h;
Stage #2: With silica gel In ethyl acetate; toluene
99%
ethyl vinyl sulfone
1889-59-4

ethyl vinyl sulfone

2,2,2-trifluroethylamine hydrochloride
373-88-6

2,2,2-trifluroethylamine hydrochloride

3-(ethylsulfonyl)-5-(trifluoromethyl)-4,5-dihydro-1H-pyrazole

3-(ethylsulfonyl)-5-(trifluoromethyl)-4,5-dihydro-1H-pyrazole

Conditions
ConditionsYield
Stage #1: ethyl vinyl sulfone; 2,2,2-trifluroethylamine hydrochloride With sodium nitrite In dichloromethane; water at 20℃; for 14h;
Stage #2: With silica gel In ethyl acetate; toluene
99%
1-(vinylsulfonyl)-3-methylbenzene
5535-53-5

1-(vinylsulfonyl)-3-methylbenzene

2,2,2-trifluroethylamine hydrochloride
373-88-6

2,2,2-trifluroethylamine hydrochloride

3-((3-methylphenyl)sulfonyl)-5-(trifluoromethyl)-4,5-dihydro-1H-pyrazole

3-((3-methylphenyl)sulfonyl)-5-(trifluoromethyl)-4,5-dihydro-1H-pyrazole

Conditions
ConditionsYield
Stage #1: 1-(vinylsulfonyl)-3-methylbenzene; 2,2,2-trifluroethylamine hydrochloride With sodium nitrite In dichloromethane; water at 20℃; for 14h;
Stage #2: With silica gel In ethyl acetate; toluene
99%
methyl 2-(2-bromophenyl)-3-hydroxybut-2-enoate
1243144-97-9

methyl 2-(2-bromophenyl)-3-hydroxybut-2-enoate

2,2,2-trifluroethylamine hydrochloride
373-88-6

2,2,2-trifluroethylamine hydrochloride

(Z)-methyl 2-(2-bromophenyl)-3-((2,2,2-trifluoroethyl)amino)but-2-enoate

(Z)-methyl 2-(2-bromophenyl)-3-((2,2,2-trifluoroethyl)amino)but-2-enoate

Conditions
ConditionsYield
With lithium methanolate; acetic acid In methanol; ethanol at 85℃; for 18h; Inert atmosphere;98.4%
L-N-Boc-Ala
15761-38-3

L-N-Boc-Ala

2,2,2-trifluroethylamine hydrochloride
373-88-6

2,2,2-trifluroethylamine hydrochloride

tert-butyl (S)-1-(2,2,2-trifluoroethylcarbamoyl)ethylcarbamate
934178-98-0

tert-butyl (S)-1-(2,2,2-trifluoroethylcarbamoyl)ethylcarbamate

Conditions
ConditionsYield
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine In dichloromethane for 16h;98%
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 20℃; for 16h;98%
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine In dichloromethane
2,2,2-trifluroethylamine hydrochloride
373-88-6

2,2,2-trifluroethylamine hydrochloride

N2-(tert-butoxycarbonyl)-N-(2,2,2-trifluoroethyl)-D-alaninamide
934179-15-4

N2-(tert-butoxycarbonyl)-N-(2,2,2-trifluoroethyl)-D-alaninamide

Conditions
ConditionsYield
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine In dichloromethane for 16h;98%
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine In dichloromethane for 16h;
With N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate In N,N-dimethyl-formamide at 20℃; for 16h;
Boc-D-Val-OH
22838-58-0

Boc-D-Val-OH

2,2,2-trifluroethylamine hydrochloride
373-88-6

2,2,2-trifluroethylamine hydrochloride

(R)-tert-butyl 3-methyl-1-oxo-1-(2,2,2-trifluoroethylamino)butan-2-ylcarbamate
1429906-02-4

(R)-tert-butyl 3-methyl-1-oxo-1-(2,2,2-trifluoroethylamino)butan-2-ylcarbamate

Conditions
ConditionsYield
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In N,N-dimethyl-formamide at 20℃; for 16h;98%
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine In dichloromethane at 20℃;12.81 g
ethyl 2-(3-nitropyridin-2-yl)acrylate
1461708-12-2

ethyl 2-(3-nitropyridin-2-yl)acrylate

2,2,2-trifluroethylamine hydrochloride
373-88-6

2,2,2-trifluroethylamine hydrochloride

ethyl 3-(3-nitropyridin-2-yl)-5-(trifluoromethyl)-4,5-dihydro-3Hpyrazole-3-carboxylate

ethyl 3-(3-nitropyridin-2-yl)-5-(trifluoromethyl)-4,5-dihydro-3Hpyrazole-3-carboxylate

Conditions
ConditionsYield
With sodium nitrite In dichloromethane; water at 0 - 20℃; for 24h;98%
carbon monoxide
201230-82-2

carbon monoxide

2,2,2-trifluroethylamine hydrochloride
373-88-6

2,2,2-trifluroethylamine hydrochloride

trimethyl orthoformate
149-73-5

trimethyl orthoformate

3-amino-4-iodobenzonitrile

3-amino-4-iodobenzonitrile

C11H6F3N3O

C11H6F3N3O

Conditions
ConditionsYield
With palladium 10% on activated carbon; N-ethyl-N,N-diisopropylamine In toluene at 110℃; under 7500.75 Torr; for 20h; Autoclave;98%
tolyl vinyl sulfone
5535-52-4

tolyl vinyl sulfone

2,2,2-trifluroethylamine hydrochloride
373-88-6

2,2,2-trifluroethylamine hydrochloride

3-((4-methylphenyl)sulfonyl)-5-(trifluoromethyl)-4,5-dihydro-1H-pyrazole

3-((4-methylphenyl)sulfonyl)-5-(trifluoromethyl)-4,5-dihydro-1H-pyrazole

Conditions
ConditionsYield
Stage #1: tolyl vinyl sulfone; 2,2,2-trifluroethylamine hydrochloride With sodium nitrite In dichloromethane; water at 20℃; for 14h;
Stage #2: With silica gel In ethyl acetate; toluene
98%
2,2,2-trifluroethylamine hydrochloride
373-88-6

2,2,2-trifluroethylamine hydrochloride

p-tert-butyl benzoyl chloride
1710-98-1

p-tert-butyl benzoyl chloride

4-tert-butyl-N-(2,2,2-trifluoroethyl)benzamide
1228117-67-6

4-tert-butyl-N-(2,2,2-trifluoroethyl)benzamide

Conditions
ConditionsYield
With triethylamine In dichloromethane at 20℃; for 4h; Inert atmosphere;97%
2,2,2-trifluroethylamine hydrochloride
373-88-6

2,2,2-trifluroethylamine hydrochloride

dimethyl cis-but-2-ene-1,4-dioate
624-48-6

dimethyl cis-but-2-ene-1,4-dioate

dimethyl 5-(trifluoromethyl)-4,5-dihydro-1H-pyrazole-3,4-dicarboxylate

dimethyl 5-(trifluoromethyl)-4,5-dihydro-1H-pyrazole-3,4-dicarboxylate

Conditions
ConditionsYield
With sodium nitrite In dichloromethane; water at 0 - 20℃; for 24h;97%
2,2,2-trifluroethylamine hydrochloride
373-88-6

2,2,2-trifluroethylamine hydrochloride

acrylonitrile
107-13-1

acrylonitrile

5-(trifluoromethyl)-4,5-dihydro-1H-pyrazole-3-carbonitrile
69918-43-0

5-(trifluoromethyl)-4,5-dihydro-1H-pyrazole-3-carbonitrile

Conditions
ConditionsYield
With sodium nitrite In dichloromethane; water at 0 - 20℃; for 24h;97%
carbon monoxide
201230-82-2

carbon monoxide

4-fluoro-2-iodoaniline
61272-76-2

4-fluoro-2-iodoaniline

2,2,2-trifluroethylamine hydrochloride
373-88-6

2,2,2-trifluroethylamine hydrochloride

trimethyl orthoformate
149-73-5

trimethyl orthoformate

C10H6F4N2O

C10H6F4N2O

Conditions
ConditionsYield
With palladium 10% on activated carbon; N-ethyl-N,N-diisopropylamine In toluene at 110℃; under 7500.75 Torr; for 20h; Autoclave;97%
4-bromonitrosobenzene
3623-23-2

4-bromonitrosobenzene

2,2,2-trifluroethylamine hydrochloride
373-88-6

2,2,2-trifluroethylamine hydrochloride

dimethyl cis-but-2-ene-1,4-dioate
624-48-6

dimethyl cis-but-2-ene-1,4-dioate

dimethyl 2-(4-bromophenyl)-3-(trifluoromethyl)isoxazolidine-4,5-dicarboxylate

dimethyl 2-(4-bromophenyl)-3-(trifluoromethyl)isoxazolidine-4,5-dicarboxylate

Conditions
ConditionsYield
Stage #1: 2,2,2-trifluroethylamine hydrochloride With sodium nitrite In water; 1,2-dichloro-ethane at 0℃; for 2h;
Stage #2: 4-bromonitrosobenzene; dimethyl cis-but-2-ene-1,4-dioate In water; 1,2-dichloro-ethane at -78 - 70℃; for 16h;
96%
2,2,2-trifluroethylamine hydrochloride
373-88-6

2,2,2-trifluroethylamine hydrochloride

dimethyl acetylenedicarboxylate
762-42-5

dimethyl acetylenedicarboxylate

dimethyl 3-(trifluoromethyl)-1H-pyrazole-4,5-di-carboxylate

dimethyl 3-(trifluoromethyl)-1H-pyrazole-4,5-di-carboxylate

Conditions
ConditionsYield
With sodium nitrite In dichloromethane; water at 0 - 20℃; for 24h;96%
N-phenyl-maleimide
941-69-5

N-phenyl-maleimide

2,2,2-trifluroethylamine hydrochloride
373-88-6

2,2,2-trifluroethylamine hydrochloride

5-phenyl-3-(trifluoromethyl)-3a,6a-dihydropyrrolo[3,4-c]pyrazole-4,6(3H,5H)-dione

5-phenyl-3-(trifluoromethyl)-3a,6a-dihydropyrrolo[3,4-c]pyrazole-4,6(3H,5H)-dione

Conditions
ConditionsYield
With sodium nitrite In dichloromethane; water at 0 - 20℃; for 24h;96%
carbon monoxide
201230-82-2

carbon monoxide

p-chloro-o-iodoaniline
63069-48-7

p-chloro-o-iodoaniline

2,2,2-trifluroethylamine hydrochloride
373-88-6

2,2,2-trifluroethylamine hydrochloride

trimethyl orthoformate
149-73-5

trimethyl orthoformate

C10H6ClF3N2O

C10H6ClF3N2O

Conditions
ConditionsYield
With palladium 10% on activated carbon; N-ethyl-N,N-diisopropylamine In toluene at 110℃; under 7500.75 Torr; for 20h; Autoclave;96%
carbon monoxide
201230-82-2

carbon monoxide

2-iodophenylamine
615-43-0

2-iodophenylamine

2,2,2-trifluroethylamine hydrochloride
373-88-6

2,2,2-trifluroethylamine hydrochloride

trimethyl orthoformate
149-73-5

trimethyl orthoformate

3-(2,2,2-trifluoroethyl)quinazolin-4(3H)-one

3-(2,2,2-trifluoroethyl)quinazolin-4(3H)-one

Conditions
ConditionsYield
With palladium 10% on activated carbon; N-ethyl-N,N-diisopropylamine In toluene at 110℃; under 7500.75 Torr; for 20h; Autoclave;96%
C17H15NO

C17H15NO

2,2,2-trifluroethylamine hydrochloride
373-88-6

2,2,2-trifluroethylamine hydrochloride

2-phenyl-3-(o-tolyl)-7-(trifluoromethyl)-2,5,6-triazaspiro[3.4]oct-6-en-1-one

2-phenyl-3-(o-tolyl)-7-(trifluoromethyl)-2,5,6-triazaspiro[3.4]oct-6-en-1-one

Conditions
ConditionsYield
Stage #1: 2,2,2-trifluroethylamine hydrochloride With sodium nitrite In water; acetonitrile at 0℃; for 1h; Schlenk technique;
Stage #2: C17H15NO In water; acetonitrile at 60℃; Schlenk technique; Sealed tube; stereoselective reaction;
96%
C11H14S

C11H14S

2,2,2-trifluroethylamine hydrochloride
373-88-6

2,2,2-trifluroethylamine hydrochloride

(4-ethylphenyl)(1,1,1-trifluoropent-4-en-2-yl)sulfane

(4-ethylphenyl)(1,1,1-trifluoropent-4-en-2-yl)sulfane

Conditions
ConditionsYield
With meso-tetraphenylporphyrin iron(III) chloride; sodium nitrite In dichloromethane; water at 20℃; for 15h; Inert atmosphere;96%

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