ascofuranone CAS:38462-04-3 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic intermediate
Cas:38462-04-3
Min.Order:1 Gram
Negotiable
Type:Lab/Research institutions
inquiryHello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai
Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod
Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi
Cas:38462-04-3
Min.Order:10 Gram
FOB Price: $100.0
Type:Lab/Research institutions
inquiryJ&H CHEM is one of China's leading providers of integrated fine chemical services including offering, research and development, Custom manufacturing business, as well as other Value-added customer services, for diversified range products of chemicals
1.Our services:A.Supply sampleB.The packing also can be according the customers` requirmentC.Any inquiries will be replied within 24 hoursD.we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate.
Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali
factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin
Good Quality Package:1kg/bag Application:Medical or chemical Transportation:Air/Train/Sea Port:Shenzhen
factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin
HuBei ipure is a diversified product production and operation enterprise, with API, pharma intermediates, and other fine chemicals as well as R&D and pigments development and sales as one of the large enterprises, with more than 130 acres of pl
Cas:38462-04-3
Min.Order:1 Gram
FOB Price: $1.0
Type:Trading Company
inquiryChengdu Push Bio-technology Co., Ltd. provides more than 4,000 natural monomeric substances, including approximately 6,000 products at different grades, specifications and purities. We have specialized in the R&D of medicinally active ingredients sta
High quality Short lead time Cost competitiveness Application:Antiviral
(1''S,4''S)-(-)-ascofuranol
Ascofuranone
Conditions | Yield |
---|---|
With pyridinium chlorochromate In dichloromethane for 3h; Ambient temperature; | 22.2% |
(2E,6E,1'S,4'S)-(+)-7-(4'-hydroxy-3',3'-dimethyl-2'-oxacyclopentyl)-3,7-dimethyl-2,6-heptadienyl acetate
Ascofuranone
Conditions | Yield |
---|---|
Multi-step reaction with 9 steps 1: imidazole / dimethylformamide / 6 h / Ambient temperature 2: 92.9 percent / K2CO3 / methanol; H2O / 48 h / Ambient temperature 3: 1.26 g / n-BuLi, Ph3CH, p-TsCl, LiCl / diethyl ether; hexamethylphosphoric acid triamide; hexane / 0.42 h / 0 °C 4: n-BuLi, HMPA / tetrahydrofuran; hexane / 0.75 h / -70 °C 5: 50.2 percent / CaCO3, NCS / H2O; dimethylformamide / Ambient temperature 6: 57 percent / DBU / tetrahydrofuran / 6 h / Heating 7: 1) EtMgBr / 1) ether, room temp., 1 h. 10 min.; 2) ether evaporated; 100 degC, 10 min. 8: 71 percent / HF / acetonitrile; H2O / 1 h / Ambient temperature 9: 22.2 percent / pyridinium chlorochromate / CH2Cl2 / 3 h / Ambient temperature View Scheme |
(2E,6E,1'S*,4'S*)-7-(4'-hydroxy-3',3'-dimethyl-2'-oxacyclopentyl)-3,7-dimethyl-2,6-heptadienyl acetate
Ascofuranone
Conditions | Yield |
---|---|
Multi-step reaction with 11 steps 1: 5.14 g / 14 h / 80 °C 2: 76.3 percent / Et3N, HSiCl3 / benzene / 96 h / Ambient temperature 3: imidazole / dimethylformamide / 6 h / Ambient temperature 4: 92.9 percent / K2CO3 / methanol; H2O / 48 h / Ambient temperature 5: 1.26 g / n-BuLi, Ph3CH, p-TsCl, LiCl / diethyl ether; hexamethylphosphoric acid triamide; hexane / 0.42 h / 0 °C 6: n-BuLi, HMPA / tetrahydrofuran; hexane / 0.75 h / -70 °C 7: 50.2 percent / CaCO3, NCS / H2O; dimethylformamide / Ambient temperature 8: 57 percent / DBU / tetrahydrofuran / 6 h / Heating 9: 1) EtMgBr / 1) ether, room temp., 1 h. 10 min.; 2) ether evaporated; 100 degC, 10 min. 10: 71 percent / HF / acetonitrile; H2O / 1 h / Ambient temperature 11: 22.2 percent / pyridinium chlorochromate / CH2Cl2 / 3 h / Ambient temperature View Scheme |
(2E,6E,1'S,4'S)-(+)-7-(4'-t-butyldimethylsilyloxy-3',3'-dimethyl-2'-oxacyclopentyl)-3,7-dimethyl-2,6-heptadien-1-ol
Ascofuranone
Conditions | Yield |
---|---|
Multi-step reaction with 7 steps 1: 1.26 g / n-BuLi, Ph3CH, p-TsCl, LiCl / diethyl ether; hexamethylphosphoric acid triamide; hexane / 0.42 h / 0 °C 2: n-BuLi, HMPA / tetrahydrofuran; hexane / 0.75 h / -70 °C 3: 50.2 percent / CaCO3, NCS / H2O; dimethylformamide / Ambient temperature 4: 57 percent / DBU / tetrahydrofuran / 6 h / Heating 5: 1) EtMgBr / 1) ether, room temp., 1 h. 10 min.; 2) ether evaporated; 100 degC, 10 min. 6: 71 percent / HF / acetonitrile; H2O / 1 h / Ambient temperature 7: 22.2 percent / pyridinium chlorochromate / CH2Cl2 / 3 h / Ambient temperature View Scheme |
(2E,6E,1'S,4'S)-7-(4'-t-butyldimethylsilyloxy-3',3'-dimethyl-2'-oxacyclopentyl)-3,7-dimethyl-2,6-heptadienyl chloride
Ascofuranone
Conditions | Yield |
---|---|
Multi-step reaction with 6 steps 1: n-BuLi, HMPA / tetrahydrofuran; hexane / 0.75 h / -70 °C 2: 50.2 percent / CaCO3, NCS / H2O; dimethylformamide / Ambient temperature 3: 57 percent / DBU / tetrahydrofuran / 6 h / Heating 4: 1) EtMgBr / 1) ether, room temp., 1 h. 10 min.; 2) ether evaporated; 100 degC, 10 min. 5: 71 percent / HF / acetonitrile; H2O / 1 h / Ambient temperature 6: 22.2 percent / pyridinium chlorochromate / CH2Cl2 / 3 h / Ambient temperature View Scheme |
(2E,6E,1'S,4'S)-(+)-7-(4'-t-butyldimethylsilyloxy-3',3'-dimethyl-2'-oxacyclopentyl)-3,7-dimethyl-2,6-heptadienyl acetate
Ascofuranone
Conditions | Yield |
---|---|
Multi-step reaction with 8 steps 1: 92.9 percent / K2CO3 / methanol; H2O / 48 h / Ambient temperature 2: 1.26 g / n-BuLi, Ph3CH, p-TsCl, LiCl / diethyl ether; hexamethylphosphoric acid triamide; hexane / 0.42 h / 0 °C 3: n-BuLi, HMPA / tetrahydrofuran; hexane / 0.75 h / -70 °C 4: 50.2 percent / CaCO3, NCS / H2O; dimethylformamide / Ambient temperature 5: 57 percent / DBU / tetrahydrofuran / 6 h / Heating 6: 1) EtMgBr / 1) ether, room temp., 1 h. 10 min.; 2) ether evaporated; 100 degC, 10 min. 7: 71 percent / HF / acetonitrile; H2O / 1 h / Ambient temperature 8: 22.2 percent / pyridinium chlorochromate / CH2Cl2 / 3 h / Ambient temperature View Scheme |
(2'E,6'E,1''S,4''S)-(+)-3-<7'-(4''-t-butyldimethylsilyloxy-3'',3''-dimethyl-2''-oxacyclopentyl)-3',7'-dimethyl-2',6'-heptadienyl>-2,4-dimethoxy-6-methyl-1,4-cyclohexadiene
Ascofuranone
Conditions | Yield |
---|---|
Multi-step reaction with 5 steps 1: 50.2 percent / CaCO3, NCS / H2O; dimethylformamide / Ambient temperature 2: 57 percent / DBU / tetrahydrofuran / 6 h / Heating 3: 1) EtMgBr / 1) ether, room temp., 1 h. 10 min.; 2) ether evaporated; 100 degC, 10 min. 4: 71 percent / HF / acetonitrile; H2O / 1 h / Ambient temperature 5: 22.2 percent / pyridinium chlorochromate / CH2Cl2 / 3 h / Ambient temperature View Scheme |
(2'E,6'E,1''S,4''S)-4-chloro-2-<7'-(4''-t-butyldimethylsilyloxy-3'',3''-dimethyl-2''-oxacyclopentyl)-3',7'-dimethyl-2',6'-heptadienyl>orcinol
Ascofuranone
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: 1) EtMgBr / 1) ether, room temp., 1 h. 10 min.; 2) ether evaporated; 100 degC, 10 min. 2: 71 percent / HF / acetonitrile; H2O / 1 h / Ambient temperature 3: 22.2 percent / pyridinium chlorochromate / CH2Cl2 / 3 h / Ambient temperature View Scheme |
(2'E,6'E,1''S,4''S)-3-<7'-(4''-t-butyldimethylsilyloxy-3'',3''-dimethyl-2''-oxacyclopentyl)-3',7'-dimethyl-2',6'-heptadienyl>-1,5-dichloro-6-methyl-2,4-cyclohexanedione
Ascofuranone
Conditions | Yield |
---|---|
Multi-step reaction with 4 steps 1: 57 percent / DBU / tetrahydrofuran / 6 h / Heating 2: 1) EtMgBr / 1) ether, room temp., 1 h. 10 min.; 2) ether evaporated; 100 degC, 10 min. 3: 71 percent / HF / acetonitrile; H2O / 1 h / Ambient temperature 4: 22.2 percent / pyridinium chlorochromate / CH2Cl2 / 3 h / Ambient temperature View Scheme |
(2'E,6'E,1''S,4''S)-5-chloro-2,4-dihydroxy-6-methyl-3-<7'-(4''-t-butyldimethylsilyloxy-3'',3''-dimethyl-2''-oxacyclopentyl)-3',7'-dimethyl-2',6'-heptadienyl>benzaldehyde
Ascofuranone
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: 71 percent / HF / acetonitrile; H2O / 1 h / Ambient temperature 2: 22.2 percent / pyridinium chlorochromate / CH2Cl2 / 3 h / Ambient temperature View Scheme |
Acetic acid (2E,6E)-7-[(2S,4S)-5,5-dimethyl-4-((R)-1-naphthalen-1-yl-ethylcarbamoyloxy)-tetrahydro-furan-2-yl]-3-methyl-octa-2,6-dienyl ester
Ascofuranone
Conditions | Yield |
---|---|
Multi-step reaction with 10 steps 1: 76.3 percent / Et3N, HSiCl3 / benzene / 96 h / Ambient temperature 2: imidazole / dimethylformamide / 6 h / Ambient temperature 3: 92.9 percent / K2CO3 / methanol; H2O / 48 h / Ambient temperature 4: 1.26 g / n-BuLi, Ph3CH, p-TsCl, LiCl / diethyl ether; hexamethylphosphoric acid triamide; hexane / 0.42 h / 0 °C 5: n-BuLi, HMPA / tetrahydrofuran; hexane / 0.75 h / -70 °C 6: 50.2 percent / CaCO3, NCS / H2O; dimethylformamide / Ambient temperature 7: 57 percent / DBU / tetrahydrofuran / 6 h / Heating 8: 1) EtMgBr / 1) ether, room temp., 1 h. 10 min.; 2) ether evaporated; 100 degC, 10 min. 9: 71 percent / HF / acetonitrile; H2O / 1 h / Ambient temperature 10: 22.2 percent / pyridinium chlorochromate / CH2Cl2 / 3 h / Ambient temperature View Scheme |
Conditions | Yield |
---|---|
With pyridine at 20℃; Product distribution / selectivity; | 100% |
Conditions | Yield |
---|---|
With potassium carbonate In acetone for 1h; Heating / reflux; | 93% |
ethyl bromoacetate
Ascofuranone
Conditions | Yield |
---|---|
Stage #1: Ascofuranone With sodium hydride In N,N-dimethyl-formamide at 20℃; for 0.166667h; Stage #2: ethyl bromoacetate In N,N-dimethyl-formamide at 40℃; for 5.5h; | 88% |
Conditions | Yield |
---|---|
With potassium carbonate In acetone for 1h; Heating; | 87% |
Conditions | Yield |
---|---|
With pyridine at 20℃; | 68% |
pyridine-3-carbonyl chloride hydrochloride
Ascofuranone
Conditions | Yield |
---|---|
With pyridine at 20℃; | 67% |
isonicotinoyl chloride hydrochloride
Ascofuranone
Conditions | Yield |
---|---|
In pyridine at 20℃; for 1h; | 54% |
Stage #1: isonicotinoyl chloride hydrochloride; Ascofuranone With pyridine at 20℃; for 1h; Stage #2: With water at 20℃; for 0.5h; | 54% |
Conditions | Yield |
---|---|
With pyridine; dmap at 50℃; | 32% |
Ascofuranone
3-chloro-4,6-dihydroxy-2-methyl-5-[3-methyl-7-(tetrahydro-5,5-dimethyl-4-oxo-2-furanyl)octyl]-benzaldehyde
Conditions | Yield |
---|---|
With hydrogen; 5%-palladium/activated carbon In ethanol at 0℃; for 3h; | 25% |
Ascofuranone
Conditions | Yield |
---|---|
With sodium hydroxide; silver nitrate In 1,4-dioxane at 20℃; for 3h; | 24% |
With sodium hydroxide; silver nitrate In 1,4-dioxane; water at 20℃; for 3h; | 24% |
Ascofuranone
Conditions | Yield |
---|---|
With pyridine; hydroxylamine hydrochloride at 20 - 25℃; for 3.5h; | 20% |
Ascofuranone
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: 68 percent / pyridine / 20 °C 2: 24 percent / K2CO3 / acetone / 2 h / Heating 3: 90 percent / aq. NaOH / methanol / 4 h / 20 °C View Scheme |
Ascofuranone
4-O-Acetyl-2-O-methyl-ascofuranone
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: 68 percent / pyridine / 20 °C 2: 24 percent / K2CO3 / acetone / 2 h / Heating View Scheme |
Ascofuranone
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1.1: NaH / dimethylformamide / 0.17 h / 20 °C 1.2: 88 percent / dimethylformamide / 5.5 h / 40 °C 2.1: 91 percent / aq. K2CO3 / methanol / 2 h / 20 °C View Scheme |
About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia
Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog
©2008 LookChem.com,License: ICP
NO.:Zhejiang16009103
complaints:service@lookchem.com Desktop View