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Dayang Chem (Hangzhou) Co.,Ltd.

DayangChem exported this product to many countries and regions at best price. If you are looking for the material's manufacturer or supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product spe

2-Aminoethylmethyl sulfone

Cas:49773-20-8

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Shanghai Upbio Tech Co.,Ltd

1.In No Less 10 years exporting experience. you can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specializ

Ethanamine,2-(methylsulfonyl)-

Cas:49773-20-8

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Ethanamine,2-(methylsulfonyl)-

Cas:49773-20-8

Min.Order:1 Kilogram

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Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

CAS NO.:49773-20-8

Cas:49773-20-8

Min.Order:0

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Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

Ethanamine,2-(methylsulfonyl)-

Cas:49773-20-8

Min.Order:0

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Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 6 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O

49773-20-8 2-Aminoethylmethyl sulfone

Cas:49773-20-8

Min.Order:1 Kilogram

FOB Price: $1000.0

Type:Lab/Research institutions

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Zibo Dorne chemical technology co. LTD

Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,

2-Aminoethylmethyl sulfone

Cas:49773-20-8

Min.Order:1 Metric Ton

Negotiable

Type:Lab/Research institutions

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Xiamen Jenny Chemical Technology Co., Ltd.

GMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,

2-Aminoethylmethylsulfone

Cas:49773-20-8

Min.Order:1 Milligram

Negotiable

Type:Trading Company

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KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

49773-20-8 CAS NO.49773-20-8

Cas:49773-20-8

Min.Order:1 Metric Ton

FOB Price: $7.0 / 8.0

Type:Trading Company

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GIHI CHEMICALS CO.,LIMITED

high purity,in stock Package:25kg/drum,or as per customers'demand Application:API,Pharmaceutical intermediates Transportation:air,sea,courier

2-Aminoethylmethyl sulfone

Cas:49773-20-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Henan Allgreen Chemical Co.,Ltd

high quality Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea

2-AMinoethylMethyl sulfone

Cas:49773-20-8

Min.Order:0

Negotiable

Type:Manufacturers

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Xian Changyue Biological Technology Co., Ltd.

best seller Application:API

2-Aminoethylmethyl sulfone

Cas:49773-20-8

Min.Order:0

Negotiable

Type:Manufacturers

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Antimex Chemical Limied

Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

Ethanamine,2-(methylsulfonyl)-

Cas:49773-20-8

Min.Order:0

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DB BIOTECH CO., LTD

best seller Application:API

2-Aminoethylmethyl sulfone

Cas:49773-20-8

Min.Order:0

Negotiable

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Changchun Artel lmport and Export trade company

Supply top quality products with a reasonable price Application:api

49773-20-8

Cas:49773-20-8

Min.Order:0

Negotiable

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Hangzhou Fandachem Co.,Ltd

2-Aminoethylmethyl sulfone cas 49773-20-8Appearance:white crystalline powder Storage:Store in dry, dark and ventilated place Package:25KG drum Application:intermediate Transportation:by air, by sea, by express

2-Aminoethylmethyl sulfone cas 49773-20-8

Cas:49773-20-8

Min.Order:0

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Type:Other

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Henan Kanbei Chemical Co.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

2-Aminoethylmethyl sulfone

Cas:49773-20-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Hebei Muhuang Technology Co., Ltd

best seller Application:API

2-Aminoethylmethyl sulfone

Cas:49773-20-8

Min.Order:0

Negotiable

Type:Trading Company

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Chemsigma International Co.,Ltd.

bulk?production Application:Pharmaceutical intermediates

2-Aminoethylmethyl sulfone

Cas:49773-20-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

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ZHEJIANG JIUZHOU CHEM CO.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

2-Aminoethylmethyl sulfone

Cas:49773-20-8

Min.Order:0

Negotiable

Type:Trading Company

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Jilin haofei import and export trade Co.,Ltd

Price, service, company and transport advantage: 1. Best service, place of origin China, high quality, and reasonable price. 2. It's customers' right to choose the package (EMS, DHL, FEDEX, UPS). 3. It's customers' right

2-Aminoethylmethyl sulfone CAS NO.49773-20-8

Cas:49773-20-8

Min.Order:0

Negotiable

Type:Trading Company

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Shanghai united Scientific Co.,Ltd.

United Scientific Company Located in Shanghai of China , is a competitive player in the global specialty and fine chemical market. Fenghua has both the expertise and flexibility to produce a wide range of chemicals. Focusing on developing the innovat

Ethanamine,2-(methylsulfonyl)-

Cas:49773-20-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Nanjing Raymon Biotech Co., Ltd.

Ethanamine,2-(methylsulfonyl)- Storage:keep in dry and cool condition Package:25kg or according to cutomer's demand Application:Chemical research/pharma intermediate Transportation:By Sea,by Air,By courier like DHL or Fedx. Port:Shanghai/Shenzhen

Ethanamine,2-(methylsulfonyl)-

Cas:49773-20-8

Min.Order:0

Negotiable

Type:Trading Company

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Shanghai Yongyi Biotechnology Co., Ltd

2-Aminoethylmethyl sulfone

Cas:49773-20-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Suzhou CarbonWell Pharma-Tech Co., Ltd

Package:1Kg~100Kg

2-Aminoethylmethyl sulfone

Cas:49773-20-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Beyond Pharmaceutical Co., Ltd

Used in medicine Application:Used in medicine

2-(methylsulfonyl)ethanamine HCl

Cas:49773-20-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Chemical Co.Ltd

Manufacturer,strong R&D,professional team Storage:Store in a cool, dry place. Store in a tightly closed container. Package:according to your requirement Application:ZhiShang Chemical is owned by ZhiShang Group, is a professional new-type chemicals en

Ethanamine,2-(methylsulfonyl)-

Cas:49773-20-8

Min.Order:0

Negotiable

Type:Trading Company

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Affinitis Pharma LLC

2-Aminoethylmethyl sulfone

Cas:49773-20-8

Min.Order:0

Negotiable

Type:Trading Company

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Synthetic route

methanesulfonyl-acetonitrile
2274-42-2

methanesulfonyl-acetonitrile

2-Methanesulfonyl-ethylamine
49773-20-8

2-Methanesulfonyl-ethylamine

Conditions
ConditionsYield
Stage #1: methanesulfonyl-acetonitrile With dimethylsulfide borane complex In tetrahydrofuran at 20 - 40℃; for 14h;
Stage #2: With methanol In tetrahydrofuran at 0 - 80℃; for 2h; Reflux;
90%
With dimethylsulfide borane complex In tetrahydrofuran
2-<2-(methylsulfonyl)ethyl>-1H-isoindole-1,3(2H)dione

2-<2-(methylsulfonyl)ethyl>-1H-isoindole-1,3(2H)dione

2-Methanesulfonyl-ethylamine
49773-20-8

2-Methanesulfonyl-ethylamine

Conditions
ConditionsYield
With hydrazine In ethanol; chloroform at 0 - 20℃;80%
BH3·THF

BH3·THF

methanesulfonyl-acetonitrile
2274-42-2

methanesulfonyl-acetonitrile

2-Methanesulfonyl-ethylamine
49773-20-8

2-Methanesulfonyl-ethylamine

Conditions
ConditionsYield
With hydrogenchloride; sodium methylate In tetrahydrofuran; methanol; dichloromethane77.89%
2-methylsulfonylethyl methanesulfonate
191604-52-1

2-methylsulfonylethyl methanesulfonate

2-Methanesulfonyl-ethylamine
49773-20-8

2-Methanesulfonyl-ethylamine

Conditions
ConditionsYield
With ammonia In dichloromethane at 45℃; under 1500.15 Torr; for 3h; Pressure; Temperature; Inert atmosphere;66.9%
2-chloroethyl methyl sulfone
50890-51-2

2-chloroethyl methyl sulfone

A

2-Methanesulfonyl-ethylamine
49773-20-8

2-Methanesulfonyl-ethylamine

B

bis-(2-methanesulfonyl-ethyl)-amine

bis-(2-methanesulfonyl-ethyl)-amine

Conditions
ConditionsYield
With ammonia
methyl-(2-nitro-ethyl)-sulfone

methyl-(2-nitro-ethyl)-sulfone

2-Methanesulfonyl-ethylamine
49773-20-8

2-Methanesulfonyl-ethylamine

Conditions
ConditionsYield
With methanol; nickel Hydrogenation;
(2-aminoethyl)methylsulfide
18542-42-2

(2-aminoethyl)methylsulfide

KMnO4

KMnO4

2-Methanesulfonyl-ethylamine
49773-20-8

2-Methanesulfonyl-ethylamine

2-chloroethyl methyl sulfone
50890-51-2

2-chloroethyl methyl sulfone

A

2-Methanesulfonyl-ethylamine
49773-20-8

2-Methanesulfonyl-ethylamine

B

β.β'-bis-methanesulfonyl-diethylamine

β.β'-bis-methanesulfonyl-diethylamine

Conditions
ConditionsYield
With ammonia
[2-(methylsulfonyl)ethyl]trifluoroacetamide
202197-68-0

[2-(methylsulfonyl)ethyl]trifluoroacetamide

2-Methanesulfonyl-ethylamine
49773-20-8

2-Methanesulfonyl-ethylamine

Conditions
ConditionsYield
Alkaline hydrolysis;
(2-methanesulfonyl-ethyl)-carbamic acid benzyl ester
146698-94-4

(2-methanesulfonyl-ethyl)-carbamic acid benzyl ester

2-Methanesulfonyl-ethylamine
49773-20-8

2-Methanesulfonyl-ethylamine

Conditions
ConditionsYield
With hydrogen; palladium on activated charcoal In ethanol
C10H15NO3S

C10H15NO3S

2-Methanesulfonyl-ethylamine
49773-20-8

2-Methanesulfonyl-ethylamine

Conditions
ConditionsYield
With ammonium formate; palladium 10% on activated carbon In methanol
2-(methylsulfonyl)ethyl 4-methylbenzenesulfonate
103275-86-1

2-(methylsulfonyl)ethyl 4-methylbenzenesulfonate

2-Methanesulfonyl-ethylamine
49773-20-8

2-Methanesulfonyl-ethylamine

Conditions
ConditionsYield
With ammonia In diethyl ether at 50℃; for 1h;
With ammonia
N,N-dibenzyl-2-(methylsulfonyl)ethylamine
824938-65-0

N,N-dibenzyl-2-(methylsulfonyl)ethylamine

2-Methanesulfonyl-ethylamine
49773-20-8

2-Methanesulfonyl-ethylamine

Conditions
ConditionsYield
With hydrogen; Raney nickel In ethanol
2-(methylsulfonyl)ethylamine hydrochloride
104458-24-4

2-(methylsulfonyl)ethylamine hydrochloride

2-Methanesulfonyl-ethylamine
49773-20-8

2-Methanesulfonyl-ethylamine

Conditions
ConditionsYield
With sodium hydroxide In ethanol at 20℃; for 0.5h; Product distribution / selectivity;
With sodium methylate In methanol at 20℃; for 0.25h;
2-Methanesulfonyl-ethylamine
49773-20-8

2-Methanesulfonyl-ethylamine

C32H37N5O15

C32H37N5O15

C30H38N2O16S

C30H38N2O16S

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In dichloromethane for 0.166667h;98%
2-Methanesulfonyl-ethylamine
49773-20-8

2-Methanesulfonyl-ethylamine

6-(thiazol-5-yl)-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-indole-4-carboxylic acid

6-(thiazol-5-yl)-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-indole-4-carboxylic acid

N-(2-(methylsulfonyl)ethyl)-6-(thiazol-5-yl)-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-indole-4-carboxamide

N-(2-(methylsulfonyl)ethyl)-6-(thiazol-5-yl)-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-indole-4-carboxamide

Conditions
ConditionsYield
Stage #1: 6-(thiazol-5-yl)-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-indole-4-carboxylic acid With N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate In N,N-dimethyl-formamide at 0℃; for 0.166667h; Inert atmosphere;
Stage #2: 2-Methanesulfonyl-ethylamine In N,N-dimethyl-formamide at 20℃; for 16h; Inert atmosphere;
98%
1-(5-(methoxycarbonyl)-4-{[2-(trifluoromethyl)benzyl]oxy}thien-2-yl)-1H-benzimidazole-5-carboxylic acid
660870-46-2

1-(5-(methoxycarbonyl)-4-{[2-(trifluoromethyl)benzyl]oxy}thien-2-yl)-1H-benzimidazole-5-carboxylic acid

2-Methanesulfonyl-ethylamine
49773-20-8

2-Methanesulfonyl-ethylamine

methyl 5-[5-({[2-(methylsulfonyl)ethyl]amino}carbonyl)-1H-benzimidazol-1-yl]-3-{[2-(trifluoromethyl)benzyl]oxy}thiophene-2-carboxylate

methyl 5-[5-({[2-(methylsulfonyl)ethyl]amino}carbonyl)-1H-benzimidazol-1-yl]-3-{[2-(trifluoromethyl)benzyl]oxy}thiophene-2-carboxylate

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine; HATU In DMF (N,N-dimethyl-formamide) for 12h;95%
2-Methanesulfonyl-ethylamine
49773-20-8

2-Methanesulfonyl-ethylamine

toluene-4-sulfonic acid
104-15-4

toluene-4-sulfonic acid

5-(4-(3-chloro-4-(3-fluorobenzyloxy)phenylamino)quinazolin-6-yl)furan-2-carbaldehyde
231278-84-5

5-(4-(3-chloro-4-(3-fluorobenzyloxy)phenylamino)quinazolin-6-yl)furan-2-carbaldehyde

lapatinib ditosylate
388082-78-8

lapatinib ditosylate

Conditions
ConditionsYield
Stage #1: 2-Methanesulfonyl-ethylamine; 5-(4-(3-chloro-4-(3-fluorobenzyloxy)phenylamino)quinazolin-6-yl)furan-2-carbaldehyde In methanol; dichloromethane at 20℃;
Stage #2: With hydrogen In methanol; dichloromethane Inert atmosphere;
Stage #3: toluene-4-sulfonic acid In methanol; dichloromethane
93%
2-Methanesulfonyl-ethylamine
49773-20-8

2-Methanesulfonyl-ethylamine

toluene-4-sulfonic acid
104-15-4

toluene-4-sulfonic acid

5-(4-(3-chloro-4-(3-fluorobenzyloxy)phenylamino)quinazolin-6-yl)furan-2-carbaldehyde
231278-84-5

5-(4-(3-chloro-4-(3-fluorobenzyloxy)phenylamino)quinazolin-6-yl)furan-2-carbaldehyde

({5-[4-({3-chloro-4-[(3-fluorophenyl)methoxy]phenyl}amino)quinazolin-6-yl]furan-2-yl}methyl) [2-(methylsulfonyl)ethyl]azanium 4-methylbenzenesulfonate

({5-[4-({3-chloro-4-[(3-fluorophenyl)methoxy]phenyl}amino)quinazolin-6-yl]furan-2-yl}methyl) [2-(methylsulfonyl)ethyl]azanium 4-methylbenzenesulfonate

Conditions
ConditionsYield
Stage #1: 2-Methanesulfonyl-ethylamine; 5-(4-(3-chloro-4-(3-fluorobenzyloxy)phenylamino)quinazolin-6-yl)furan-2-carbaldehyde In methanol; dichloromethane at 20℃;
Stage #2: With hydrogen In methanol; dichloromethane Inert atmosphere;
Stage #3: toluene-4-sulfonic acid In methanol; dichloromethane; toluene Product distribution / selectivity;
93%
6-(2,4-difluorophenoxy)-8-methyl-2-(methylsulfonyl)pyrido[2,3-d]pyrimidin-7(8H)-one
449808-50-8

6-(2,4-difluorophenoxy)-8-methyl-2-(methylsulfonyl)pyrido[2,3-d]pyrimidin-7(8H)-one

2-Methanesulfonyl-ethylamine
49773-20-8

2-Methanesulfonyl-ethylamine

2-(2'-methylsulfonylethylamino)-6-(2,4-difluorophenoxy)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one
1280218-18-9

2-(2'-methylsulfonylethylamino)-6-(2,4-difluorophenoxy)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one

Conditions
ConditionsYield
In 1-methyl-pyrrolidin-2-one at 65℃; for 0.5h;92%
2-Methanesulfonyl-ethylamine
49773-20-8

2-Methanesulfonyl-ethylamine

C23H24N4O14

C23H24N4O14

C24H30N2O16S

C24H30N2O16S

Conditions
ConditionsYield
for 0.0833333h;92%
[(4-{[3-chloro-4-(pyridin-2-ylmethoxy)phenyl]amino}quinazolin-5-yl)oxy]acetic acid sodium salt
871018-54-1

[(4-{[3-chloro-4-(pyridin-2-ylmethoxy)phenyl]amino}quinazolin-5-yl)oxy]acetic acid sodium salt

2-Methanesulfonyl-ethylamine
49773-20-8

2-Methanesulfonyl-ethylamine

2-{4-[3-chloro-4-(pyridin-2-ylmethoxy)-phenylamino]-quinazolin-5-yloxy}-N-(2-methanesulfonyl-ethyl)-acetamide

2-{4-[3-chloro-4-(pyridin-2-ylmethoxy)-phenylamino]-quinazolin-5-yloxy}-N-(2-methanesulfonyl-ethyl)-acetamide

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine; HATU In DMF (N,N-dimethyl-formamide) at 65℃; for 18h;89%
2-Methanesulfonyl-ethylamine
49773-20-8

2-Methanesulfonyl-ethylamine

5-(4-[3-chloro-4-(3-fluorobenzyloxy)-anilino]-6-quinazolinyl)-furan-2-carbaldehyde tosylate

5-(4-[3-chloro-4-(3-fluorobenzyloxy)-anilino]-6-quinazolinyl)-furan-2-carbaldehyde tosylate

toluene-4-sulfonic acid
104-15-4

toluene-4-sulfonic acid

lapatinib ditosylate
388082-78-8

lapatinib ditosylate

Conditions
ConditionsYield
Stage #1: 2-Methanesulfonyl-ethylamine; 5-(4-[3-chloro-4-(3-fluorobenzyloxy)-anilino]-6-quinazolinyl)-furan-2-carbaldehyde tosylate With N-ethyl-N,N-diisopropylamine In tetrahydrofuran; isopropyl alcohol for 1h; Industrial scale;
Stage #2: With sodium tris(acetoxy)borohydride; isopropyl alcohol In tetrahydrofuran at 20℃; for 1.66667h; Industrial scale;
Stage #3: toluene-4-sulfonic acid Industrial scale; Further stages;
88%
2-Methanesulfonyl-ethylamine
49773-20-8

2-Methanesulfonyl-ethylamine

(S)-phenyl-N-(4-((3-chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)carbamate

(S)-phenyl-N-(4-((3-chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)carbamate

(S)-1-(4-(3-chloro-4-fluorophenylamino)-7-(tetrahydrofuran-3-yloxy)quinazolin-6-yl)-3-(2-(methylsulfonyl)ethyl)urea

(S)-1-(4-(3-chloro-4-fluorophenylamino)-7-(tetrahydrofuran-3-yloxy)quinazolin-6-yl)-3-(2-(methylsulfonyl)ethyl)urea

Conditions
ConditionsYield
In tetrahydrofuran at 70℃; for 4h;86%
2-Methanesulfonyl-ethylamine
49773-20-8

2-Methanesulfonyl-ethylamine

2-(3,4,5-trimethoxyphenyl)-5-methyloxazole-4-carboxylic acid
1198279-82-1

2-(3,4,5-trimethoxyphenyl)-5-methyloxazole-4-carboxylic acid

2-(3,4,5-dimethoxyphenyl)-5-methyl-N-(2-(methylsulfonyl)ethyl)oxazole-4-carboxamide

2-(3,4,5-dimethoxyphenyl)-5-methyl-N-(2-(methylsulfonyl)ethyl)oxazole-4-carboxamide

Conditions
ConditionsYield
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine In N,N-dimethyl-formamide at 20℃;86%
2-Methanesulfonyl-ethylamine
49773-20-8

2-Methanesulfonyl-ethylamine

(3aR,4R,5R,7S,8S,9R,9aS,12R)-8-hydroxy-4,7,9,12-tetramethyl-3-oxo-7-vinyldecahydro-4,9a-propanocyclopenta[8]annulen-5-yl 2-iodoacetate
31716-03-7

(3aR,4R,5R,7S,8S,9R,9aS,12R)-8-hydroxy-4,7,9,12-tetramethyl-3-oxo-7-vinyldecahydro-4,9a-propanocyclopenta[8]annulen-5-yl 2-iodoacetate

14-O-(hexadecyl)aminoacetylmutilin

14-O-(hexadecyl)aminoacetylmutilin

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 75℃; for 4h;85.31%
2-Methanesulfonyl-ethylamine
49773-20-8

2-Methanesulfonyl-ethylamine

5-(4-(3-chloro-4-(3-fluorobenzyloxy)phenylamino)quinazolin-6-yl)furan-2-carbaldehyde
231278-84-5

5-(4-(3-chloro-4-(3-fluorobenzyloxy)phenylamino)quinazolin-6-yl)furan-2-carbaldehyde

lapatanib
231277-92-2

lapatanib

Conditions
ConditionsYield
Stage #1: 2-Methanesulfonyl-ethylamine; 5-(4-(3-chloro-4-(3-fluorobenzyloxy)phenylamino)quinazolin-6-yl)furan-2-carbaldehyde In methanol; dichloromethane at 20℃;
Stage #2: With hydrogen In methanol; dichloromethane Inert atmosphere;
85%
Stage #1: 2-Methanesulfonyl-ethylamine; 5-(4-(3-chloro-4-(3-fluorobenzyloxy)phenylamino)quinazolin-6-yl)furan-2-carbaldehyde With sodium tris(acetoxy)borohydride; N-ethyl-N,N-diisopropylamine
Stage #2: With toluene-4-sulfonic acid
80%
Stage #1: 2-Methanesulfonyl-ethylamine; 5-(4-(3-chloro-4-(3-fluorobenzyloxy)phenylamino)quinazolin-6-yl)furan-2-carbaldehyde With triethylamine In tetrahydrofuran; methanol for 3h;
Stage #2: With methanol; sodium tetrahydroborate In tetrahydrofuran at 20℃; Cooling with ice;
70%
2-Methanesulfonyl-ethylamine
49773-20-8

2-Methanesulfonyl-ethylamine

2-(3,4-dimethoxyphenyl)-5-methyloxazole-4-carboxylic acid

2-(3,4-dimethoxyphenyl)-5-methyloxazole-4-carboxylic acid

2-(3,4-dimethoxyphenyl)-5-methyl-N-(2-(methylsulfonyl)ethyl)oxazole-4-carboxamide

2-(3,4-dimethoxyphenyl)-5-methyl-N-(2-(methylsulfonyl)ethyl)oxazole-4-carboxamide

Conditions
ConditionsYield
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine In N,N-dimethyl-formamide at 20℃;84%
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