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Dayang Chem (Hangzhou) Co.,Ltd.

DayangChem exported this product to many countries and regions at best price. If you are looking for the material's manufacturer or supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product spe

2-[Di(methylthio)methylidene]malononitrile Manufacturer/High quality/Best price/In stock

Cas:5147-80-8

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality [Bis(Methylthio)Methylene]Malononitrile supplier in China

Cas:5147-80-8

Min.Order:0 Metric Ton

Negotiable

Type:Manufacturers

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Henan Allgreen Chemical Co.,Ltd

high quality Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea Port:shanghai

2-[DI(METHYLTHIO)METHYLIDENE]MALONONITRILE

Cas:5147-80-8

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

2-[Di-(methylthio)-methylidene]-malononitrile

Cas:5147-80-8

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

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Henan Tianfu Chemical Co., Ltd.

Product Name: 2-[DI(METHYLTHIO)METHYLIDENE]MALONONITRILE Synonyms: 2-(Bis-methylsulfanyl-methylene)-malononitrile;[BIS(METHYLTHIO)METHYLENE]MALONONITRILE;[BIS(METHYLTHIO)METHYLENE]PROPANEDINITRILE;AKOS UB-20051;2-[DI(METHYLTHIO)METHYLIDENE]MALONON

2-[DI(METHYLTHIO)METHYLIDENE]MALONONITRILE 5147-80-8

Cas:5147-80-8

Min.Order:1 Kilogram

FOB Price: $230.0

Type:Lab/Research institutions

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Hebei Nengqian Chemical Import and Export Co., LTD

With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin

2-(bis(methylthio)methylene)malononitrile

Cas:5147-80-8

Min.Order:1 Kilogram

FOB Price: $100.0 / 150.0

Type:Trading Company

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Manufacturer supply CAS 5147-80-8 with best quality

Cas:5147-80-8

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

Propanedinitrile,2-[bis(methylthio)methylene]- 5147-80-8

Cas:5147-80-8

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Qingdao Beluga Import and Export Co., LTD

2-[DI(METHYLTHIO)METHYLIDENE]MALONONITRILE CAS:5147-80-8 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in hig

2-[DI(METHYLTHIO)METHYLIDENE]MALONONITRILE CAS:5147-80-8

Cas:5147-80-8

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Propanedinitrile,2-[bis(methylthio)methylene]-

Cas:5147-80-8

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

CAS NO.:5147-80-8

Cas:5147-80-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

[Bis(Methylthio)Methylene]Malononitrile

Cas:5147-80-8

Min.Order:0

Negotiable

Type:Manufacturers

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SHANGHAI T&W PHARMACEUTICAL CO., LTD.

A substitute for perfluorooctanoic acid, mainly used as a surfactant, dispersant, additive, etc Appearance:White solid or Colorless liquid Purity:99.3 % We will ship the goods in a timely manner as required We can provide relevant documents acc

[Bis(Methylthio)Methylene]Malononitrile

Cas:5147-80-8

Min.Order:4 Kilogram

Negotiable

Type:Lab/Research institutions

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Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

Propanedinitrile,2-[bis(methylthio)methylene]-

Cas:5147-80-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

High quality [Bis(Methylthio)Methylene]Malononitrile

Cas:5147-80-8

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

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Zibo Dorne chemical technology co. LTD

Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,

2-[DI(METHYLTHIO)METHYLIDENE]MALONONITRILE

Cas:5147-80-8

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Shanghai Minstar Chemical Co., Ltd

2-[DI(METHYLTHIO)METHYLIDENE]MALONONITRILE Basic information Product Name: 2-[DI(METHYLTHIO)METHYLIDENE]MALONONITRILE Synonyms: [BIS(METHYLTHIO)METHYLENE]MALONONITRILE;[BIS(METHYLTHIO)METHYLENE]PROPANEDINITRILE;AKOS UB-20051;2-[DI(METHYLTHIO)ME

2-[DI(METHYLTHIO)METHYLIDENE]MALONONITRILE

Cas:5147-80-8

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Win-Win chemical Co.Ltd

Stock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

2-[Di(methylthio)methylidene]malononitrile cas no. 5147-80-8 98%

Cas:5147-80-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Suzhou Sibian Chemical Technology Co., Ltd

The process is mature and can be mass produced to 100 kg, with good quality and purity up to 99%.The product has a large stock and can be supplied stably. Package:bottle Application:Drug R&D Transportation:Sealed drying(25℃) Port:ShangHai

2-[DI(METHYLTHIO)METHYLIDENE]MALONONITRILE

Cas:5147-80-8

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Lonwin Chemical Group Limited

Shanghai Lonwin Chemical company is a subsidiary of Lonwin Industry Group Limited, was established in 2011 and is headquartered in Shanghai, adjacent to China National Convention and Exhibition Center and Hongqiao transportation hub.Lonwinchem is

High Purity [Bis(Methylthio)Methylene]Malononitrile 5147-80-8

Cas:5147-80-8

Min.Order:100 Kilogram

FOB Price: $100.0 / 150.0

Type:Other

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GIHI CHEMICALS CO.,LIMITED

high purity,in stock Package:25kg/drum,or as per customers'demand Application:API,Pharmaceutical intermediates Transportation:air,sea,courier

2-[di-(Methylthio)methylidene]malononitrile

Cas:5147-80-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Aecochem Corp.

Our clients, like BASF,CHEMO,Brenntag,ASR,Evonik,Merck and etc.Appearance:COA Storage:in stock Application:MSDS/TDS

[Bis(Methylthio)Methylene]Malononitrile

Cas:5147-80-8

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Hubei Taiho Chemical Co.,LTD

TAIHO Unique Advantages:1.We're factory2.Free samples available3.Commodity inspection can be done4.ISO9001,Kosher certifications5.10 years experiences Storage:Store in cool &dry place Package:aluminium foil bag/fiber can/plastic drum Application:comp

Propanedinitrile, [bis(methylthio)methylene]-

Cas:5147-80-8

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Antimex Chemical Limied

Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

Propanedinitrile,2-[bis(methylthio)methylene]-

Cas:5147-80-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Xiamen AmoyChem Co.,Ltd

Amoychem is committed to providing the top-quality chemical products and services Internationally. We offer our customers with friendly, professional service and reliable, high performance products that have been manufactured according to the accredi

Bis(Methylthio)Methylene]Malo

Cas:5147-80-8

Min.Order:0

Negotiable

Type:Other

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BOC Sciences

We are committed to providing our customers with the best products and services at the most competitive prices.Appearance:light yellow liquid Storage:Room temperature with sealed well Package:according to the clients requirement Application:Use as pr

2-[Di(methylthio)methylidene]malononitrile

Cas:5147-80-8

Min.Order:0

Negotiable

Type:Trading Company

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Hangzhou Fandachem Co.,Ltd

2-[Di(methylthio)methylidene]malononitrile cas 5147-80-8Appearance:white crystalline powder Storage:Store in dry, dark and ventilated place Package:25KG drum Application:intermediate Transportation:by air, by sea, by express

2-[Di(methylthio)methylidene]malononitrile cas 5147-80-8

Cas:5147-80-8

Min.Order:0

Negotiable

Type:Other

inquiry

Hangzhou Sartort Biopharma Co., Ltd

Best quality with low priceAppearance:orange Storage:ln stock Package:25kg/Barrel Application:Chemicals Transportation:Express/Sea/Air Port:Shanghai

2-(bis(methylthio)methylene)malononitrile

Cas:5147-80-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Henan Kanbei Chemical Co.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

2-[DI(METHYLTHIO)METHYLIDENE]MALONONITRILE

Cas:5147-80-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Chemlyte Solutions

Stock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

2-[DI(METHYLTHIO)METHYLIDENE]MALONONITRILE

Cas:5147-80-8

Min.Order:0

Negotiable

Type:Other

inquiry

Synthetic route

carbon disulfide
75-15-0

carbon disulfide

malononitrile
109-77-3

malononitrile

methyl iodide
74-88-4

methyl iodide

[Bis(methylthio)methylene]malononitrile
5147-80-8

[Bis(methylthio)methylene]malononitrile

Conditions
ConditionsYield
With potassium carbonate; tetrabutylammomium bromide In benzene at 60℃; for 3h;100%
Stage #1: malononitrile With potassium carbonate In dimethyl sulfoxide at 20℃; for 0.166667h; Large scale reaction;
Stage #2: carbon disulfide In dimethyl sulfoxide at 0 - 22℃; for 0.5h; Large scale reaction;
Stage #3: methyl iodide In dimethyl sulfoxide at 5 - 20℃; Large scale reaction;
99%
Stage #1: carbon disulfide; malononitrile With potassium carbonate In dimethyl sulfoxide at 0 - 20℃; for 2h;
Stage #2: methyl iodide In dimethyl sulfoxide at 0 - 20℃; for 12h;
93.9%
potassium 1,1-dicyanoethylene-2,2-ditholate
4777-48-4

potassium 1,1-dicyanoethylene-2,2-ditholate

methyl iodide
74-88-4

methyl iodide

[Bis(methylthio)methylene]malononitrile
5147-80-8

[Bis(methylthio)methylene]malononitrile

Conditions
ConditionsYield
In water at 25 - 30℃; for 72h;89%
disodium iso-maleonitriledithiolate monohydrate
106719-99-7

disodium iso-maleonitriledithiolate monohydrate

methyl iodide
74-88-4

methyl iodide

[Bis(methylthio)methylene]malononitrile
5147-80-8

[Bis(methylthio)methylene]malononitrile

Conditions
ConditionsYield
86%
carbon disulfide
75-15-0

carbon disulfide

dimethyl sulfate
77-78-1

dimethyl sulfate

malononitrile
109-77-3

malononitrile

[Bis(methylthio)methylene]malononitrile
5147-80-8

[Bis(methylthio)methylene]malononitrile

Conditions
ConditionsYield
Stage #1: carbon disulfide; malononitrile With sodium ethanolate In ethanol at 20℃; for 1h;
Stage #2: dimethyl sulfate In ethanol
85%
Stage #1: malononitrile With potassium hydroxide In water; N,N-dimethyl-formamide at 0 - 20℃; for 2h;
Stage #2: carbon disulfide In water; N,N-dimethyl-formamide at 20℃; for 1.5h;
Stage #3: dimethyl sulfate In water; N,N-dimethyl-formamide at 0 - 20℃; for 4h;
85%
(i) NaOMe, MeOH, (ii) /BRN= 635994/; Multistep reaction;
Stage #1: malononitrile With potassium hydroxide at 20℃;
Stage #2: carbon disulfide
Stage #3: dimethyl sulfate
(S,S)-dimethyl trithiocarbonate
2314-48-9

(S,S)-dimethyl trithiocarbonate

C3Ag2N2

C3Ag2N2

[Bis(methylthio)methylene]malononitrile
5147-80-8

[Bis(methylthio)methylene]malononitrile

Conditions
ConditionsYield
In methanol
dimethyl sulfate
77-78-1

dimethyl sulfate

2-Dimercaptomethylene-malononitrile; compound with ammonia

2-Dimercaptomethylene-malononitrile; compound with ammonia

[Bis(methylthio)methylene]malononitrile
5147-80-8

[Bis(methylthio)methylene]malononitrile

Conditions
ConditionsYield
With sodium hydroxide
2,2-Dicyano-1-mercapto-ethenethiolatetetrabutyl-ammonium;
42717-51-1

2,2-Dicyano-1-mercapto-ethenethiolatetetrabutyl-ammonium;

methyl iodide
74-88-4

methyl iodide

[Bis(methylthio)methylene]malononitrile
5147-80-8

[Bis(methylthio)methylene]malononitrile

Conditions
ConditionsYield
In N,N-dimethyl-formamide
potassium (2,2-dicyano-1-methylsulfanylethen-1-yl)thiolate
20602-68-0

potassium (2,2-dicyano-1-methylsulfanylethen-1-yl)thiolate

methyl iodide
74-88-4

methyl iodide

[Bis(methylthio)methylene]malononitrile
5147-80-8

[Bis(methylthio)methylene]malononitrile

Conditions
ConditionsYield
In ethanol
dimercaptomethylene-malononitrile
18771-14-7

dimercaptomethylene-malononitrile

dimethyl sulfate
77-78-1

dimethyl sulfate

[Bis(methylthio)methylene]malononitrile
5147-80-8

[Bis(methylthio)methylene]malononitrile

Conditions
ConditionsYield
In dimethyl sulfoxide for 2h; Ambient temperature; Yield given;
2-(2,4-dithia-1,5-disodapentan-3-ylidene)propanedinitrile
4885-93-2

2-(2,4-dithia-1,5-disodapentan-3-ylidene)propanedinitrile

CH3X, X=halogen

CH3X, X=halogen

[Bis(methylthio)methylene]malononitrile
5147-80-8

[Bis(methylthio)methylene]malononitrile

Conditions
ConditionsYield
In isopropyl alcohol Heating;
carbon disulfide
75-15-0

carbon disulfide

malononitrile, sodium-compound

malononitrile, sodium-compound

[Bis(methylthio)methylene]malononitrile
5147-80-8

[Bis(methylthio)methylene]malononitrile

Conditions
ConditionsYield
With diethyl ether; methyl iodide Einwoechiges Erwaermen des Reaktionsgemisches mit Methyljodid.;
dimethyl sulfate
77-78-1

dimethyl sulfate

malononitrile
109-77-3

malononitrile

[Bis(methylthio)methylene]malononitrile
5147-80-8

[Bis(methylthio)methylene]malononitrile

Conditions
ConditionsYield
With carbon disulfide; sodium methylate In methanol18.6 g (11%)
carbon disulfide
75-15-0

carbon disulfide

malononitrile
109-77-3

malononitrile

[Bis(methylthio)methylene]malononitrile
5147-80-8

[Bis(methylthio)methylene]malononitrile

Conditions
ConditionsYield
alcoholic sodium methoxide
alcoholic sodium methoxide
2-(2,4-dithia-1,5-disodapentan-3-ylidene)propanedinitrile
4885-93-2

2-(2,4-dithia-1,5-disodapentan-3-ylidene)propanedinitrile

methyl iodide
74-88-4

methyl iodide

[Bis(methylthio)methylene]malononitrile
5147-80-8

[Bis(methylthio)methylene]malononitrile

Conditions
ConditionsYield
In ice-water
In methanol
In ethanol at 20℃;
potassium 1,1-dicyanoethylene-2,2-ditholate
4777-48-4

potassium 1,1-dicyanoethylene-2,2-ditholate

dimethyl sulfate
77-78-1

dimethyl sulfate

[Bis(methylthio)methylene]malononitrile
5147-80-8

[Bis(methylthio)methylene]malononitrile

Conditions
ConditionsYield
In water
dimercaptomethylene-malononitrile
18771-14-7

dimercaptomethylene-malononitrile

methyl iodide
74-88-4

methyl iodide

[Bis(methylthio)methylene]malononitrile
5147-80-8

[Bis(methylthio)methylene]malononitrile

Conditions
ConditionsYield
With tetrabutylammomium bromide In N,N-dimethyl-formamide at 60℃; for 64h; Inert atmosphere;3.4 g
In dimethyl sulfoxide at 5 - 20℃; for 12h;18.2 g
carbon disulfide
75-15-0

carbon disulfide

methyl iodide
74-88-4

methyl iodide

1,3-dicyano-1,3-propanedione

1,3-dicyano-1,3-propanedione

[Bis(methylthio)methylene]malononitrile
5147-80-8

[Bis(methylthio)methylene]malononitrile

Conditions
ConditionsYield
Stage #1: carbon disulfide; 1,3-dicyano-1,3-propanedione With potassium carbonate In N,N-dimethyl-formamide at 0 - 20℃; for 0.5h;
Stage #2: methyl iodide In N,N-dimethyl-formamide at 20℃; for 8.25h;
[Bis(methylthio)methylene]malononitrile
5147-80-8

[Bis(methylthio)methylene]malononitrile

benzylamine
100-46-9

benzylamine

2-benzylamino-2-methylthio-1,1-ethylenedicarbonitrile
152588-23-3

2-benzylamino-2-methylthio-1,1-ethylenedicarbonitrile

Conditions
ConditionsYield
at 20℃;100%
Heating;
In ethyl acetate
4-piperidinopiperidin
4897-50-1

4-piperidinopiperidin

[Bis(methylthio)methylene]malononitrile
5147-80-8

[Bis(methylthio)methylene]malononitrile

[(methylthio)(4-piperidinopiperidino)methylene]malononitrile
904677-87-8

[(methylthio)(4-piperidinopiperidino)methylene]malononitrile

Conditions
ConditionsYield
In tetrahydrofuran at 0 - 20℃; for 0.25h;100%
C18H18N2O

C18H18N2O

[Bis(methylthio)methylene]malononitrile
5147-80-8

[Bis(methylthio)methylene]malononitrile

C23H20N4OS

C23H20N4OS

Conditions
ConditionsYield
In xylene Heating;100%
9-amino-9-deoxy-epihydroquinine
852913-53-2

9-amino-9-deoxy-epihydroquinine

[Bis(methylthio)methylene]malononitrile
5147-80-8

[Bis(methylthio)methylene]malononitrile

C25H29N5OS

C25H29N5OS

Conditions
ConditionsYield
In tetrahydrofuran for 24h; Reflux;100%
[Bis(methylthio)methylene]malononitrile
5147-80-8

[Bis(methylthio)methylene]malononitrile

propan-1-ol-3-amine
156-87-6

propan-1-ol-3-amine

[1-(1-benzylpiperidin-4-ylamino)-2-(3-hydroxypropylamino)methylene]malononitrile
904678-69-9

[1-(1-benzylpiperidin-4-ylamino)-2-(3-hydroxypropylamino)methylene]malononitrile

Conditions
ConditionsYield
Stage #1: 4-amino-1-benzylpiperidine; [Bis(methylthio)methylene]malononitrile In tetrahydrofuran at 20℃; for 2.5h;
Stage #2: propan-1-ol-3-amine In tetrahydrofuran at 60℃; for 16h;
99.5%
[Bis(methylthio)methylene]malononitrile
5147-80-8

[Bis(methylthio)methylene]malononitrile

dibutylamine
111-92-2

dibutylamine

2-(Dibutylamino-methylsulfanyl-methylene)-malononitrile
85106-65-6

2-(Dibutylamino-methylsulfanyl-methylene)-malononitrile

Conditions
ConditionsYield
In benzene Ambient temperature;99%
In dichloromethane Heating;
[Bis(methylthio)methylene]malononitrile
5147-80-8

[Bis(methylthio)methylene]malononitrile

Methyl thioglycolate
2365-48-2

Methyl thioglycolate

methyl 3-amino-4-cyano-5-(methylsulfanyl)-2-thiophenecarboxylate
129332-45-2

methyl 3-amino-4-cyano-5-(methylsulfanyl)-2-thiophenecarboxylate

Conditions
ConditionsYield
With triethylamine In methanol for 2h; Reflux;99%
With triethylamine In methanol for 1h; Heating;84%
With triethylamine In methanol at 130℃; for 0.0666667h; Microwave irradiation;82%
With triethylamine In methanol
m-Anisidine
536-90-3

m-Anisidine

[Bis(methylthio)methylene]malononitrile
5147-80-8

[Bis(methylthio)methylene]malononitrile

2-cyano-3-(3-methoxyphenylamino)-3-methylsulfanylacrylonitrile
155557-30-5

2-cyano-3-(3-methoxyphenylamino)-3-methylsulfanylacrylonitrile

Conditions
ConditionsYield
In methanol for 15h; Heating;99%
With 4-methoxy-aniline at 100℃; for 2h;70%
Heating;
Stage #1: m-Anisidine; [Bis(methylthio)methylene]malononitrile In pyridine for 1h; Reflux;
Stage #2: In pyridine
[Bis(methylthio)methylene]malononitrile
5147-80-8

[Bis(methylthio)methylene]malononitrile

ethyl 2-sulfanylacetate
623-51-8

ethyl 2-sulfanylacetate

3-amino-4-cyano-5-(methylthio)thiophene-2-carboxylic acid ethyl ester
116170-90-2

3-amino-4-cyano-5-(methylthio)thiophene-2-carboxylic acid ethyl ester

Conditions
ConditionsYield
With triethylamine In methanol for 2h; Reflux;99%
With triethylamine In methanol for 2h; Reflux;99%
With triethylamine In ethanol at 0 - 20℃; for 12h;72.6%
[Bis(methylthio)methylene]malononitrile
5147-80-8

[Bis(methylthio)methylene]malononitrile

phosphonic acid diethyl ester
762-04-9

phosphonic acid diethyl ester

(2,2-Dicyano-1-methylsulfanyl-vinyl)-phosphonic acid diethyl ester
194095-91-5

(2,2-Dicyano-1-methylsulfanyl-vinyl)-phosphonic acid diethyl ester

Conditions
ConditionsYield
With sodium hydride In tetrahydrofuran99%
Cyanothioacetamide
7357-70-2

Cyanothioacetamide

[Bis(methylthio)methylene]malononitrile
5147-80-8

[Bis(methylthio)methylene]malononitrile

2-amino-6-mercapto-4-(methylthio)pyridine-3,5-dicarbonitrile

2-amino-6-mercapto-4-(methylthio)pyridine-3,5-dicarbonitrile

Conditions
ConditionsYield
With triethylamine In N,N-dimethyl-formamide at 20℃;99%
With triethylamine In N,N-dimethyl-formamide at 20℃; for 18h;93%
With triethylamine In N,N-dimethyl-formamide at 20℃;89%
[Bis(methylthio)methylene]malononitrile
5147-80-8

[Bis(methylthio)methylene]malononitrile

phenylhydrazine
100-63-0

phenylhydrazine

5-amino-3-(methylsulfanyl)-1-phenyl-1H-pyrazole-4-carbonitrile
59334-11-1

5-amino-3-(methylsulfanyl)-1-phenyl-1H-pyrazole-4-carbonitrile

Conditions
ConditionsYield
In methanol Heating;98%
for 3h; Reflux;96%
In ethanol
In ethanol Heating;
In ethanol
4-(2-methylpyrrolidin-1-ylmethyl)piperidine dihydrochloride

4-(2-methylpyrrolidin-1-ylmethyl)piperidine dihydrochloride

[Bis(methylthio)methylene]malononitrile
5147-80-8

[Bis(methylthio)methylene]malononitrile

{[4-(2-methylpyrrolidin-1-ylmethyl)piperidino](methylthio)methylene}malononitrile
904677-53-8

{[4-(2-methylpyrrolidin-1-ylmethyl)piperidino](methylthio)methylene}malononitrile

Conditions
ConditionsYield
With sodium hydroxide In tetrahydrofuran; water at 0 - 20℃; for 0.25h;98%
[Bis(methylthio)methylene]malononitrile
5147-80-8

[Bis(methylthio)methylene]malononitrile

3,5-bis-trifluoromethylbenzylamine
85068-29-7

3,5-bis-trifluoromethylbenzylamine

2-(((3,5-bis(trifluoromethyl)benzyl)amino)(methylthio)methylene)malononitrile
1598411-35-8

2-(((3,5-bis(trifluoromethyl)benzyl)amino)(methylthio)methylene)malononitrile

Conditions
ConditionsYield
In tetrahydrofuran for 23h; Reflux; Green chemistry; stereoselective reaction;98%
In methanol Reflux;
In tetrahydrofuran Reflux;
[Bis(methylthio)methylene]malononitrile
5147-80-8

[Bis(methylthio)methylene]malononitrile

5-amino-3-(methylsulfanyl)-1H-pyrazole-4-carbonitrile
72760-85-1

5-amino-3-(methylsulfanyl)-1H-pyrazole-4-carbonitrile

Conditions
ConditionsYield
With hydrazine hydrate In methanol for 3h; Heating;97%
With hydrazine hydrate In ethanol Cooling with ice; Reflux;85%
With hydrazine hydrate In methanol for 3h; Reflux;80%
[Bis(methylthio)methylene]malononitrile
5147-80-8

[Bis(methylthio)methylene]malononitrile

1,2-diamino-benzene
95-54-5

1,2-diamino-benzene

2-(2,3-dihydro-1H-benzo[d]imidazolylidene)malononitrile
4933-40-8

2-(2,3-dihydro-1H-benzo[d]imidazolylidene)malononitrile

Conditions
ConditionsYield
In ethanol for 24h; Heating;97%
Stage #1: [Bis(methylthio)methylene]malononitrile; 1,2-diamino-benzene In ethanol for 8h; Reflux;
Stage #2: With sodium ethanolate; N-Cyanoguanidine In ethanol for 5h; Reflux;
84%
In ethanol at 70℃; for 4h;77.6%
In ethanol for 24h; Heating;
4-(N-methyl-N-phenylamino)piperidine dihydrochloride

4-(N-methyl-N-phenylamino)piperidine dihydrochloride

[Bis(methylthio)methylene]malononitrile
5147-80-8

[Bis(methylthio)methylene]malononitrile

{[4-(N-methyl-N-phenylamino)piperidino](methylthio)methylene}malononitrile
904677-47-0

{[4-(N-methyl-N-phenylamino)piperidino](methylthio)methylene}malononitrile

Conditions
ConditionsYield
With sodium hydroxide In tetrahydrofuran; water at 20℃; for 0.25h;97%
[Bis(methylthio)methylene]malononitrile
5147-80-8

[Bis(methylthio)methylene]malononitrile

Trimethylenediamine
109-76-2

Trimethylenediamine

2-(hexahydropyrimidin-2-ylidene)malononitrile

2-(hexahydropyrimidin-2-ylidene)malononitrile

Conditions
ConditionsYield
In water at 25℃; regioselective reaction;97%
85%
1-phenyl-2-pyridin-2-ylethanone
1620-53-7

1-phenyl-2-pyridin-2-ylethanone

[Bis(methylthio)methylene]malononitrile
5147-80-8

[Bis(methylthio)methylene]malononitrile

1-Benzoyl-4-imino-2-methylsulfanyl-4H-quinolizine-3-carbonitrile
123366-01-8

1-Benzoyl-4-imino-2-methylsulfanyl-4H-quinolizine-3-carbonitrile

Conditions
ConditionsYield
With potassium carbonate In dimethyl sulfoxide Ambient temperature;96%
N-trimethylsilylmethylamine
18166-02-4

N-trimethylsilylmethylamine

[Bis(methylthio)methylene]malononitrile
5147-80-8

[Bis(methylthio)methylene]malononitrile

2-[Methylsulfanyl-(trimethylsilanylmethyl-amino)-methylene]-malononitrile
129757-45-5

2-[Methylsulfanyl-(trimethylsilanylmethyl-amino)-methylene]-malononitrile

Conditions
ConditionsYield
In methanol for 0.166667h; Heating;96%
1-methyl-3-(2-ethoxy-2-oxoethyl)-1H-imidazol-3-ium bromide
109833-18-3

1-methyl-3-(2-ethoxy-2-oxoethyl)-1H-imidazol-3-ium bromide

[Bis(methylthio)methylene]malononitrile
5147-80-8

[Bis(methylthio)methylene]malononitrile

1-methylimidazolium N-(3,3-dicyano-1-ethoxycarbonyl-2-methylthio)allylide
139038-43-0

1-methylimidazolium N-(3,3-dicyano-1-ethoxycarbonyl-2-methylthio)allylide

Conditions
ConditionsYield
With potassium carbonate In chloroform for 168h; Ambient temperature;96%
[Bis(methylthio)methylene]malononitrile
5147-80-8

[Bis(methylthio)methylene]malononitrile

Cysteamine
60-23-1

Cysteamine

2-(thiazolidin-2-ylidene)malononitrile
5718-93-4

2-(thiazolidin-2-ylidene)malononitrile

Conditions
ConditionsYield
In ethanol for 2h; Heating;96%
In ethanol at 20℃; for 4h;73%
In water Reflux; regioselective reaction;73%
In ethanol at 20℃; for 4h;73%
In ethanol at 20℃; for 4h;
N,N'-bis(2-hydroxyethyl)ethylene diamine
4439-20-7

N,N'-bis(2-hydroxyethyl)ethylene diamine

[Bis(methylthio)methylene]malononitrile
5147-80-8

[Bis(methylthio)methylene]malononitrile

[1,3-bis(2-hydroxyethyl)imidazolidin-2-ylidene]malononitrile
111161-06-9

[1,3-bis(2-hydroxyethyl)imidazolidin-2-ylidene]malononitrile

Conditions
ConditionsYield
In tetrahydrofuran for 1h; Heating;95.3%
In methanol for 14h; Heating;92%
N,N-bis(2-hydroxyethyl)ethylidenediamine
3197-06-6

N,N-bis(2-hydroxyethyl)ethylidenediamine

[Bis(methylthio)methylene]malononitrile
5147-80-8

[Bis(methylthio)methylene]malononitrile

[1,3-bis(2-hydroxyethyl)imidazolidin-2-ylidene]malononitrile
111161-06-9

[1,3-bis(2-hydroxyethyl)imidazolidin-2-ylidene]malononitrile

Conditions
ConditionsYield
In tetrahydrofuran for 1h; Heating / reflux;95.3%
[Bis(methylthio)methylene]malononitrile
5147-80-8

[Bis(methylthio)methylene]malononitrile

2-(2-Aminoethylamino)ethanol
111-41-1

2-(2-Aminoethylamino)ethanol

<1-(2-hydroxyethyl)-2-imidazolidinylidene>malononitrile
149138-82-9

<1-(2-hydroxyethyl)-2-imidazolidinylidene>malononitrile

Conditions
ConditionsYield
In tetrahydrofuran at 0 - 20℃; for 3h;95.2%
In tetrahydrofuran at 20℃; for 2h;95%
In toluene for 20h; Ambient temperature;90%
[Bis(methylthio)methylene]malononitrile
5147-80-8

[Bis(methylthio)methylene]malononitrile

2-amino-benzenethiol
137-07-5

2-amino-benzenethiol

(2,3-dihydrobenzothiazol-2-ylidenyl)malonodinitrile
4464-52-2

(2,3-dihydrobenzothiazol-2-ylidenyl)malonodinitrile

Conditions
ConditionsYield
In ethanol for 24h; Heating;95%
In ethanol for 6h; Heating;90%
With piperidine In ethanol for 5h; Heating;52%
[Bis(methylthio)methylene]malononitrile
5147-80-8

[Bis(methylthio)methylene]malononitrile

methylhydrazine
60-34-4

methylhydrazine

1H-1-methyl-3-amino-4-cyano-5-methylsulfanylpyrazole
151291-05-3

1H-1-methyl-3-amino-4-cyano-5-methylsulfanylpyrazole

Conditions
ConditionsYield
In ethanol for 6h; Heating;95%
In ethanol for 1h; Heating;40%
In water
In water
Heating / reflux;
[Bis(methylthio)methylene]malononitrile
5147-80-8

[Bis(methylthio)methylene]malononitrile

4-((4-methoxyphenyl)diazenyl)-1H-pyrazole-3,5-diamine
6975-75-3

4-((4-methoxyphenyl)diazenyl)-1H-pyrazole-3,5-diamine

2,5-diamino-3-((4-methoxyphenyl)diazenyl)-7-(methylthio)pyrazolo[1,5-a]pyrimidine-6-carbonitrile
155375-48-7

2,5-diamino-3-((4-methoxyphenyl)diazenyl)-7-(methylthio)pyrazolo[1,5-a]pyrimidine-6-carbonitrile

Conditions
ConditionsYield
In N,N-dimethyl-formamide at 154℃; for 0.166667h; Microwave irradiation;95%
With piperidine In ethanol for 4h; Heating;85%
[Bis(methylthio)methylene]malononitrile
5147-80-8

[Bis(methylthio)methylene]malononitrile

3,5-diamino-4-phenylazopyrazole
3656-02-8

3,5-diamino-4-phenylazopyrazole

2, 5-diamino-7-(methylthio)-3-(phenyldiazenyl)pyrazolo[1,5-a]pyrimidine-6-carbonitrile
155375-38-5

2, 5-diamino-7-(methylthio)-3-(phenyldiazenyl)pyrazolo[1,5-a]pyrimidine-6-carbonitrile

Conditions
ConditionsYield
In N,N-dimethyl-formamide at 154℃; for 0.166667h; Microwave irradiation;95%
With piperidine In ethanol for 4h; Heating;90%

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