Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities
Cas:549-18-8
Min.Order:1 Kilogram
FOB Price: $3.0
Type:Lab/Research institutions
inquiryHangzhou Dingyan Chem is a leading manufacturer and supplier of chemicals in China.We develop,produce and distribute high quality pharmaceuticals, intermediates, special chemicals and other fine chemicals. -------------------------------------
Cas:549-18-8
Min.Order:1 Kilogram
FOB Price: $1300.0 / 1600.0
Type:Trading Company
inquiryhigh quality Appearance:White or off-white Solid Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea Port:shanghai
The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi
CAS RN.: 549-18-8 EINECS: 208-964-6 Molecular Weight:
Cas:549-18-8
Min.Order:10 Kilogram
Negotiable
Type:Trading Company
inquiry1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s
Cas:549-18-8
Min.Order:1 Gram
FOB Price: $0.1
Type:Manufacturers
inquiryOur main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block
Cas:549-18-8
Min.Order:5 Kiloliter
FOB Price: $1.2 / 5.0
Type:Manufacturers
inquiryWhy is SINOWAY: 1) Specialized in pharmaceutical and healthcare industrial for 34 years. 2) ISO 9001:2015 & SGS audited supplier . 3) Accept various payment terms : T.T 30-60 days. 4) We have warehouse in USA with quickly shipment . 5) We c
Cas:549-18-8
Min.Order:1 Kilogram
FOB Price: $50.0
Type:Trading Company
inquiryAmitriptyline hydrochloride Basic information Product Name: Amitriptyline hydrochloride Synonyms: 10,11-dihydro-n,n-dimethyl-5h-dibenzo(a,d)cycloheptene-delta(sup5,
Cas:549-18-8
Min.Order:1 Metric Ton
Negotiable
Type:Lab/Research institutions
inquiryOur advantages: 1. All inquiries will be replied within 12 hours. 2. Dedication to quality, supply & service. 3. Strictly on selecting raw materials. 4. Reasonable & competitive price, fast lead time. 5. Sample is available for your eva
Cas:549-18-8
Min.Order:1 Kilogram
FOB Price: $9.0 / 99.0
Type:Trading Company
inquiryWITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et
Cas:549-18-8
Min.Order:1 Kilogram
FOB Price: $139.0 / 210.0
Type:Trading Company
inquiryAdvantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the R&
Cas:549-18-8
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryProduct Name Amitriptyline hydrochloride CAS NO 549-18-8 Appearance White crystalline powder Molecular Formula C20H24ClN Molecular weight 31
1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; Appearance:White crystalline granules or powder. Storage:Store in seale
Cas:549-18-8
Min.Order:100 Gram
Negotiable
Type:Other
inquiry1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized
Cas:549-18-8
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryWe are the manufacturers and suppliers of API in China, and warehouse in Germany and USA of California, which can quickly and safely deliver to your address 1.High quality and competitive price. 2.Free sample for your evaluation. 3.Promptly delivery
Cas:549-18-8
Min.Order:10 Gram
FOB Price: $3.5
Type:Trading Company
inquiryAmitriptyline hydrochloride Basic information Overview Pharmacokinetics Indication Mode of action Adverse reactions Precautions Reference Product Name: Amitriptyline hydrochloride Synonyms: Amiplin;Normaln;Amitriptyline Hydrochloride (200 mg);M
Cas:549-18-8
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryOur company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At present,
Cas:549-18-8
Min.Order:1 Kilogram
FOB Price: $1050.0
Type:Trading Company
inquiryAmitriptyline hydrochloride CAS:549-18-8 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic
Cas:549-18-8
Min.Order:1 Gram
Negotiable
Type:Lab/Research institutions
inquiryWe have overseas warehouses in California, New Laredo Mexico, Vancouver Canada, Amsterdam Netherlands, and Melbourne Australia. Overseas warehouses can provide some of the best-selling products. We look forward to the cooperation of local powerful
Cas:549-18-8
Min.Order:0 Metric Ton
Negotiable
Type:Trading Company
inquiryHello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai
Cas:549-18-8
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryHenan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod
Cas:549-18-8
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryOur Services 1. New Molecules R&D 2. Own test center HPLC NMR GC LC-MS 3. API and Intermediates from China reputed manufacturers 4. Documents support COA MOA MSDS DMF open part Our advantages 1. Government awarded company. Top 100 enter
Cas:549-18-8
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryOur Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We
Cas:549-18-8
Min.Order:10 Kilogram
Negotiable
Type:Trading Company
inquiry≥99.0% conform to the CP2010. Appearance:A white to almost white powder or colorless crystals Storage:Room temperature Package:25kg/drum or as required Application:used in medicine Transportation:by sea by air express Port:China main port
Cas:549-18-8
Min.Order:1 Kilogram
Negotiable
Type:Trading Company
inquiryOur Advantages Production: Advanced chemical equipment with years of experience Staffs for producing various extract products. Quality Control:A complete set of Testing Professional and Analysis Equipment ensures the Quality Requirements and Specif
Cas:549-18-8
Min.Order:1 Kilogram
FOB Price: $75.0 / 150.0
Type:Trading Company
inquiryJ&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia
Cas:549-18-8
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryZibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi
Cas:549-18-8
Min.Order:10 Gram
FOB Price: $100.0
Type:Lab/Research institutions
inquiryWe are one of a few suppliers that can offer custom synthesis service of this product We are specialized in custom synthesis, chemical/pharmaceutical/ pesticides outsourcing and contract research. We are committed to prov
Cas:549-18-8
Min.Order:100 Gram
FOB Price: $100.0 / 2000.0
Type:Lab/Research institutions
inquirysupplier in China Appearance:white crystalline powder Storage:Stored in cool, dry and ventilation place; Away from fire and heat Package:100g/bottle,1kg/bottle,25kg/drum or as per your request Application:Antidepressant. Transportation:BY SEA P
Cas:549-18-8
Min.Order:1 Kilogram
Negotiable
Type:Trading Company
inquiry5-(3-dimethylaminopropyl)-10,11-dihydrodibenzo[a,d]cyclohepten-5-ol
amitriptyline hydrochloride
Conditions | Yield |
---|---|
With hydrogenchloride In ethanol Heating; | 63% |
Multi-step reaction with 2 steps 1: ethanol / 0.01 h / 200 °C / 82508.3 Torr / Flow reactor 2: hydrogenchloride / isopropyl alcohol / 20 °C / Flow reactor View Scheme |
10,11-Dihydro-5H-dibenzo[a,d]cyclohepten-5-one
3-(Dimethylamino)propyl chloride
amitriptyline hydrochloride
Conditions | Yield |
---|---|
With hydrogenchloride; 1,1-Dibromoethane; magnesium 1) THF, reflux; 2) THF, reflux;; Yield given. Multistep reaction; |
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1.1: magnesium; I2 / tetrahydrofuran / Heating 1.2: 68 percent / tetrahydrofuran / 0 - 20 °C 2.1: 63 percent / aq. HCl / ethanol / Heating View Scheme | |
Multi-step reaction with 3 steps 1: methanol / tetrahydrofuran; toluene / 20 °C / Flow reactor 2: ethanol / 0.01 h / 200 °C / 82508.3 Torr / Flow reactor 3: hydrogenchloride / isopropyl alcohol / 20 °C / Flow reactor View Scheme |
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1.1: magnesium; I2 / tetrahydrofuran / Heating 1.2: 68 percent / tetrahydrofuran / 0 - 20 °C 2.1: 63 percent / aq. HCl / ethanol / Heating View Scheme |
Conditions | Yield |
---|---|
With hydrogenchloride In isopropyl alcohol at 20℃; Flow reactor; |
Conditions | Yield |
---|---|
Multi-step reaction with 4 steps 1: n-butyllithium; carbon dioxide / tetrahydrofuran; hexane / -50 - 20 °C / 3878.71 Torr / Flow reactor 2: methanol / tetrahydrofuran; toluene / 20 °C / Flow reactor 3: ethanol / 0.01 h / 200 °C / 82508.3 Torr / Flow reactor 4: hydrogenchloride / isopropyl alcohol / 20 °C / Flow reactor View Scheme | |
Multi-step reaction with 4 steps 1: n-butyllithium; carbon dioxide / tetrahydrofuran; hexane / -50 - 20 °C / Flow reactor 2: methanol / tetrahydrofuran; toluene / 20 °C / Flow reactor 3: ethanol / 0.01 h / 200 °C / 82508.3 Torr / Flow reactor 4: hydrogenchloride / isopropyl alcohol / 20 °C / Flow reactor View Scheme |
amitriptyline hydrochloride
A
3-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N-methyl-1-propanamine
B
10-Hydroxynortriptyline
C
(Z)-10-Hydroxyamitriptyline
Conditions | Yield |
---|---|
With glucose dehydrogenase; D-glucose; cytochrome P450BM3 F87A/H171L/Q307H/N319Y mutant; oxygen; β-nicotinamide adenine dinucleotide phosphate sodium salt In ethanol at 25℃; for 2h; pH=8.5; Enzymatic reaction; | A 69% B n/a C n/a |
Conditions | Yield |
---|---|
With potassium carbonate In N,N-dimethyl-formamide at 80℃; Inert atmosphere; | 26% |
amitriptyline hydrochloride
5-(3-N,N-dimethylaminopropyl)-10,11-dihydro-5H-dibenzocycloheptene
Conditions | Yield |
---|---|
With perchloric acid; hydrogen; platinum(IV) oxide |
Conditions | Yield |
---|---|
With hydrogenchloride; iron(III) chloride In water at 30℃; for 0.25h; Condensation; |
amitriptyline hydrochloride
2,4,6-Trinitrophenol
3-(10,11-dihydro-5H-dibenzo[a,d][7]annulen-5-ylidene)-N,N-dimethylpropan-1-aminium 2,4,6-trinitrophenolate
Conditions | Yield |
---|---|
In water at 20℃; |
amitriptyline hydrochloride
Conditions | Yield |
---|---|
With nitric acid; ascorbic acid In water addn. of soln. of molybdenum (VI) to HNO3, NH4SCN and ascorbic acid; standing at 20°C for 15 min; addn. of amitriptyline hydrochloride; dilution with H2O; standing for 15 min; extn. with CH2Cl2 with shaking for 1 min; filtration, monitoring by UV; | |
With hydrogenchloride; ascorbic acid In water Kinetics; addn. of soln. of molybdenum (VI) to HCl, NH4SCN and ascorbic acid; standing at 20°C for 15 min; addn. of amitriptyline hydrochloride; dilution with H2O; standing for 15 min; extn. with CH2Cl2 with shaking for 1 min; filtration, monitoring by UV; | |
With sulfuric acid; ascorbic acid In water addn. of soln. of molybdenum (VI) to H2SO4, NH4SCN and ascorbic acid; standing at 20°C for 15 min; addn. of amitriptyline hydrochloride; dilution with H2O; standing for 15 min; extn. with CH2Cl2 with shaking for 1 min; filtration, monitoring by UV; |
Conditions | Yield |
---|---|
With potassium permanganate; sodium hydroxide In water at 25℃; Kinetics; |
Conditions | Yield |
---|---|
In aq. acetate buffer at 25℃; pH=3.8; pH-value; Solvent; Concentration; Temperature; |
amitriptyline hydrochloride
A
3-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N-methyl-1-propanamine
B
(Z)-10-Hydroxyamitriptyline
Conditions | Yield |
---|---|
With glucose dehydrogenase; D-glucose; cytochrome P450BM3 R47L/Y51F/V78I/A191T/N239H/I259V/A276T/A330P/L353I mutant; oxygen; β-nicotinamide adenine dinucleotide phosphate sodium salt In ethanol at 25℃; for 2h; pH=8.5; Enzymatic reaction; | A n/a B 18.7 mg |
amitriptyline hydrochloride
A
3-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N-methyl-1-propanamine
B
Desmethylnortriptyline
Conditions | Yield |
---|---|
With glucose dehydrogenase; D-glucose; cytochrome P450BM3 R47L/Y51F/A191T/N239H/I259V/A276T/P329V/A330P/L353I mutant; oxygen; β-nicotinamide adenine dinucleotide phosphate sodium salt In ethanol at 25℃; for 2h; pH=8.5; Enzymatic reaction; |
amitriptyline hydrochloride
3-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N-methyl-1-propanamine
Conditions | Yield |
---|---|
With glucose dehydrogenase; D-glucose; cytochrome P450BM3 R47L/Y51F/F87V/E267V/I401P mutant; oxygen; β-nicotinamide adenine dinucleotide phosphate sodium salt In ethanol at 25℃; for 2h; pH=8.5; Enzymatic reaction; |
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