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Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch

Staurosporine Manufacturer/High quality/Best price/In stock

Cas:62996-74-1

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Sinoway Industrial Co., Ltd.

We are very compeitive on Midostaurin .Our mfr is Chinese GMP certified for this item with DMF/CEP document. It has a great function of potassium-sparing diuretics. our advantage of Midostaurin USP/EP/CEP Stable supply. Product Na

factory supply Midostaurin intermediate Staurosporine

Cas:62996-74-1

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

Hebei Nengqian Chemical Import and Export Co., LTD

Our advantages: 1. All inquiries will be replied within 12 hours. 2. Dedication to quality, supply & service. 3. Strictly on selecting raw materials. 4. Reasonable & competitive price, fast lead time. 5. Sample is available for your eva

STAUROSPORINE

Cas:62996-74-1

Min.Order:1 Kilogram

FOB Price: $9.0 / 99.0

Type:Trading Company

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Pharmaceutical Grade CAS 62996-74-1 with competitive price

Cas:62996-74-1

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

HANWAYS CHEMPHARM CO.,LIMITED

Hanways chempharm is a specialized company concentrating on the R&D, production, marketing and technical service of APIs and pharmaceutical intermediates. The marketing department is located in Wuhan. We have two GMP facilities in Hubei Pr

High Quality Antifungal Agent Powder CAS 62996-74-1 Staurosporine

Cas:62996-74-1

Min.Order:1 Kilogram

FOB Price: $200.0 / 400.0

Type:Trading Company

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

Qingdao Beluga Import and Export Co., LTD

STAUROSPORINE CAS:62996-74-1 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic intermediat

STAUROSPORINE CAS:62996-74-1

Cas:62996-74-1

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

LIDE PHARMACEUTICALS LIMITED

Advantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the R&amp

Hangzhou JINLAN Pharm-Drugs Technology Co., Ltd

We can provide GMP validation service that complies with SFDA, FDA, WHO and EU EMPA.Excellent registration team could help us easlily to register our products in different countries.If you and your customer are interested in some products or need C

STAUROSPORINE manufacturer with low price

Cas:62996-74-1

Min.Order:1 Gram

Negotiable

Type:Trading Company

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

CAS NO.:62996-74-1

Cas:62996-74-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hubei CuiRan Biotechnology Co., Ltd

Hubei CuiRan Biotechnology Co., Ltd is a leading company in the research, development, manufacture and marketing of High Quality Phytochemicals and Extracts(especially Active Ingredients from Traditional Chinese Medicine,Traditional Chinese Medicine)

Staurosporine from Streptomyces sp

Cas:62996-74-1

Min.Order:10 Milligram

Negotiable

Type:Lab/Research institutions

inquiry

Triumph International Development Limilted

Triumph has the complete production of G- KG - MT service chain,we can make the new technology into productivity quickly in the research and development of new products. Main Business Custom Synthesis: Trading(Raw M

STAUROSPORINE

Cas:62996-74-1

Min.Order:0 Metric Ton

FOB Price: $18.0 / 20.0

Type:Lab/Research institutions

inquiry

Taizhou Crene Biotechnology co.ltd

Our company provides one-stop services of research - development - production for a variety of special prouducts. Not only do we make effective use of our strong technological strength, but also establish of cooperative relations with several well-

Staurosporine 62996-74-1

Cas:62996-74-1

Min.Order:100 Milligram

Negotiable

Type:Lab/Research institutions

inquiry

Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

Staurosporine 98%

Cas:62996-74-1

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

Staurosporine

Cas:62996-74-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply Staurosporine

Cas:62996-74-1

Min.Order:0 Metric Ton

Negotiable

Type:Other

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

Staurosporine

Cas:62996-74-1

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

TaiChem Taizhou Limited

Established in May 2015, TaiChem Ltd. is initially invested by a British research and development company and started by PhDs back from aboard. The company is registered in China Medical City (CMC), Taizhou, Jiangsu Province, and the production site

STAUROSPORINE

Cas:62996-74-1

Min.Order:10 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Zibo Dorne chemical technology co. LTD

Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,

STAUROSPORINE

Cas:62996-74-1

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Siwei Development Group Ltd.

Product name: Staurosporine CAS No.: 62996-74-1 Molecule Formula:C28H27N4O3 Molecule Weight:467.54 Purity: 99.0% Package: 25kg/drum Description:White powder Manufacture Standards:Enterprise Standard TESTING ITEMS

Lower Price Staurosporine

Cas:62996-74-1

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Jiangsu Qianyu Molecular Technology Co., LTD.

Our Advantages A. International Top level TechnologyOur company owned biomedicine experts are famous at home and abroad with rich experience in research and development in the field of efficient chiral functional molecules research and development an

Top Purity STAUROSPORINE

Cas:62996-74-1

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Xiamen Jenny Chemical Technology Co., Ltd.

GMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,

Henan Kanbei Chemical Co.,LTD

High quality, competitive price, fast delivery and first-class service we possesses have won the trust and praise of customers. Standard: BP/USP/EP The purity is equal or greater than 99%. As a supplier, we can provide high-quality products. Cle

Staurosporine from Streptomyces sp.;Antibiotic AM-2282.99%

Cas:62996-74-1

Min.Order:1 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

Staurosporine 98%

Cas:62996-74-1

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

inquiry

TAIZHOU ZHENYU BIOTECHNOLOGY CO., LTD

Zhenyu biotech exported this product to many countries and regions at best price. if you are looking for the material's manufacturer or supplier in china, zhenyu biotech is your best choice. pls contact with us freely for getting detailed

STAUROSPORINE

Cas:62996-74-1

Min.Order:1 Kilogram

FOB Price: $2.0

Type:Lab/Research institutions

inquiry

Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

STAUROSPORINE

Cas:62996-74-1

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

Staurosporine 98%

Cas:62996-74-1

Min.Order:1 Metric Ton

FOB Price: $1.5

Type:Trading Company

inquiry

Hunan chemfish Pharmaceutical co.,Ltd

Appearance:95%+ Package:R&D,Pilot run Transportation:per client require Port:Express ,Air, Sea

Staurosporine from streptomyces sp.

Cas:62996-74-1

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Synthetic route

C37H36N4O5
188028-33-3

C37H36N4O5

staurosporine
62996-74-1

staurosporine

Conditions
ConditionsYield
With methoxybenzene; trifluoroacetic acid for 48h;70%
With methoxybenzene; trifluoroacetic acid Yield given;
1-<(benzyloxy)methyl>-3,4-dihydro-4-(1H-indol-3-yl)-3-(1-<2-(trimethylsilyl)ethoxymethyl>-1H-indol-3-yl)-1H-pyrrole-2,5-dione
160256-37-1

1-<(benzyloxy)methyl>-3,4-dihydro-4-(1H-indol-3-yl)-3-(1-<2-(trimethylsilyl)ethoxymethyl>-1H-indol-3-yl)-1H-pyrrole-2,5-dione

6-(O-triisopropylsilyl)-L-glucal

6-(O-triisopropylsilyl)-L-glucal

A

C27H24N4O3
160256-55-3

C27H24N4O3

B

staurosporine
62996-74-1

staurosporine

Conditions
ConditionsYield
With Benzyloxymethyl chloride; thiophosgene; di-tert-butyl dicarbonate; 2,3,4,5,6-pentafluorophenol; trichloroacetonitrile; p-methoxybenzyl chloride; dimethyl sulfate In dichloromethaneA 39%
B 39%
7-carbonyl staurosporin

7-carbonyl staurosporin

A

staurosporine
62996-74-1

staurosporine

B

isostaurosporine

isostaurosporine

Conditions
ConditionsYield
With sodium tetrahydroborate; Benzeneselenol; toluene-4-sulfonic acid 1.) EtOH, RT, 2.) CH2Cl2, RT; Yield given. Multistep reaction. Yields of byproduct given;
C36H34N4O5
188028-11-7

C36H34N4O5

staurosporine
62996-74-1

staurosporine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 2.) BH3*DMS / 1) THF; 2) THF, toluene, reflux, 2 h
2: 70 percent / TFA, anisole / 48 h
View Scheme
Multi-step reaction with 2 steps
1: BH3*Me2S
2: CF3CO2H, anisole
View Scheme
C37H34N4O6
195617-12-0

C37H34N4O6

staurosporine
62996-74-1

staurosporine

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 79 mg / H2 / PtO2 / aq. acetic acid
2: 2.) BH3*DMS / 1) THF; 2) THF, toluene, reflux, 2 h
3: 70 percent / TFA, anisole / 48 h
View Scheme
Multi-step reaction with 3 steps
1: 96 percent / H2 / PtO2
2: BH3*Me2S
3: CF3CO2H, anisole
View Scheme
formaldehyd
50-00-0

formaldehyd

staurosporine
62996-74-1

staurosporine

(5S,6R,7R,9R)-6-methoxy-5-methyl-7-(methylamino)-6,7,8,9,15,16-hexahydro-17-oxa-4b,9a,15-triaza-5,9-methanodibenzo[b,h]cyclonona[jkl]cyclopenta[e]-as-indacen-14(5h)-one
129623-30-9

(5S,6R,7R,9R)-6-methoxy-5-methyl-7-(methylamino)-6,7,8,9,15,16-hexahydro-17-oxa-4b,9a,15-triaza-5,9-methanodibenzo[b,h]cyclonona[jkl]cyclopenta[e]-as-indacen-14(5h)-one

Conditions
ConditionsYield
With sodium cyanoborohydride Methylation;100%
bromoacetic acid methyl ester
96-32-2

bromoacetic acid methyl ester

staurosporine
62996-74-1

staurosporine

methyl N-((5R,7R,8R,9S)-8-methoxy-9-methyl-16-oxo-6,7,8,9,15,16-hexahydro-5H,14H-17-oxa-4b,9a,15-triaza-5,9-methanodibenzo[b,h]cyclonona[jkl]cyclopenta[e]-as-indacen-7-yl)-N-methylglycinate

methyl N-((5R,7R,8R,9S)-8-methoxy-9-methyl-16-oxo-6,7,8,9,15,16-hexahydro-5H,14H-17-oxa-4b,9a,15-triaza-5,9-methanodibenzo[b,h]cyclonona[jkl]cyclopenta[e]-as-indacen-7-yl)-N-methylglycinate

Conditions
ConditionsYield
With potassium carbonate In tetrahydrofuran at 20℃; for 48h;97%
benzoyl chloride
98-88-4

benzoyl chloride

staurosporine
62996-74-1

staurosporine

N-benzoylstaurosporine

N-benzoylstaurosporine

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 0 - 5℃; for 0.5h;95%
With triethylamine In N,N-dimethyl-formamide Reagent/catalyst;
staurosporine
62996-74-1

staurosporine

2,2,2-Trichloroethyl chloroformate
17341-93-4

2,2,2-Trichloroethyl chloroformate

C31H27Cl3N4O5
135384-24-6

C31H27Cl3N4O5

Conditions
ConditionsYield
92%
With triethylamine In dichloromethane at 0 - 20℃;92%
succinic acid anhydride
108-30-5

succinic acid anhydride

staurosporine
62996-74-1

staurosporine

C32H30N4O6

C32H30N4O6

Conditions
ConditionsYield
Inert atmosphere;92%
With dmap In dimethyl sulfoxide at 20℃; for 30h;91%
With dmap In dimethyl sulfoxide Inert atmosphere;90%
benzoic acid anhydride
93-97-0

benzoic acid anhydride

staurosporine
62996-74-1

staurosporine

N-benzoylstaurosporine

N-benzoylstaurosporine

Conditions
ConditionsYield
In ethanol; water at 70℃; Product distribution / selectivity;91.5%
In ethanol; water at 70℃; Product distribution / selectivity;82%
In ethanol; dichloromethane at 26 - 40℃; for 35h; Solvent; Temperature;
staurosporine
62996-74-1

staurosporine

7-oxoylidenestaurosporine

7-oxoylidenestaurosporine

Conditions
ConditionsYield
With potassium tert-butylate; oxygen In dimethyl sulfoxide at 20℃; for 6h;88.6%
staurosporine
62996-74-1

staurosporine

7-carbonyl staurosporin

7-carbonyl staurosporin

Conditions
ConditionsYield
With potassium tert-butylate; oxygen In dimethyl sulfoxide at 20℃; for 6h;88.6%
staurosporine
62996-74-1

staurosporine

1,1'-carbonyldiimidazole
530-62-1

1,1'-carbonyldiimidazole

3'-N-(1H-imidazol-1-yl)carbonylstaurosporine

3'-N-(1H-imidazol-1-yl)carbonylstaurosporine

Conditions
ConditionsYield
In tetrahydrofuran for 12h; Reflux;84%
4-Fluorobenzenesulfonyl chloride
349-88-2

4-Fluorobenzenesulfonyl chloride

staurosporine
62996-74-1

staurosporine

3'-N-p-fluorobenzenesulfonylstaurosporine

3'-N-p-fluorobenzenesulfonylstaurosporine

Conditions
ConditionsYield
With triethylamine In dichloromethane at 20℃; for 4h; Inert atmosphere;83.3%
With triethylamine In dichloromethane at 20℃; for 4h; Inert atmosphere;83.3%
1,1'-Thiocarbonyldiimidazole
6160-65-2

1,1'-Thiocarbonyldiimidazole

staurosporine
62996-74-1

staurosporine

3'-N-(1-imidazolylthioformyl)staurosporine

3'-N-(1-imidazolylthioformyl)staurosporine

Conditions
ConditionsYield
With triethylamine In dichloromethane at 20℃; Inert atmosphere;82%
With triethylamine In dichloromethane at 20℃;78%
With triethylamine In dichloromethane at 20℃;78%
With triethylamine In dichloromethane at 20℃;78%
di-tert-butyl dicarbonate
24424-99-5

di-tert-butyl dicarbonate

staurosporine
62996-74-1

staurosporine

3'-N-(tert-butoxycarbonyl)staurosporine

3'-N-(tert-butoxycarbonyl)staurosporine

Conditions
ConditionsYield
With triethylamine In dichloromethane at 0℃; for 0.5h; Inert atmosphere;82%
With triethylamine In tetrahydrofuran at 10℃; for 0.5h;76%
1H-imidazole
288-32-4

1H-imidazole

bis(trichloromethyl) carbonate
32315-10-9

bis(trichloromethyl) carbonate

staurosporine
62996-74-1

staurosporine

3'-N-(1H-imidazol-1-yl)carbonylstaurosporine

3'-N-(1H-imidazol-1-yl)carbonylstaurosporine

Conditions
ConditionsYield
Stage #1: bis(trichloromethyl) carbonate; staurosporine With N-ethyl-N,N-diisopropylamine In tetrahydrofuran at 0 - 20℃; for 2h;
Stage #2: 1H-imidazole With dmap; N-ethyl-N,N-diisopropylamine In tetrahydrofuran at 60℃; for 2h;
80%
staurosporine
62996-74-1

staurosporine

chlorambucil
305-03-3

chlorambucil

3'-N-[4-[4-(N,N-bis(2-chloroethyl)amino)phenyl]butyryl]staurosporine

3'-N-[4-[4-(N,N-bis(2-chloroethyl)amino)phenyl]butyryl]staurosporine

Conditions
ConditionsYield
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 20℃; for 2h;80%
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 20℃; for 2h;80%
1H-imidazole
288-32-4

1H-imidazole

staurosporine
62996-74-1

staurosporine

3'-N-(1H-imidazol-1-yl)carbonylstaurosporine

3'-N-(1H-imidazol-1-yl)carbonylstaurosporine

Conditions
ConditionsYield
Stage #1: staurosporine With bis(trichloromethyl) carbonate; N-ethyl-N,N-diisopropylamine In tetrahydrofuran at 0 - 20℃; for 2h;
Stage #2: 1H-imidazole With dmap; N-ethyl-N,N-diisopropylamine In tetrahydrofuran at 60℃; for 2h;
80%
4-oxo-4-(prop-2-yn-1-ylamino)butanoic acid
342022-20-2

4-oxo-4-(prop-2-yn-1-ylamino)butanoic acid

staurosporine
62996-74-1

staurosporine

C35H33N5O5

C35H33N5O5

Conditions
ConditionsYield
With dmap; dicyclohexyl-carbodiimide56%
di-tert-butyl dicarbonate
24424-99-5

di-tert-butyl dicarbonate

staurosporine
62996-74-1

staurosporine

bis-Boc staurosporine

bis-Boc staurosporine

Conditions
ConditionsYield
With dmap; triethylamine In tetrahydrofuran at 25℃; for 48h; Inert atmosphere;55%
tert-butyl N-(2-(2-(2-(2-bromoethoxy)ethoxy)ethoxy)ethyl)carbamate

tert-butyl N-(2-(2-(2-(2-bromoethoxy)ethoxy)ethoxy)ethyl)carbamate

staurosporine
62996-74-1

staurosporine

tert-butyl 2-[[(5S,6R,7R,9R)-6-methoxy-5-methyl-14-oxo-6,7,8,9,15,16-hexahydro-5H,14H-5,9-epoxy-4b,9a,15-triazadibenzo[b,h]cyclonona[1,2,3,4-jkl]cyclopenta[e]-as-indacen-7-yl]-5,8,11-trioxa-2-azatridecan-13-yl]carbamate

tert-butyl 2-[[(5S,6R,7R,9R)-6-methoxy-5-methyl-14-oxo-6,7,8,9,15,16-hexahydro-5H,14H-5,9-epoxy-4b,9a,15-triazadibenzo[b,h]cyclonona[1,2,3,4-jkl]cyclopenta[e]-as-indacen-7-yl]-5,8,11-trioxa-2-azatridecan-13-yl]carbamate

Conditions
ConditionsYield
With potassium carbonate; potassium iodide In N,N-dimethyl-formamide at 80℃; for 17h;50%
bromocyane
506-68-3

bromocyane

staurosporine
62996-74-1

staurosporine

3'-N-cyanostauroporine
1415406-02-8

3'-N-cyanostauroporine

Conditions
ConditionsYield
Stage #1: staurosporine With potassium carbonate In tetrahydrofuran at 20℃; for 0.25h;
Stage #2: bromocyane In tetrahydrofuran at 20℃; for 3h;
38%
bis(trichloromethyl) carbonate
32315-10-9

bis(trichloromethyl) carbonate

staurosporine
62996-74-1

staurosporine

KIST301135
1326539-88-1

KIST301135

Conditions
ConditionsYield
With triethylamine In dichloromethane at 0 - 20℃; for 12h;13%
staurosporine
62996-74-1

staurosporine

methyl iodide
74-88-4

methyl iodide

4'-N-methylstaurosporine methiodide

4'-N-methylstaurosporine methiodide

Conditions
ConditionsYield
With tributyl-amine In N,N-dimethyl-formamide Ambient temperature;
staurosporine
62996-74-1

staurosporine

(+)-RK-286c
126572-73-4

(+)-RK-286c

Conditions
ConditionsYield
Multi-step reaction with 8 steps
1: 100 percent / NaBH3CN
2: 92 percent / m-chloroperoxybenzoic acid (m-CPBA) / CHCl3
3: 85 percent / 160 °C / 1 Torr
4: 65 percent / OsO4; N-methylmorpholine-N-oxide (NMO)
5: 60 percent / tetrahydrofuran
6: 47 percent / n-Bu3SnH; 2,2'-azobisisobutyronitrile (AIBN) / toluene
7: 80 percent
8: 50 percent / potassium tri-sec-butyl borohydride (K-Selectride)
View Scheme
staurosporine
62996-74-1

staurosporine

staurosporine
155416-34-5

staurosporine

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: 100 percent / NaBH3CN
2: 92 percent / m-chloroperoxybenzoic acid (m-CPBA) / CHCl3
3: 85 percent / 160 °C / 1 Torr
4: 65 percent / OsO4; N-methylmorpholine-N-oxide (NMO)
View Scheme
staurosporine
62996-74-1

staurosporine

3'-demethylamino-3'-oxostaurosporine
178276-05-6

3'-demethylamino-3'-oxostaurosporine

Conditions
ConditionsYield
Multi-step reaction with 7 steps
1: 100 percent / NaBH3CN
2: 92 percent / m-chloroperoxybenzoic acid (m-CPBA) / CHCl3
3: 85 percent / 160 °C / 1 Torr
4: 65 percent / OsO4; N-methylmorpholine-N-oxide (NMO)
5: 60 percent / tetrahydrofuran
6: 47 percent / n-Bu3SnH; 2,2'-azobisisobutyronitrile (AIBN) / toluene
7: 80 percent
View Scheme
staurosporine
62996-74-1

staurosporine

C27H21N3O3
169756-23-4

C27H21N3O3

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 100 percent / NaBH3CN
2: 92 percent / m-chloroperoxybenzoic acid (m-CPBA) / CHCl3
3: 85 percent / 160 °C / 1 Torr
View Scheme
staurosporine
62996-74-1

staurosporine

C27H23N3O3

C27H23N3O3

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1.1: 100 percent / NaBH3CN
2.1: 92 percent / m-chloroperoxybenzoic acid (m-CPBA) / CHCl3
3.1: 85 percent / 160 °C / 1 Torr
4.1: BH3
4.2: 80 percent / H2O2; NaOH
5.1: 58 percent / tetrahydrofuran
6.1: 63 percent / n-Bu3SnH; 2,2'-azobisisobutyronitrile (AIBN) / toluene
View Scheme
staurosporine
62996-74-1

staurosporine

C27H21N3O4
169756-27-8

C27H21N3O4

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1.1: 100 percent / NaBH3CN
2.1: 92 percent / m-chloroperoxybenzoic acid (m-CPBA) / CHCl3
3.1: 85 percent / 160 °C / 1 Torr
4.1: BH3
4.2: 80 percent / H2O2; NaOH
5.1: 88 percent
View Scheme

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