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Hebei yanxi chemical co.,LTD.

hebei yanxi chemical co., LTD who registered capital of 10 million yuan, nearly to $2 million, we have a pharmaceutical raw materials factory production of pharmaceutical raw materials, and a reagent r&d center, and we do research and developm

2(3H)-FURANONE,5-(1Z)-1-DECENYLDIHYDRO-,(5R)- CAS NO.64726-91-6

Cas:64726-91-6

Min.Order:1 Metric Ton

FOB Price: $1.0 / 3.0

Type:Trading Company

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Hebei Nengqian Chemical Import and Export Co., LTD

With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin

(R,Z)-5-(1-decenyl)dihydrofuran-2(3H)-one CAS 64726-91-6

Cas:64726-91-6

Min.Order:1 Kilogram

FOB Price: $3.0 / 10.0

Type:Trading Company

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Pharmaceutical Grade CAS 64726-91-6 with competitive price

Cas:64726-91-6

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

2(3H)-FURANONE,5-(1Z)-1-DECENYLDIHYDRO-,(5R)- CAS NO.64726-91-6

Cas:64726-91-6

Min.Order:10 Kilogram

FOB Price: $60.0 / 80.0

Type:Trading Company

inquiry

Shanghai Upbio Tech Co.,Ltd

1.In No Less 10 years exporting experience. you can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specializ

2(3H)-Furanone,5-(1Z)-1-decen-1-yldihydro-, (5R)-

Cas:64726-91-6

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Qingdao Beluga Import and Export Co., LTD

(R,Z)-5-(1-decenyl)dihydrofuran-2(3H)-one CAS:64726-91-6 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high

(R,Z)-5-(1-decenyl)dihydrofuran-2(3H)-one CAS:64726-91-6

Cas:64726-91-6

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

2(3H)-Furanone,5-(1Z)-1-decen-1-yldihydro-, (5R)-

Cas:64726-91-6

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

2(3H)-Furanone,5-(1Z)-1-decen-1-yldihydro-, (5R)-

Cas:64726-91-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Triumph International Development Limilted

Triumph has the complete production of G- KG - MT service chain,we can make the new technology into productivity quickly in the research and development of new products. Main Business Custom Synthesis: Trading(Raw Mater

(R,Z)-5-(1-decenyl)dihydrofuran-2(3H)-one

Cas:64726-91-6

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

High quality 2(3H)-Furanone,5-(1Z)-1-decen-1-yldihydro-, (5R)-

Cas:64726-91-6

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

SHANGHAI SYSTEAM BIOCHEM CO., LTD

We are one of a few suppliers that can offer custom synthesis service of this product We are specialized in custom synthesis, chemical/pharmaceutical/ pesticides outsourcing and contract research. We are committed to prov

2(3H)-FURANONE,5-(1Z)-1-DECENYLDIHYDRO-,(5R)- CAS NO.64726-91-6

Cas:64726-91-6

Min.Order:100 Gram

FOB Price: $100.0 / 2000.0

Type:Lab/Research institutions

inquiry

Jiangsu Qianyu Molecular Technology Co., LTD.

Our Advantages A. International Top level TechnologyOur company owned biomedicine experts are famous at home and abroad with rich experience in research and development in the field of efficient chiral functional molecules research and development an

Factory Sells(R,Z)-5-(1-decenyl)dihydrofuran-2(3H)-one

Cas:64726-91-6

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Xiamen Jenny Chemical Technology Co., Ltd.

GMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,

Japonilure

Cas:64726-91-6

Min.Order:1 Milligram

Negotiable

Type:Trading Company

inquiry

EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

2(3H)-FURANONE,5-(1Z)-1-DECENYLDIHYDRO-,(5R)- CAS NO.64726-91-6

Cas:64726-91-6

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

inquiry

Wuhan Circle Star Chem-medical Technology co.,Ltd.

1,we produce and sell good chemicals around the world. 2,our success rate is about 95%. this means, if customer order is accepted, the probability that the customer will obtain the ordered substances, is 95%. 3,our staff consists of highly qualified

(R,Z)-5-(1-decenyl)dihydrofuran-2(3H)-one

Cas:64726-91-6

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

2(3H)-FURANONE,5-(1Z)-1-DECENYLDIHYDRO-,(5R)- CAS NO.64726-91-6

Cas:64726-91-6

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

2(3H)-FURANONE,5-(1Z)-1-DECENYLDIHYDRO-,(5R)- CAS NO.64726-91-6

Cas:64726-91-6

Min.Order:1 Metric Ton

FOB Price: $1.5

Type:Trading Company

inquiry

Golden Pharma Co., Limited

GOLDEN PHARMA CO.,LIMITED.is a professional pharmaceutical company,our team have more than 20years expereince in pharmaceutical production and sales. we are a professional technical enterprise specializing in the R & D, production,QA regulation

(R,Z)-5-(1-decenyl)dihydrofuran-2(3H)-one

Cas:64726-91-6

Min.Order:1 Kilogram

Negotiable

Type:Other

inquiry

Bluecrystal chem-union

We are a Union of chemistry in China, consists of chemists,engineers, laboratories,factories in China. We organize surplus capacity of R&D and production as well as custom synthesis for chemical products and chemical business project. We are supp

2(3H)-FURANONE,5-(1Z)-1-DECENYLDIHYDRO-,(5R)- CAS NO.64726-91-6

Cas:64726-91-6

Min.Order:1 Metric Ton

FOB Price: $1.0

Type:Trading Company

inquiry

Hebei Mojin Biotechnology Co.,Ltd

We produce carbomer by our own factory,carbomer 940 is our best seller.It is used for cosmetic and medical.And we also become agent for lubrizol.Our carbomer 940 get high viscosity and good transparency.The price will depond on the market,surely supp

2(3H)-Furanone,5-(1Z)-1-decen-1-yldihydro-, (5R)-

Cas:64726-91-6

Min.Order:0

Negotiable

Type:Trading Company

inquiry

GIHI CHEMICALS CO.,LIMITED

Lower price, sample is available,SDS test documents are available,large stock in warehouseAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:Fine chemical intermediates, used as the main raw material for the synthe

2(3H)-FURANONE,5-(1Z)-1-DECENYLDIHYDRO-,(5R)- CAS NO.64726-91-6

Cas:64726-91-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Dingyan Chem Co., Ltd

R & D enterprises have their own stock in stock Package:1kg Application:pharmaceutical intermediates

2(3H)-Furanone,5-(1Z)-1-decen-1-yldihydro-, (5R)-

Cas:64726-91-6

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM is one of China's leading providers of integrated fine chemical services including offering, research and development, Custom manufacturing business, as well as other Value-added customer services, for diversified range products of chemicals

(R,Z)-5-(1-decenyl)dihydrofuran-2(3H)-one

Cas:64726-91-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Wuxi TAA Chemical Industry Co.,LTD.

1.A strong technical force and advanced processing equipments. The quality of the products has been strictly inspected and all kinds of index have reached or exceeded domestic and international standards.2. Now we have established long-term stable re

2(3H)-Furanone,5-(1Z)-1-decen-1-yldihydro-, (5R)-

Cas:64726-91-6

Min.Order:0

Negotiable

Type:Other

inquiry

Henan Tianfu Chemical Co., Ltd.

1.Our services:A.Supply sampleB.The packing also can be according the customers` requirmentC.Any inquiries will be replied within 24 hoursD.we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate.

2(3H)-Furanone,5-(1Z)-1-decen-1-yldihydro-, (5R)-

Cas:64726-91-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Xian Changyue Biological Technology Co., Ltd.

best seller Application:API

(R,Z)-5-(1-decenyl)dihydrofuran-2(3H)-one

Cas:64726-91-6

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Hebei Sankai Chemical Technology Co., Ltd

1. Product advantages? High purity, all above 98.5%, no impurities after dissolution? We will test each batch to ensure quality? OEM and private brand services designed for free? Various cap colors available? We can also provide MT1 peptide powder2.

(R,Z)-5-(1-decenyl)dihydrofuran-2(3H)-one

Cas:64726-91-6

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Antimex Chemical Limied

Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

2(3H)-Furanone,5-(1Z)-1-decen-1-yldihydro-, (5R)-

Cas:64726-91-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hubei Langyou International Trading Co., Ltd

2(3H)-FURANONE,5-(1Z)-1-DECENYLDIHYDRO-,(5R)- CAS NO.64726-91-6 Application:2(3H)-FURANONE,5-(1Z)-1-DECENYLDIHYDRO-,(5R)- CAS NO.64726-91-6

2(3H)-FURANONE,5-(1Z)-1-DECENYLDIHYDRO-,(5R)- CAS NO.64726-91-6

Cas:64726-91-6

Min.Order:0

Negotiable

Type:Other

inquiry

Guangdong Juda Chemical Industrial Co.,Limited

Factory supply high purity low priceAppearance:solid or liquid Storage:sealed in cool and dry place Package:As customer's requested Application:Pharma Intermediate Transportation:by courier/air/sea Port:Any port in China

Japonilure CAS No.64726-91-6

Cas:64726-91-6

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Synthetic route

(R)-(-)-5-(dec-1-ynyl)-tetrahydrofuran-2-one
72151-69-0

(R)-(-)-5-(dec-1-ynyl)-tetrahydrofuran-2-one

japonilure
64726-91-6

japonilure

Conditions
ConditionsYield
With quinoline; hydrogen; Lindlar's catalyst In pentane at 0℃; for 4h;94%
With quinoline; hydrogen; Lindlar's catalyst In pentane at 0℃; for 5h;91%
With quinoline; hydrogen; palladium on activated charcoal In pentane at 0℃; for 5h;91%
(R,Z)-methyl 4-hydroxytetradec-5-enoate

(R,Z)-methyl 4-hydroxytetradec-5-enoate

japonilure
64726-91-6

japonilure

Conditions
ConditionsYield
With toluene-4-sulfonic acid In dichloromethane at 0 - 25℃; Inert atmosphere;80%
(R)-((Z)-5-Dec-1-enyl)-tetrahydro-furan-2-ol

(R)-((Z)-5-Dec-1-enyl)-tetrahydro-furan-2-ol

japonilure
64726-91-6

japonilure

Conditions
ConditionsYield
With pyridine; chromium(VI) oxide In dichloromethane for 2h; Ambient temperature;30%
(R)-tetrahydro-5-oxo-2-furancarbaldehyde
70606-00-7

(R)-tetrahydro-5-oxo-2-furancarbaldehyde

nonyl(triphenyl)phosphonium bromide

nonyl(triphenyl)phosphonium bromide

japonilure
64726-91-6

japonilure

Conditions
ConditionsYield
With sodium methylsulfinylmethanide 1.) THF, 0 deg C, 1 h, 2a.) DMF, -40 deg C, 2 h, 2b.) RT, overnight; Yield given. Multistep reaction;
(S)-5-<(Z)-dec-1-enyl>dihydrofuran-2(3H)-one
64726-93-8

(S)-5-<(Z)-dec-1-enyl>dihydrofuran-2(3H)-one

japonilure
64726-91-6

japonilure

Conditions
ConditionsYield
With potassium hydroxide; triphenylphosphine; diethylazodicarboxylate 1.) MeOH, 60 deg C, 3 h, 2.) THF, 20 deg C, 13 h; Yield given. Multistep reaction;
With potassium hydroxide; triphenylphosphine; diethylazodicarboxylate 1.) MeOH, 60 deg C, 3h, 2.) benzene, RT, 13h; Yield given. Multistep reaction;
(5S)-1-pentadecen-6-yn-5-ol
397300-95-7

(5S)-1-pentadecen-6-yn-5-ol

japonilure
64726-91-6

japonilure

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: ozone / CH2Cl2 / 0.42 h / -78 °C
1.2: PPh3 / CH2Cl2 / 2 h / -78 °C
1.3: 86 percent / N-iodosuccinimide; N-tetrabutylammonium iodide / CH2Cl2 / 0.25 h / 20 °C
2.1: 94 percent / H2; quinoine / Lindlar catalyst / pentane / 4 h / 0 °C
View Scheme
(1R)-1-(3-butenyl)-2-undecynyl 2,2,4,4-tetramethyl-1,3-oxazolidine-3-carboxylate
397300-89-9

(1R)-1-(3-butenyl)-2-undecynyl 2,2,4,4-tetramethyl-1,3-oxazolidine-3-carboxylate

japonilure
64726-91-6

japonilure

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: MeSO3H / methanol / 8 h / Heating
1.2: 89 percent / Ba(OH)2*8H2O / methanol / 2 h / Heating
2.1: ozone / CH2Cl2 / 0.42 h / -78 °C
2.2: PPh3 / CH2Cl2 / 2 h / -78 °C
2.3: 86 percent / N-iodosuccinimide; N-tetrabutylammonium iodide / CH2Cl2 / 0.25 h / 20 °C
3.1: 94 percent / H2; quinoine / Lindlar catalyst / pentane / 4 h / 0 °C
View Scheme
1-decyne
764-93-2

1-decyne

japonilure
64726-91-6

japonilure

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: lithium diisopropylamide / tetrahydrofuran / 0.25 h / -78 °C
1.2: 97 percent / tetrahydrofuran / 18 h / 20 - 25 °C
2.1: 89 percent / hydrogen peroxide; aq. sodium hydroxide / diethyl ether / 2 h / 25 °C
3.1: 69 percent / p-toluenesulfonic acid / CH2Cl2 / 2 h / 100 °C
4.1: 65 percent / hydrogen / palladium on calcium carbonate / pentane / 1 h / 0 °C / 760 Torr
View Scheme
Multi-step reaction with 4 steps
1: 86.2 percent / n-butyllithium / tetrahydrofuran / 15 h / 1.) 3 deg C, 1 h, 2.) -50 deg C to r.t., 15 h
2: 70.1 percent / AlCl3 / CH2Cl2 / 1.) -65 deg C, 2.5 h, then -40 deg C, 1 h, 2.) -30 deg C, 2 h, then -30 deg C to 0 deg C, 15 h
3: Chirald, LiAlH4 / diethyl ether / 1.) -100 deg C, 2 h, 2.) -70 to -65 deg C, 2 h
4: 71.7 percent / H2, quinoline / 5percent Pd/CaCO3 / pentane / 1 h / 0 °C
View Scheme
Multi-step reaction with 8 steps
1: 1.) ethylmagnesium bromide / 1.) THF, r.t., 1 h, 2.) THF, 5 deg C, 2 h
2: 88 percent / aq. NaIO4 / diethyl ether / 2 h / Ambient temperature
3: 94 percent / silver carbonate on celite (Fetizon's reagent) / benzene / 8.5 h / Heating
4: 89 percent / 90percent trifluoroacetic acid / 0.25 h / Ambient temperature
5: 74.6 percent / H2 / Pb poisoned 5percent Pd/CaCO3 (Lindlar catalyst) / ethanol
6: 770 mg / conc. H2SO4 / 0.25 h / Ambient temperature
7: 1.21 g / acetic anhydride, acetic acid / Heating
8: 1.) CuI, LiI, TMSCl, 2.) n-Bu3SnH / 1.) THF, -60 deg C, 10 min, 2.) up to 0 deg C, 30 min
View Scheme
Multi-step reaction with 3 steps
1: Mg / tetrahydrofuran / 1 h / Heating
2: 68 percent / tetrahydrofuran / -65 deg C, 3 h -> room temperature, 20 h
3: 1.) 9-BBN, (+)-α-pinene, 2.) 2-hydroxyethylamine, 3.) NaH, 4.) H2 / 4.) Pd on CaCO3
View Scheme
Multi-step reaction with 3 steps
1: 85 percent / CuBr-(CH3)2S
2: 1.) Alpine-borane, 2.) NaOH/MeOH / 1.) room temp., 7 d, 2.) reflux, 15 min
3: H2 / Pd/CaCO3 poisoned with lead/quinoline
View Scheme
(R)-[1,1-dimethylethyl-4-hydroxy-5-tetradecynoate]
325141-84-2

(R)-[1,1-dimethylethyl-4-hydroxy-5-tetradecynoate]

japonilure
64726-91-6

japonilure

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 69 percent / p-toluenesulfonic acid / CH2Cl2 / 2 h / 100 °C
2: 65 percent / hydrogen / palladium on calcium carbonate / pentane / 1 h / 0 °C / 760 Torr
View Scheme
[2(1'R),4R,5R]-2-[2-[[(1,1-dimethylethyl)oxy]carbonyl]-1-(1-decynyl)propyl]-4,5-dicyclohexyl-1,3,2-dioxaborolane
325141-83-1

[2(1'R),4R,5R]-2-[2-[[(1,1-dimethylethyl)oxy]carbonyl]-1-(1-decynyl)propyl]-4,5-dicyclohexyl-1,3,2-dioxaborolane

japonilure
64726-91-6

japonilure

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 89 percent / hydrogen peroxide; aq. sodium hydroxide / diethyl ether / 2 h / 25 °C
2: 69 percent / p-toluenesulfonic acid / CH2Cl2 / 2 h / 100 °C
3: 65 percent / hydrogen / palladium on calcium carbonate / pentane / 1 h / 0 °C / 760 Torr
View Scheme
(2R,5R)-2-((Z)-Dec-1-enyl)-5-methoxy-tetrahydro-furan
173464-16-9

(2R,5R)-2-((Z)-Dec-1-enyl)-5-methoxy-tetrahydro-furan

japonilure
64726-91-6

japonilure

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 76 percent / aq. HCl / tetrahydrofuran / 3 h / 55 - 60 °C
2: 30 percent / CrO3, pyridine / CH2Cl2 / 2 h / Ambient temperature
View Scheme
Methyl 3,5,6-trideoxy-2-O-methanesulfonyl-α-L-threo-tetradec-5-(Z)-eno-furanoside
173464-14-7

Methyl 3,5,6-trideoxy-2-O-methanesulfonyl-α-L-threo-tetradec-5-(Z)-eno-furanoside

japonilure
64726-91-6

japonilure

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 43 percent / NaBH4 / hexamethylphosphoric acid triamide / 24 h / 100 °C
2: 76 percent / aq. HCl / tetrahydrofuran / 3 h / 55 - 60 °C
3: 30 percent / CrO3, pyridine / CH2Cl2 / 2 h / Ambient temperature
View Scheme
Methyl 3,5,6-trideoxy-L-threo-tetradec-5-(Z)-eno-furanoside

Methyl 3,5,6-trideoxy-L-threo-tetradec-5-(Z)-eno-furanoside

japonilure
64726-91-6

japonilure

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: 51 percent / Et3N / CH2Cl2 / 2 h / Ambient temperature
2: 43 percent / NaBH4 / hexamethylphosphoric acid triamide / 24 h / 100 °C
3: 76 percent / aq. HCl / tetrahydrofuran / 3 h / 55 - 60 °C
4: 30 percent / CrO3, pyridine / CH2Cl2 / 2 h / Ambient temperature
View Scheme
1-decynyltrimethylsilane
54559-17-0

1-decynyltrimethylsilane

japonilure
64726-91-6

japonilure

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 70.1 percent / AlCl3 / CH2Cl2 / 1.) -65 deg C, 2.5 h, then -40 deg C, 1 h, 2.) -30 deg C, 2 h, then -30 deg C to 0 deg C, 15 h
2: Chirald, LiAlH4 / diethyl ether / 1.) -100 deg C, 2 h, 2.) -70 to -65 deg C, 2 h
3: 71.7 percent / H2, quinoline / 5percent Pd/CaCO3 / pentane / 1 h / 0 °C
View Scheme
Methyl 4-Oxo-5-tetradecynoate
77889-02-2

Methyl 4-Oxo-5-tetradecynoate

japonilure
64726-91-6

japonilure

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: Chirald, LiAlH4 / diethyl ether / 1.) -100 deg C, 2 h, 2.) -70 to -65 deg C, 2 h
2: 71.7 percent / H2, quinoline / 5percent Pd/CaCO3 / pentane / 1 h / 0 °C
View Scheme
Multi-step reaction with 2 steps
1: 1.) Alpine-borane, 2.) NaOH/MeOH / 1.) room temp., 7 d, 2.) reflux, 15 min
2: H2 / Pd/CaCO3 poisoned with lead/quinoline
View Scheme
Multi-step reaction with 3 steps
1: 1.) lithium aluminum hydride, R-2,2'-dihydroxy-1,1'-binaphthyl, CH3OH / 1.) THF, room temperature, 2.) -100 deg C, 1 h and -78 deg C, 2 h
2: p-toluenesulfonic acid / benzene / 1 h / Heating
3: 90 percent / Lindlar cat.
View Scheme
methyl (RS)-4-hydroxy-5-tetradecynoate
78685-94-6

methyl (RS)-4-hydroxy-5-tetradecynoate

japonilure
64726-91-6

japonilure

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: NaOH / methanol / 0.25 h / Heating
2: 0.5 h / 120 °C / 0.2 Torr
3: 71.7 percent / H2, quinoline / 5percent Pd/CaCO3 / pentane / 1 h / 0 °C
View Scheme
Multi-step reaction with 3 steps
1: 83 percent / pyridine
2: 41 percent / 24 h / 25 °C / lipase OF, phosphate buffer, pH 7
3: 91 percent / H2, quinoline / Lindlar catalyst / pentane / 5 h / 0 °C
View Scheme
Multi-step reaction with 3 steps
1: 41 percent / diisopropyl ether / 48 h / Ambient temperature; lipase PS
2: 83 percent / 23 h / 25 °C / lipase OF, phosphate buffer, pH 7
3: 91 percent / H2, quinoline / Lindlar catalyst / pentane / 5 h / 0 °C
View Scheme
Multi-step reaction with 3 steps
1: 43 percent / diisopropyl ether / 30 h / Ambient temperature; lipase PS
2: 81 percent / 5percent KOH, methanol / 0.25 h / Heating
3: 91 percent / H2, quinoline / Lindlar catalyst / pentane / 5 h / 0 °C
View Scheme
Multi-step reaction with 5 steps
1: 88 percent / pyridine
2: 43 percent / H2O / 16 h / 25 °C / palatase A, phosphate buffer, pH 7
3: 80 percent / diisopropyl ether / 10 h / Ambient temperature; lipase PS
4: 81 percent / 5percent KOH, methanol / 0.25 h / Heating
5: 91 percent / H2, quinoline / Lindlar catalyst / pentane / 5 h / 0 °C
View Scheme
(4R,5S,6R)-5,6-dihydroxy-tetradecan-4-olide
111192-37-1

(4R,5S,6R)-5,6-dihydroxy-tetradecan-4-olide

japonilure
64726-91-6

japonilure

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 90 percent / p-TsOH / CH2Cl2 / 0.5 h / Ambient temperature
2: 2) aq. sodium acetate / 1) acetic anhydride, reflux, 140 deg C, 1.5 h; 2) H2O, 4 h, 10 deg C
View Scheme
(R)-4-hydroxy-5-tetradecynoic acid
88939-18-8

(R)-4-hydroxy-5-tetradecynoic acid

japonilure
64726-91-6

japonilure

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 0.5 h / 120 °C / 0.2 Torr
2: 71.7 percent / H2, quinoline / 5percent Pd/CaCO3 / pentane / 1 h / 0 °C
View Scheme
(4R,5S,6R)-ethyl-4-benzyloxy-5,6-(isopropylidenedioxy)-2,7-tetradecadienate

(4R,5S,6R)-ethyl-4-benzyloxy-5,6-(isopropylidenedioxy)-2,7-tetradecadienate

japonilure
64726-91-6

japonilure

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 1) H2; 2) 90 percent aq. CF3COOH / 1) Pd-black / 1) 5 percent CH3COOH/MeOH, RT, 4-6 h; 2) H2O, RT, 3 h
2: 90 percent / p-TsOH / CH2Cl2 / 0.5 h / Ambient temperature
3: 2) aq. sodium acetate / 1) acetic anhydride, reflux, 140 deg C, 1.5 h; 2) H2O, 4 h, 10 deg C
View Scheme
(2S,3R,4S,5Z)-2,3-dihydroxy-5-tetradecen-4-olide
147618-20-0

(2S,3R,4S,5Z)-2,3-dihydroxy-5-tetradecen-4-olide

japonilure
64726-91-6

japonilure

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 770 mg / conc. H2SO4 / 0.25 h / Ambient temperature
2: 1.21 g / acetic anhydride, acetic acid / Heating
3: 1.) CuI, LiI, TMSCl, 2.) n-Bu3SnH / 1.) THF, -60 deg C, 10 min, 2.) up to 0 deg C, 30 min
View Scheme
japonilure
64726-91-6

japonilure

(4R,5Z)-5-tetradecene-1,4-diol
105676-77-5

(4R,5Z)-5-tetradecene-1,4-diol

Conditions
ConditionsYield
With lithium aluminium tetrahydride In tetrahydrofuran for 1h; Ambient temperature;
japonilure
64726-91-6

japonilure

(Z)-(R)-1-(tert-Butyl-dimethyl-silanyloxy)-tetradec-5-en-4-ol

(Z)-(R)-1-(tert-Butyl-dimethyl-silanyloxy)-tetradec-5-en-4-ol

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: LiAlH4 / tetrahydrofuran / 1 h / Ambient temperature
2: 4-dimethylaminopyridine, triethylamine / CH2Cl2 / 2 h
View Scheme
japonilure
64726-91-6

japonilure

(4R,5Z)-1-t-butyldimethylsilyloxy-5-tetradecene-1-yl benzoate

(4R,5Z)-1-t-butyldimethylsilyloxy-5-tetradecene-1-yl benzoate

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: LiAlH4 / tetrahydrofuran / 1 h / Ambient temperature
2: 4-dimethylaminopyridine, triethylamine / CH2Cl2 / 2 h
3: pyridine / 1 h / Ambient temperature
View Scheme
japonilure
64726-91-6

japonilure

(4R,5Z)-5-tetradecene-1,4-diyl dibenzoate

(4R,5Z)-5-tetradecene-1,4-diyl dibenzoate

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: LiAlH4 / tetrahydrofuran / 1 h / Ambient temperature
2: pyridine / 1 h / Ambient temperature
View Scheme

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