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Enke Pharma-tech Co.,Ltd. (Cangzhou, China )

Cangzhou Enke Pharma Tech Co.,ltd. is located in Cangzhou City, Hebei province ,where is a famous petroleum chemical industry city in China. Enke Pharma a high-tech enterprise ,and we are dedicated to developing and manufacturing new ap

2-Bromo-6-fluoroaniline

Cas:65896-11-9

Min.Order:1 Kilogram

FOB Price: $5.0 / 10.0

Type:Manufacturers

inquiry

Hangzhou JINLAN Pharm-Drugs Technology Co., Ltd

We can provide GMP validation service that complies with SFDA, FDA, WHO and EU EMPA.Excellent registration team could help us easlily to register our products in different countries.If you and your customer are interested in some products or need C

2-BROMO-6-FLUOROANILINE manufacturer with low price

Cas:65896-11-9

Min.Order:1 Gram

Negotiable

Type:Manufacturers

inquiry

Henan Allgreen Chemical Co.,Ltd

The company has a professional R & D team, mature technology, very competitive prices and stable high quality products for customers to order high quality and low price product efforts! Appearance:Clear yellow to brown Liquid Storage:Sealed, dr

4-Cyanophenylhydrazine hydrochloride

Cas:65896-11-9

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply 2-Bromo-6-fluoroaniline

Cas:65896-11-9

Min.Order:1

Negotiable

Type:Other

inquiry

Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem’s R&D center offer custom synthesis according to the contract research and development services for the fine c

2-Bromo-6-fluoroaniline

Cas:65896-11-9

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

2-Bromo-6-fluoroaniline

Cas:65896-11-9

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Pharmaceutical Grade CAS 65896-11-9 with competitive price

Cas:65896-11-9

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Henan Sinotech Import&Export Corporation

Product Name: 2-BROMO-6-FLUOROANILINE Synonyms: 2-Bromo-6-fluoroaniline 99%;2-BROMO-6-FLUOROANILINE;2-Bromo-6-fluoroaniline, 98+%;2-Bromo-6-fluoroaniline,95%;2-broMo-6-fluorobenzenaMine;2-BroMo-6-fluoro-phe

2-Bromo-6-fluoroaniline CAS: 65896-11-9

Cas:65896-11-9

Min.Order:5 Kilogram

FOB Price: $1.0 / 2.0

Type:Other

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

Benzenamine,2-bromo-6-fluoro- 65896-11-9

Cas:65896-11-9

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Qingdao Beluga Import and Export Co., LTD

2-BROMO-6-FLUOROANILINE CAS:65896-11-9 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic i

2-BROMO-6-FLUOROANILINE CAS:65896-11-9

Cas:65896-11-9

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Benzenamine,2-bromo-6-fluoro-

Cas:65896-11-9

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

CAS NO.:65896-11-9

Cas:65896-11-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

2-Bromo-6-fluoroaniline

Cas:65896-11-9

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

2-BROMO-6-FLUOROANILINE

Cas:65896-11-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

2-Bromo-6-fluoroaniline

Cas:65896-11-9

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

Shanghai Massive Chemical Technology Co., Ltd.

Massive Chemical is certified with ISO9001 and ISO14001 manufacturer for this product. We will offer all documents as requirement for the materials which includes, Certificate of Analysis, Material Safety Data Sheet, and Method of Analysis and

2-BROMO-6-FLUOROANILINE

Cas:65896-11-9

Min.Order:1 Gram

FOB Price: $1.0

Type:Lab/Research institutions

inquiry

Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O

2-BROMO-6-FLUOROANILINE

Cas:65896-11-9

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Huarong Pharm Co., Ltd.

Hangzhou Huarong Pharm Co., Ltd. established since 2009 , has been always focusing on supplying products and services to our clients in the field of small molecule drug. Huarong Pharm has built platforms for the research, development and manufac

2-BROMO-6-FLUOROANILINE

Cas:65896-11-9

Min.Order:1 Gram

FOB Price: $1.0 / 2.0

Type:Trading Company

inquiry

Zibo Dorne chemical technology co. LTD

Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,

2-BroMo-6-fluoro-phenylaMine

Cas:65896-11-9

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Xiamen Jenny Chemical Technology Co., Ltd.

GMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,

2-Bromo-6-fluoroaniline

Cas:65896-11-9

Min.Order:1 Milligram

Negotiable

Type:Trading Company

inquiry

Shanghai Minstar Chemical Co., Ltd

Product Name: 2-BROMO-6-FLUOROANILINE Synonyms: 2-BROMO-6-FLUOROANILINE;2-Bromo-6-fluoroaniline, 98+%;2-Bromo-6-fluoroaniline 99%;Letermovir Intermediate 1;2-Bromo-6-fluoroaniline,95%;2-BroMo-6-fluoro-phenylaMine;2-broMo-6-fluorobenzenaMine;2-B

2-BROMO-6-FLUOROANILINE

Cas:65896-11-9

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

65896-11-9 2-Bromo-6-fluoroaniline /High quality/Best price/In stock

Cas:65896-11-9

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

inquiry

TAIZHOU ZHENYU BIOTECHNOLOGY CO., LTD

Zhenyu biotech exported this product to many countries and regions at best price. if you are looking for the material's manufacturer or supplier in china, zhenyu biotech is your best choice. pls contact with us freely for getting detailed

2-BROMO-6-FLUOROANILINE

Cas:65896-11-9

Min.Order:1 Kilogram

FOB Price: $2.0

Type:Lab/Research institutions

inquiry

Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

2-BROMO-6-FLUOROANILINE

Cas:65896-11-9

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

65896-11-9 2-Bromo-6-fluoroaniline /High quality/Best price/In stock

Cas:65896-11-9

Min.Order:1 Metric Ton

FOB Price: $1.5

Type:Trading Company

inquiry

Suzhou Health Chemicals Co., Ltd.

High quality,stable supply chain.Appearance:white/off-white or light yellow Storage:Store in cool and dry place, keep away from strong light and heat. Package:aluminum bottle,glass bottle,PTFE bottle,cardboard drum Application:This product can be use

2-bromo-6-fluoroaniline

Cas:65896-11-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Golden Pharma Co., Limited

GOLDEN PHARMA CO.,LIMITED.is a professional pharmaceutical company,our team have more than 20years expereince in pharmaceutical production and sales. we are a professional technical enterprise specializing in the R & D, production,QA regulation

2-Bromo-6-fluoroaniline

Cas:65896-11-9

Min.Order:1 Kilogram

Negotiable

Type:Other

inquiry

Bluecrystal chem-union

We are a Union of chemistry in China, consists of chemists,engineers, laboratories,factories in China. We organize surplus capacity of R&D and production as well as custom synthesis for chemical products and chemical business project. We are supp

2-Bromo-6-fluoroaniline

Cas:65896-11-9

Min.Order:1 Metric Ton

FOB Price: $1.0

Type:Trading Company

inquiry

Changzhou Anchor Biological Technology Co., Ltd.

Our company is engaged in customizing the benzene ring and pyridine derivative organic intermediates, and the quantity is flexible according to customer's needs. It mainly provides high-quality intermediates for domestic and foreign pharmaceutical an

2-Bromo-6-fluoroaniline Manufacturer/High quality/Best price/In stock CAS NO.65896-11-9

Cas:65896-11-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Win-Win chemical Co.Ltd

Stock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

2-Bromo-6-Fluoroaniline cas no. 65896-11-9 98%

Cas:65896-11-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

2-bromo-6-fluorobenzoic acid
2252-37-1

2-bromo-6-fluorobenzoic acid

2-bromo-6-fluoroaniline
65896-11-9

2-bromo-6-fluoroaniline

Conditions
ConditionsYield
Stage #1: 2-bromo-6-fluorobenzoic acid With sulfuric acid at 60℃; for 1.5h;
Stage #2: With sodium azide at 20℃; for 42h; Schmidt rearrangement;
Stage #3: With ammonium hydroxide at 0℃;
86%
2-Fluoroaniline
348-54-9

2-Fluoroaniline

A

4-bromo-2-fluoroaniline
367-24-8

4-bromo-2-fluoroaniline

B

2,4-dibromo-6-fluorophenylamine
141474-37-5

2,4-dibromo-6-fluorophenylamine

C

2-bromo-6-fluoroaniline
65896-11-9

2-bromo-6-fluoroaniline

Conditions
ConditionsYield
Stage #1: 2-Fluoroaniline With n-butyllithium In diethyl ether; hexane at -78℃; for 1h;
Stage #2: With poly[4-(dibutyliodostannyl)butyl]styrene In diethyl ether; hexane at 20℃; for 18h;
Stage #3: With bromine In diethyl ether; hexane; dichloromethane at -78 - 20℃; for 2h;
A 70%
B n/a
C n/a
2-Fluoroaniline
348-54-9

2-Fluoroaniline

A

4-bromo-2-fluoroaniline
367-24-8

4-bromo-2-fluoroaniline

B

2-bromo-6-fluoroaniline
65896-11-9

2-bromo-6-fluoroaniline

Conditions
ConditionsYield
With sodium perborate; ammonium heptamolybdate; potassium bromide In acetic acid at 20℃; for 1h; Bromination;
2-Fluoroaniline
348-54-9

2-Fluoroaniline

2-bromo-6-fluoroaniline
65896-11-9

2-bromo-6-fluoroaniline

Conditions
ConditionsYield
With hydrogen bromide; dimethyl sulfoxide In ethyl acetate at 60℃; for 12h;
acetic anhydride
108-24-7

acetic anhydride

2-bromo-6-fluoroaniline
65896-11-9

2-bromo-6-fluoroaniline

N-(2-bromo-6-fluorophenyl)acetamide

N-(2-bromo-6-fluorophenyl)acetamide

Conditions
ConditionsYield
In dichloromethane Inert atmosphere; Reflux;100%
2-Methoxyphenylboronic acid
5720-06-9

2-Methoxyphenylboronic acid

2-bromo-6-fluoroaniline
65896-11-9

2-bromo-6-fluoroaniline

3-fluoro-2'-methoxy-[1,1'-biphenyl]-2-amine
1338379-58-0

3-fluoro-2'-methoxy-[1,1'-biphenyl]-2-amine

Conditions
ConditionsYield
With tetrakis(triphenylphosphine) palladium(0); sodium carbonate In ethanol; water; toluene at 80℃; for 108h; Inert atmosphere;98%
With palladium diacetate; 2-dicyclohexylphosphino-2',6'-dimethylbiphenyl In toluene at 100℃; for 3h;62%
acrylic acid methyl ester
292638-85-8

acrylic acid methyl ester

2-bromo-6-fluoroaniline
65896-11-9

2-bromo-6-fluoroaniline

C10H10FNO2

C10H10FNO2

Conditions
ConditionsYield
With N-Methyldicyclohexylamine; chloro[(tri-tert-butylphosphine)-2-(2-aminobiphenyl)] palladium(II) In Isopropyl acetate at 80℃; for 5h; Inert atmosphere;97%
2-bromo-6-fluoroaniline
65896-11-9

2-bromo-6-fluoroaniline

2‑bromo‑6‑fluoronitrobenzene
886762-70-5

2‑bromo‑6‑fluoronitrobenzene

Conditions
ConditionsYield
With 3-chloro-benzenecarboperoxoic acid In 1,2-dichloro-ethane at 70℃; for 2h;88%
Stage #1: 2-bromo-6-fluoroaniline With 3-chloro-benzenecarboperoxoic acid In dichloromethane for 0.5h; Reflux;
Stage #2: With dihydrogen peroxide; nitric acid; acetic acid at 20 - 90℃; for 0.5h;
Stage #1: 2-bromo-6-fluoroaniline With 3-chloro-benzenecarboperoxoic acid In dichloromethane for 0.5h; Reflux;
Stage #2: With dihydrogen peroxide; nitric acid In acetic acid at 20 - 90℃; for 0.5h;
2-methoxy-5-trifluoromethylphenyl isocyanate
16588-75-3

2-methoxy-5-trifluoromethylphenyl isocyanate

2-bromo-6-fluoroaniline
65896-11-9

2-bromo-6-fluoroaniline

3-(2-bromo-6-fluorophenyl)-1-[2-methoxy-5-(trifluoromethyl)phenyl]urea
917389-23-2

3-(2-bromo-6-fluorophenyl)-1-[2-methoxy-5-(trifluoromethyl)phenyl]urea

Conditions
ConditionsYield
In acetonitrile at 35 - 88℃; for 38 - 45h; Product distribution / selectivity;87.5%
Glutaraldehyde
111-30-8

Glutaraldehyde

2-bromo-6-fluoroaniline
65896-11-9

2-bromo-6-fluoroaniline

C11H13BrFN

C11H13BrFN

Conditions
ConditionsYield
Stage #1: Glutaraldehyde; 2-bromo-6-fluoroaniline With sodium tris(acetoxy)borohydride In tetrahydrofuran at 0℃; for 1h;
Stage #2: With sodium triacetoxy borohydride In tetrahydrofuran at 0 - 20℃; for 3h;
85%
carbon monoxide
201230-82-2

carbon monoxide

aniline
62-53-3

aniline

2-bromo-6-fluoroaniline
65896-11-9

2-bromo-6-fluoroaniline

trimethyl orthoformate
149-73-5

trimethyl orthoformate

8-Ffuoro-3-phenylquinazolin-4(3H)-one
1593583-16-4

8-Ffuoro-3-phenylquinazolin-4(3H)-one

Conditions
ConditionsYield
With palladium diacetate; N-ethyl-N,N-diisopropylamine; catacxium A In 1,4-dioxane at 100℃; under 7500.75 Torr; for 16h; Inert atmosphere; Autoclave;84%
carbon monoxide
201230-82-2

carbon monoxide

acetic anhydride
108-24-7

acetic anhydride

2-bromo-6-fluoroaniline
65896-11-9

2-bromo-6-fluoroaniline

8-fluoro-2-methyl-4H-benzo[d][1,3]oxazin-4-one
1044749-59-8

8-fluoro-2-methyl-4H-benzo[d][1,3]oxazin-4-one

Conditions
ConditionsYield
With potassium tetrachloropalladate(II); N-ethyl-N,N-diisopropylamine; catacxium A In toluene at 100℃; under 1500.15 Torr; for 16h; Autoclave;83%
4-methoxyphenylboronic acid
5720-07-0

4-methoxyphenylboronic acid

2-bromo-6-fluoroaniline
65896-11-9

2-bromo-6-fluoroaniline

C13H12FNO

C13H12FNO

Conditions
ConditionsYield
With tetrakis(triphenylphosphine) palladium(0); sodium carbonate In 1,4-dioxane; water at 80℃; Inert atmosphere;81%
2-bromo-6-fluoroaniline
65896-11-9

2-bromo-6-fluoroaniline

methyl iodide
74-88-4

methyl iodide

C8H9BrFN

C8H9BrFN

Conditions
ConditionsYield
Stage #1: 2-bromo-6-fluoroaniline With potassium carbonate In N,N-dimethyl-formamide at 20℃; for 0.166667h; Inert atmosphere;
Stage #2: methyl iodide In N,N-dimethyl-formamide at 20℃; for 18h; Inert atmosphere;
80%
2-bromo-6-fluoroaniline
65896-11-9

2-bromo-6-fluoroaniline

isopropyl zinc bromide
77047-87-1

isopropyl zinc bromide

2-fluoro-6-isopropylaniline
126476-48-0

2-fluoro-6-isopropylaniline

Conditions
ConditionsYield
With palladium diacetate In tetrahydrofuran at 20℃; for 3h; Inert atmosphere; Sealed tube;77%
pivaloyl chloride
3282-30-2

pivaloyl chloride

2-bromo-6-fluoroaniline
65896-11-9

2-bromo-6-fluoroaniline

N-(2-bromo-6-fluorophenyl)pivalamide
865626-99-9

N-(2-bromo-6-fluorophenyl)pivalamide

Conditions
ConditionsYield
With pyridine at 20℃; for 3h;76%
With pyridine In methanol at 20℃; for 3h;76%
With triethylamine In dichloromethane at 0 - 20℃;
N-methylaniline
100-61-8

N-methylaniline

2-bromo-6-fluoroaniline
65896-11-9

2-bromo-6-fluoroaniline

C13H11BrFN3

C13H11BrFN3

Conditions
ConditionsYield
Stage #1: 2-bromo-6-fluoroaniline With hydrogenchloride In acetonitrile at 20℃;
Stage #2: With sodium nitrite In water; acetonitrile at 0℃;
Stage #3: N-methylaniline at 0 - 20℃; pH=< 6 - < 8;
76%
Stage #1: 2-bromo-6-fluoroaniline With hydrogenchloride In acetonitrile at 0℃; for 0.25h;
Stage #2: With sodium nitrite In water; acetonitrile at 0 - 5℃; for 0.5h;
Stage #3: N-methylaniline With sodium hydrogencarbonate In acetonitrile pH=6 - 8;
tert-butylisonitrile
119072-55-8, 7188-38-7

tert-butylisonitrile

carbon dioxide
124-38-9

carbon dioxide

2-bromo-6-fluoroaniline
65896-11-9

2-bromo-6-fluoroaniline

3-(tert-butyl)-8-fluoroquinazoline-2,4(1H,3H)-dione

3-(tert-butyl)-8-fluoroquinazoline-2,4(1H,3H)-dione

Conditions
ConditionsYield
With palladium diacetate; triphenylphosphine; cesium fluoride In dimethyl sulfoxide at 90℃; under 15001.5 Torr; for 12h; Reagent/catalyst; Schlenk technique; Autoclave;74%
acrylic acid methyl ester
292638-85-8

acrylic acid methyl ester

2-bromo-6-fluoroaniline
65896-11-9

2-bromo-6-fluoroaniline

methyl (2E)-3-(2-amino-3-fluorophenyl)acrylate
690664-20-1

methyl (2E)-3-(2-amino-3-fluorophenyl)acrylate

Conditions
ConditionsYield
With triethylamine; palladium diacetate; tris-(o-tolyl)phosphine In acetonitrile for 48h; Heck Reaction; Heating / reflux;68%
With triethylamine; palladium diacetate; tris-(o-tolyl)phosphine In acetonitrile for 48h;68%
With triethylamine; palladium diacetate; tris-(o-tolyl)phosphine for 48h; Heck Reaction;68%
With triethylamine; palladium diacetate; tris-(o-tolyl)phosphine In acetonitrile for 48h; Heck coupling; Heating / reflux;68%
With N-Methyldicyclohexylamine; chloro[(tri-tert-butylphosphine)-2-(2-aminobiphenyl)]palladium (II) In Isopropyl acetate at 80℃; for 5h; Heck Reaction; Inert atmosphere; Large scale;16.2 kg
trifluoroacetic acid
76-05-1

trifluoroacetic acid

2-bromo-6-fluoroaniline
65896-11-9

2-bromo-6-fluoroaniline

N-(2-bromo-6-hydroxyphenyl)-2,2,2-trifluoroacetamide

N-(2-bromo-6-hydroxyphenyl)-2,2,2-trifluoroacetamide

Conditions
ConditionsYield
With Oxone In 1,4-dioxane at 90℃; Schlenk technique; Inert atmosphere; chemoselective reaction;68%
ethyl N-(2-cyano-4-nitrophenyl)formimidate
22363-16-2

ethyl N-(2-cyano-4-nitrophenyl)formimidate

2-bromo-6-fluoroaniline
65896-11-9

2-bromo-6-fluoroaniline

N-(2-bromo-6-fluorophenyl)-6-nitroquinazolin-4-amine
1474030-52-8

N-(2-bromo-6-fluorophenyl)-6-nitroquinazolin-4-amine

Conditions
ConditionsYield
With acetic acid for 1h; Dimroth Rearrangement; Reflux;67%
C18H17NO3
884048-29-7

C18H17NO3

2-bromo-6-fluoroaniline
65896-11-9

2-bromo-6-fluoroaniline

C24H21FN2O3
884034-53-1

C24H21FN2O3

Conditions
ConditionsYield
With isopropylamine; bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide In N,N-dimethyl-formamide at 90℃; for 0.5h;62%
p-toluenesulfonyl chloride
98-59-9

p-toluenesulfonyl chloride

2-bromo-6-fluoroaniline
65896-11-9

2-bromo-6-fluoroaniline

N-(2-bromo-6-fluorophenyl)-4-methylbenzenesulfonamide

N-(2-bromo-6-fluorophenyl)-4-methylbenzenesulfonamide

Conditions
ConditionsYield
With pyridine In tetrahydrofuran at 40℃;61%
2-bromo-6-fluoroaniline
65896-11-9

2-bromo-6-fluoroaniline

1-bromo-2-iodo-3-methoxybenzene
450412-22-3

1-bromo-2-iodo-3-methoxybenzene

2-bromo-N-(2-bromo-6-methoxyphenyl)-6-fluoroaniline

2-bromo-N-(2-bromo-6-methoxyphenyl)-6-fluoroaniline

Conditions
ConditionsYield
With tris(dibenzylideneacetone)dipalladium(0) chloroform complex; 2,2'-bis(diphenylphosphino)biphenyl; sodium t-butanolate In toluene for 94h; Inert atmosphere; Reflux;61%
4-methyl-3-cyclohexen-1-one
5259-65-4

4-methyl-3-cyclohexen-1-one

2-bromo-6-fluoroaniline
65896-11-9

2-bromo-6-fluoroaniline

8-fluoro-4a-methyl-4,4a,9,9a-tetrahydro-1H-carbazol-2(3H)-one

8-fluoro-4a-methyl-4,4a,9,9a-tetrahydro-1H-carbazol-2(3H)-one

Conditions
ConditionsYield
With potassium carbonate; tris(dibenzylideneacetone)dipalladium (0); 1,1'-bis(diisopropylphosphino)ferrocene In toluene at 110℃; for 8h;60%
(2,3-difluorophenyl)boronic acid
121219-16-7

(2,3-difluorophenyl)boronic acid

2-bromo-6-fluoroaniline
65896-11-9

2-bromo-6-fluoroaniline

2',3,3'-trifluoro-[1,1'-biphenyl]-2-amine

2',3,3'-trifluoro-[1,1'-biphenyl]-2-amine

Conditions
ConditionsYield
With tetrakis(triphenylphosphine) palladium(0); potassium carbonate In methanol; toluene for 15h; Inert atmosphere; Reflux;60%
4,4-dimethylpent-1-en-3-ol
60041-31-8, 61348-36-5, 24580-44-7

4,4-dimethylpent-1-en-3-ol

2-bromo-6-fluoroaniline
65896-11-9

2-bromo-6-fluoroaniline

2-(tert-butyl)-8-fluoroquinoline
1286756-88-4

2-(tert-butyl)-8-fluoroquinoline

Conditions
ConditionsYield
Stage #1: 4,4-dimethylpent-1-en-3-ol; 2-bromo-6-fluoroaniline With bis(η3-allyl-μ-chloropalladium(II)); N-Methyldicyclohexylamine; di-tert-butyl (2'-methyl-[1,1'-biphenyl]-2-yl)phosphine In acetonitrile at 90℃; for 1h; Improved Larock synthesis; Inert atmosphere;
Stage #2: With di-isopropyl azodicarboxylate; acetic acid In acetonitrile at 90℃; for 0.25h; Improved Larock synthesis; Inert atmosphere;
59%
4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane
25015-63-8

4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane

2-bromo-6-fluoroaniline
65896-11-9

2-bromo-6-fluoroaniline

2-fluoro-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline

2-fluoro-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline

Conditions
ConditionsYield
With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; triethylamine In 1,4-dioxane at 100℃; for 12h; Inert atmosphere;58%
bis(trichloromethyl) carbonate
32315-10-9

bis(trichloromethyl) carbonate

(S)-(-)-1-methyl-1,2,3,4-tetrahydroisoquinoline hydrochloride
64982-62-3

(S)-(-)-1-methyl-1,2,3,4-tetrahydroisoquinoline hydrochloride

2-bromo-6-fluoroaniline
65896-11-9

2-bromo-6-fluoroaniline

(1S)-N-(2-bromo-6-fluorophenyl)-1-methyl-3,4-dihydroisoquinoline-2(1H)-carboxamide

(1S)-N-(2-bromo-6-fluorophenyl)-1-methyl-3,4-dihydroisoquinoline-2(1H)-carboxamide

Conditions
ConditionsYield
Stage #1: bis(trichloromethyl) carbonate; 2-bromo-6-fluoroaniline In tetrahydrofuran at 0 - 20℃; for 1.5h;
Stage #2: (S)-(-)-1-methyl-1,2,3,4-tetrahydroisoquinoline hydrochloride With triethylamine In tetrahydrofuran at 20 - 60℃;
52%
ethyl N-phenylformimidate
6780-49-0

ethyl N-phenylformimidate

2-bromo-6-fluoroaniline
65896-11-9

2-bromo-6-fluoroaniline

N-(6-fluoro-2-bromophenyl)-N’-phenylformamidine

N-(6-fluoro-2-bromophenyl)-N’-phenylformamidine

Conditions
ConditionsYield
In neat (no solvent) at 50℃;49%
bis(pinacol)diborane
73183-34-3

bis(pinacol)diborane

2-bromo-6-fluoroaniline
65896-11-9

2-bromo-6-fluoroaniline

2-fluoro-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline

2-fluoro-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline

Conditions
ConditionsYield
With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium acetate In N,N-dimethyl-formamide at 80℃; for 12h;49%
2-bromo-6-fluoroaniline
65896-11-9

2-bromo-6-fluoroaniline

4-Bromophenyl isothiocyanate
1985-12-2

4-Bromophenyl isothiocyanate

N-(4-bromophenyl)-4-fluorobenzothiazol-2-ylamine
1431300-97-8

N-(4-bromophenyl)-4-fluorobenzothiazol-2-ylamine

Conditions
ConditionsYield
Stage #1: 2-bromo-6-fluoroaniline; 4-Bromophenyl isothiocyanate In dimethyl sulfoxide at 18 - 25℃; for 0.5h; Inert atmosphere;
Stage #2: With copper(l) iodide In dimethyl sulfoxide at 120℃; Inert atmosphere;
45.2%

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