As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch
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inquiryWelcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our
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inquiryProduct Description Product website: http://www.finerchem.com Product Name 7-Hydroxyquinolinone CAS No. 70500-72-0
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inquiryhigh quality Appearance:White or off-white Solid Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea Port:shanghai
The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi
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inquiryCangzhou Enke Pharma Tech Co.,ltd. is located in Cangzhou City, Hebei province ,where is a famous petroleum chemical industry city in China. Enke Pharma a high-tech enterprise ,and we are dedicated to developing and manufacturing new ap
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inquiryOur advantages: 1. All inquiries will be replied within 12 hours. 2. Dedication to quality, supply & service. 3. Strictly on selecting raw materials. 4. Reasonable & competitive price, fast lead time. 5. Sample is available for your eva
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inquiryWhy is SINOWAY: 1) Specialized in pharmaceutical and healthcare industrial for 34 years. 2) ISO 9001:2015 & SGS audited supplier . 3) Accept various payment terms : T.T 30-60 days. 4) We have warehouse in USA with quickly shipment . 5) We c
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inquiryOur company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O
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inquiryWITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et
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inquiryAdvantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the R&
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inquiry1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; Appearance:white crystalline powder Storage:Store in sealed containers
Cas:70500-72-0
Min.Order:100 Gram
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inquiry7-Hydroxyquinolinone [70500-72-0] HANGZHOU THINK CHEMICAL CO., LTD. (THINKCHEM) is an integrative corporation of trade, research and contract manufacture. With about ten years of business experiences on the marketing & distribut
Cas:70500-72-0
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inquiryAbout Product Details Items Specifications Test Results Appearance White to white crystalline powde
Cas:70500-72-0
Min.Order:100 Kilogram
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inquiryOur company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At prese
Cas:70500-72-0
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inquiry7-Hydroxyquinolinone CAS:70500-72-0 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic inte
Cas:70500-72-0
Min.Order:1 Gram
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inquiryHello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai
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inquiry1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France etc. 3) OEM/ODM Available; 4) Reasonable & Compet
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inquiryProduct Name: 7-Hydroxyquinolinone Synonyms: Aripiprazole Impurity 16;7- hydroxy-2-quinolone;2,7-DIHYDROXYQUINOLINE;7-HYDROXY-2-QUINOLINONE;7-HYDROXY-1H-QUINOLIN-2-ONE;7-hydroxy-2(1H)-Quino;7-hydroxy-2-(1h)-quinolinone;7-HYDROXYQUINOLINE-2(1H)-O
Cas:70500-72-0
Min.Order:100 Gram
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Type:Lab/Research institutions
inquiryProduct Detail Minimum Order Qty. 10 Gram
Cas:70500-72-0
Min.Order:10 Gram
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Type:Trading Company
inquiryBest quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia
Appearance:white or light yellow crystalline powder Storage:Store in a cool,dry place and keep away from direct strong light Package:As customer request Application:Used for research and industrial manufacture. Transportation:By Se
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inquiryOur Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We
Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det
Cas:70500-72-0
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inquiryJ&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia
Our Services 1. New Molecules R&D 2. Own test center HPLC NMR GC LC-MS 3. API and Intermediates from China reputed manufacturers 4. Documents support COA MOA MSDS DMF open part Our advantages 1. Government awarded company. Top 100 enter
A substitute for perfluorooctanoic acid, mainly used as a surfactant, dispersant, additive, etc Appearance:White solid or Colorless liquid Purity:99.3 % We will ship the goods in a timely manner as required We can provide relevant documents acc
Cas:70500-72-0
Min.Order:4 Kilogram
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Type:Lab/Research institutions
inquiryChemlyte Solutions believe that customers and suppliers deserve much more than what traditional distributors can offer. To grow in today s fast-paced and increasingly competitive market it is essential to be able to quickly adapt to market forces eff
Cas:70500-72-0
Min.Order:100 Gram
Negotiable
Type:Other
inquiry7-hydroxy-3,4-dihydro-2-(1H)-quinolinone
7-hydroxy-1H-quinolin-2-one
Conditions | Yield |
---|---|
With palladium 10% on activated carbon; water; oxygen; acetic acid at 110 - 116℃; for 18h; Reagent/catalyst; Temperature; | 94.2% |
With palladium 10% on activated carbon In decalin at 180℃; for 8h; | 90.9% |
With 2,3-dicyano-5,6-dichloro-p-benzoquinone In tetrahydrofuran at 66℃; for 4h; Catalytic behavior; Concentration; Solvent; Temperature; | 89% |
2-oxo-1,2-dihydroquinolin-7-yl-acetate
7-hydroxy-1H-quinolin-2-one
Conditions | Yield |
---|---|
With sodium hydroxide In water for 1.5h; | 90% |
7-hydroxy-1H-quinolin-2-one
Conditions | Yield |
---|---|
Stage #1: C18H20BNO6 With aluminum (III) chloride; tris(pentafluorophenyl)borate In 5,5-dimethyl-1,3-cyclohexadiene at 0 - 70℃; for 2h; Stage #2: With dihydrogen peroxide; acetic acid In 5,5-dimethyl-1,3-cyclohexadiene at 0 - 20℃; for 2h; | 82.2% |
7-hydroxy-1H-quinolin-2-one
Conditions | Yield |
---|---|
Stage #1: C17H18BNO5 With aluminum (III) chloride; tris(pentafluorophenyl)borate In toluene at 0 - 90℃; for 2h; Stage #2: With dihydrogen peroxide; acetic acid In toluene at 0 - 20℃; for 2h; | 81.3% |
(2E)-N-(3-methoxyphenyl)-3-phenylacrylamide
7-hydroxy-1H-quinolin-2-one
Conditions | Yield |
---|---|
With aluminium trichloride In chlorobenzene at 120℃; for 2h; | 70% |
With aluminium trichloride In chlorobenzene | 70% |
With aluminum (III) chloride In chlorobenzene at 0℃; for 8h; Reflux; | 67% |
7-hydroxy-2H-chromen-2-one
7-hydroxy-1H-quinolin-2-one
Conditions | Yield |
---|---|
With acetic acid In acetic acid for 3h; Substitution; Heating; | 55% |
N-(3-methoxyphenyl)cinnamamide
7-hydroxy-1H-quinolin-2-one
Conditions | Yield |
---|---|
With aluminum (III) chloride In chlorobenzene at 0 - 120℃; | 53% |
With aluminum (III) chloride at 120 - 180℃; for 2.08333h; | 43% |
With aluminum (III) chloride at 120 - 180℃; for 2h; |
m-Anisidine
7-hydroxy-1H-quinolin-2-one
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: 95 percent 2: 70 percent / AlCl3 / chlorobenzene View Scheme | |
Multi-step reaction with 2 steps 1: potassium carbonate / water; acetone / 20 °C / Cooling with ice 2: aluminum (III) chloride / chlorobenzene / 0 - 120 °C View Scheme | |
Multi-step reaction with 2 steps 1: pyridine / dichloromethane / 1 h / 5 - 20 °C 2: aluminum (III) chloride / 2.08 h / 120 - 180 °C View Scheme | |
Multi-step reaction with 2 steps 1: potassium carbonate / acetone; water / 0.5 h 2: aluminum (III) chloride / chlorobenzene / 120 °C / Cooling with ice View Scheme | |
Multi-step reaction with 2 steps 1: potassium carbonate / acetone; water / 0.5 h / 0 °C 2: aluminum (III) chloride / chlorobenzene / Reflux View Scheme |
7-hydroxyquinoline 1-oxide
7-hydroxy-1H-quinolin-2-one
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: 24 percent / 2 h / Heating 2: 90 percent / 1.0 N NaOH / H2O / 1.5 h View Scheme |
m-Anisidine
7-hydroxy-1H-quinolin-2-one
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: 95 percent / aq. K2CO3 / acetone / 0.5 h / 0 °C 2: 70 percent / AlCl3 / chlorobenzene / 2 h / 120 °C View Scheme |
m-Hydroxyaniline
7-hydroxy-1H-quinolin-2-one
Conditions | Yield |
---|---|
With pyridine; AlCl3 In dichloromethane; ethyl acetate | |
Multi-step reaction with 3 steps 1.1: sodium hydrogencarbonate / dichloromethane / 0.5 h / 20 °C / Inert atmosphere 1.2: 2 h / 20 °C / Inert atmosphere 2.1: aluminum (III) chloride / N,N-dimethyl acetamide / 4 h / 70 - 140 °C 3.1: 2,3-dicyano-5,6-dichloro-p-benzoquinone / tetrahydrofuran / 2 h / 20 - 50 °C / Inert atmosphere 3.2: 1 h / 20 °C / Inert atmosphere View Scheme | |
Multi-step reaction with 3 steps 1: sodium hydrogencarbonate / ethyl acetate / 20 - 30 °C 2: aluminum (III) chloride / N,N-dimethyl acetamide / 130 - 140 °C 3: palladium 10% on activated carbon; water; acetic acid; oxygen / 18 h / 110 - 116 °C View Scheme |
3-chloro-N-(3-hydroxyphenyl)propanamide
7-hydroxy-1H-quinolin-2-one
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1.1: aluminum (III) chloride / N,N-dimethyl acetamide / 4 h / 70 - 140 °C 2.1: 2,3-dicyano-5,6-dichloro-p-benzoquinone / tetrahydrofuran / 2 h / 20 - 50 °C / Inert atmosphere 2.2: 1 h / 20 °C / Inert atmosphere View Scheme | |
Multi-step reaction with 2 steps 1: aluminum (III) chloride / N,N-dimethyl acetamide / 130 - 140 °C 2: palladium 10% on activated carbon; water; acetic acid; oxygen / 18 h / 110 - 116 °C View Scheme |
3,4-dimethoxy-trans-cinnamic acid
7-hydroxy-1H-quinolin-2-one
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1.1: thionyl chloride / toluene / 4 h / 70 °C 2.1: triethylamine / tetrahydrofuran / 2 h / -5 - 20 °C 3.1: tris(pentafluorophenyl)borate; aluminum (III) chloride / toluene / 2 h / 0 - 90 °C 3.2: 2 h / 0 - 20 °C View Scheme |
(E)-3,4-dimethoxycinnamic chloride
7-hydroxy-1H-quinolin-2-one
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1.1: triethylamine / tetrahydrofuran / 2 h / -5 - 20 °C 2.1: tris(pentafluorophenyl)borate; aluminum (III) chloride / toluene / 2 h / 0 - 90 °C 2.2: 2 h / 0 - 20 °C View Scheme |
(E)-3,4,5-trimethoxy-cinnamic acid
7-hydroxy-1H-quinolin-2-one
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1.1: thionyl chloride / toluene / 4 h / 70 °C 2.1: pyridine / tetrahydrofuran / 2 h / -5 - 20 °C 3.1: tris(pentafluorophenyl)borate; aluminum (III) chloride / 5,5-dimethyl-1,3-cyclohexadiene / 2 h / 0 - 70 °C 3.2: 2 h / 0 - 20 °C View Scheme |
(E)-3-(3,4,5-trimethoxyphenyl)acryloyl chloride
7-hydroxy-1H-quinolin-2-one
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1.1: pyridine / tetrahydrofuran / 2 h / -5 - 20 °C 2.1: tris(pentafluorophenyl)borate; aluminum (III) chloride / 5,5-dimethyl-1,3-cyclohexadiene / 2 h / 0 - 70 °C 2.2: 2 h / 0 - 20 °C View Scheme |
Conditions | Yield |
---|---|
Stage #1: m-Anisidine; Cinnamoyl chloride In dichloromethane for 4h; Reflux; Stage #2: With aluminum (III) chloride In chlorobenzene for 8h; Reflux; |
7-hydroxy-1H-quinolin-2-one
2-chloroquinoline-7-ol
Conditions | Yield |
---|---|
With trichlorophosphate In N,N-dimethyl-formamide at 70 - 75℃; Reagent/catalyst; | 94% |
With thionyl chloride In N,N-dimethyl-formamide at 0 - 70℃; for 1h; | 80.9% |
4-chlorobutyl bromide
7-hydroxy-1H-quinolin-2-one
Conditions | Yield |
---|---|
With potassium carbonate In N,N-dimethyl-formamide at 40 - 50℃; for 5h; | 93.7% |
With triethylamine In ethanol at 60 - 80℃; for 2h; Concentration; Solvent; Temperature; Reagent/catalyst; | 92.2% |
With sodium hydroxide In ethanol for 5h; Reflux; | 88% |
acetic anhydride
7-hydroxy-1H-quinolin-2-one
2-oxo-1,2-dihydroquinolin-7-yl-acetate
Conditions | Yield |
---|---|
With indium(III) triflate at 0 - 30℃; for 1h; | 90% |
7-hydroxy-1H-quinolin-2-one
tert-butyl 4-bromobutylcarbamate
Conditions | Yield |
---|---|
With potassium carbonate In water; N,N-dimethyl-formamide at 45 - 55℃; | 87.4% |
1,4-dibromo-butane
7-hydroxy-1H-quinolin-2-one
7–(4-bromobutoxy)quinolin-2(1H)-one
Conditions | Yield |
---|---|
With potassium carbonate In acetone at 20℃; for 3h; Reflux; | 86.5% |
With potassium carbonate In water; N,N-dimethyl-formamide at 30 - 40℃; for 4h; | 82% |
With potassium carbonate In acetone for 4h; Reflux; | 78% |
7-hydroxy-1H-quinolin-2-one
Diphenylphosphine oxide
Conditions | Yield |
---|---|
With eosin; dibenzoyl peroxide In water; dimethyl sulfoxide at 20℃; for 24h; Inert atmosphere; Irradiation; regioselective reaction; | 86% |
3,4-difluoronitrobenzene
7-hydroxy-1H-quinolin-2-one
Conditions | Yield |
---|---|
With potassium carbonate In N,N-dimethyl-formamide at 20℃; | 86% |
1-bromo-4-aminobutane
7-hydroxy-1H-quinolin-2-one
Conditions | Yield |
---|---|
Stage #1: 4-bromo-1-aminobutane With potassium carbonate In N,N-dimethyl-formamide at 20℃; for 0.5h; Stage #2: 7-hydroxy-1H-quinolin-2-one With sodium iodide In N,N-dimethyl-formamide at 100℃; for 0.666667h; Temperature; | 84.3% |
7-hydroxy-1H-quinolin-2-one
Conditions | Yield |
---|---|
With potassium carbonate; potassium iodide In N,N-dimethyl-formamide at 80 - 90℃; | 84.1% |
7-hydroxy-1H-quinolin-2-one
Conditions | Yield |
---|---|
With potassium carbonate; potassium iodide In N,N-dimethyl-formamide at 80 - 90℃; for 20h; | 83% |
Conditions | Yield |
---|---|
With potassium carbonate In N,N-dimethyl-formamide at 130 - 135℃; Reagent/catalyst; Temperature; | 82% |
4-Bromo-1-butanol
7-hydroxy-1H-quinolin-2-one
Conditions | Yield |
---|---|
With potassium carbonate In N,N-dimethyl-formamide for 24h; Reflux; | 81% |
With potassium carbonate In water; N,N-dimethyl-formamide at 40 - 50℃; | 81.4% |
4-chlorobutanal dimethyl acetal
7-hydroxy-1H-quinolin-2-one
Conditions | Yield |
---|---|
Stage #1: 7-hydroxy-1H-quinolin-2-one With potassium carbonate In N,N-dimethyl-formamide at 25 - 35℃; for 0.5h; Stage #2: 4-chlorobutanal dimethyl acetal In N,N-dimethyl-formamide at 70 - 75℃; for 10h; | 80% |
With tetrabutylammomium bromide; potassium carbonate In dimethyl sulfoxide at 20 - 70℃; for 20h; |
4-Chloro-1-butanol
7-hydroxy-1H-quinolin-2-one
Conditions | Yield |
---|---|
Stage #1: 7-hydroxy-1H-quinolin-2-one With potassium carbonate In N,N-dimethyl-formamide at 25 - 35℃; for 0.5h; Stage #2: 4-Chloro-1-butanol In N,N-dimethyl-formamide at 70 - 75℃; | 80% |
7-hydroxy-1H-quinolin-2-one
1,3-dibromo-propane
7–(3-bromopropoxy)quinolin-2(1H)-one
Conditions | Yield |
---|---|
With potassium carbonate In acetone for 4h; Reflux; | 79% |
With potassium carbonate In ethanol Reflux; | 55% |
With potassium carbonate In acetonitrile at 50℃; for 20h; |
7-hydroxy-1H-quinolin-2-one
Conditions | Yield |
---|---|
With phosphorus tribromide In N,N-dimethyl-formamide at 70 - 75℃; | 79% |
Methyl 4-bromobutyrate
7-hydroxy-1H-quinolin-2-one
4-(2-Oxo-1,2-dihydro-quinolin-7-yloxy)-butyric acid methyl ester
Conditions | Yield |
---|---|
With 1,8-diazabicyclo[5.4.0]undec-7-ene In isopropyl alcohol for 4h; Heating; | 78% |
4-chloro-1,1-diethoxybutane
7-hydroxy-1H-quinolin-2-one
Conditions | Yield |
---|---|
With tetrabutylammomium bromide; sodium carbonate In dimethyl sulfoxide at 100 - 110℃; for 3h; Reagent/catalyst; Solvent; Temperature; Large scale; | 78% |
2,4-dichlorothieno[3,2-d]pyrimidine
7-hydroxy-1H-quinolin-2-one
Conditions | Yield |
---|---|
With potassium carbonate In water; acetonitrile at 70℃; | 78% |
With potassium carbonate In water; acetonitrile Reflux; | 78% |
7-hydroxy-1H-quinolin-2-one
Conditions | Yield |
---|---|
With N,N-dimethyl acetamide; potassium carbonate; 4-methyl-2-pentanone at 116 - 118℃; for 20h; Reagent/catalyst; | 77.9% |
7-hydroxy-1H-quinolin-2-one
ethylene dibromide
Conditions | Yield |
---|---|
With potassium carbonate In acetone for 4h; Reflux; | 77% |
With potassium hydroxide In methanol at 65℃; for 4h; Inert atmosphere; | 16.2% |
1,5-dibromo-pentane
7-hydroxy-1H-quinolin-2-one
Conditions | Yield |
---|---|
With potassium carbonate In acetone for 4h; Reflux; | 76% |
With potassium carbonate In acetonitrile at 50℃; for 20h; |
7-hydroxy-1H-quinolin-2-one
2-bromo-4'-fluoroacetophenone
7-<2-(4-fluorophenyl)-2-oxoethoxy>quinolin-2(1H)-one
Conditions | Yield |
---|---|
With potassium carbonate In N,N-dimethyl-formamide for 24.5h; Ambient temperature; | 75% |
1-ethyl-2-methylquinolinium iodide
7-hydroxy-1H-quinolin-2-one
Conditions | Yield |
---|---|
With piperidine In ethanol Condensation; Heating; | 75% |
7-hydroxy-1H-quinolin-2-one
allyl bromide
7-(prop-2-en-1-yloxy)-1,2-dihydroquinolin-2-one
Conditions | Yield |
---|---|
With potassium carbonate In acetone at 60℃; for 16h; | 74% |
With potassium carbonate In acetone at 60℃; for 16h; | 74% |
1 ,6-dibromohexane
7-hydroxy-1H-quinolin-2-one
Conditions | Yield |
---|---|
With potassium carbonate In acetone for 4h; Reflux; | 74% |
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