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Shanghai SE Pharm Co., Ltd

1. made in GMP plant, commerially 2. Normal Stock: 500kgs 3. Audit accepted. Related documents are available to offer and audited by many clients, such as Lupin, MSN, Dr reddy etc 4. Chromatographic Purity (HPLC): not less than 99

2-(5-Chloro-2-phenoxyphenyl)acetic acid

Cas:70958-20-2

Min.Order:0 Metric Ton

Negotiable

Type:Manufacturers

inquiry

Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem’s R&D center offer custom synthesis according to the contract research and development services for the fine c

2-(5-Chloro-2-phenoxyphenyl)acetic acid

Cas:70958-20-2

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

5-Chloro-2-phenoxybenzeneacetic acid

Cas:70958-20-2

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Henan Tianfu Chemical Co., Ltd.

TIANFUCHEM--70958-20-2--High purity 5-Chloro-2-phenoxyphenylacetic acid factory price Our company was built in 2009 with an ISO certificate.In the past 10 years, we have grown up as a famous fine chemicals supplier in China And we had esta

TIANFUCHEM--70958-20-2--High purity 5-Chloro-2-phenoxyphenylacetic acid factory price

Cas:70958-20-2

Min.Order:1 Metric Ton

FOB Price: $2000.0

Type:Lab/Research institutions

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Best priceCAS 70958-20-2 with high quality products

Cas:70958-20-2

Min.Order:10 Gram

FOB Price: $146.0 / 176.0

Type:Trading Company

inquiry

Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

TIANFUCHEM--70958-20-2--High purity 5-Chloro-2-phenoxyphenylacetic acid factory price

Cas:70958-20-2

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

5-Chloro-2-phenoxyphenylacetic acid 70958-20-2

Cas:70958-20-2

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Qingdao Beluga Import and Export Co., LTD

5-Chloro-2-phenoxyphenylacetic acid CAS:70958-20-2 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high qual

5-Chloro-2-phenoxyphenylacetic acid CAS:70958-20-2

Cas:70958-20-2

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

5-Chloro-2-phenoxyphenylacetic acid

Cas:70958-20-2

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

5-Chloro-2-phenoxyphenylacetic acid

Cas:70958-20-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Afine Chemicals Limited

Our Services 1. New Molecules R&D 2. Own test center HPLC NMR GC LC-MS 3. API and Intermediates from China reputed manufacturers 4. Documents support COA MOA MSDS DMF open part Our advantages 1. Government awarded company. Top 100 enter

2-(5-Chloro-2-phenoxyphenyl)acetic acid

Cas:70958-20-2

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

Our Advantage Rich Experience Our products are sold all over Europe,North&South America, Sino-East, Asia and pacific area as well as Africa,we establish long term. Quality service Company cooperates with research institutes. We strictly con

70958-20-2 5-Chloro-2-phenoxyphenylacetic acid

Cas:70958-20-2

Min.Order:1 Kilogram

FOB Price: $15.0 / 50.0

Type:Trading Company

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

2-(5-Chloro-2-phenoxyphenyl)acetic acid

Cas:70958-20-2

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

5-Chloro-2-phenoxyphenylacetic acid

Cas:70958-20-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

2-(5-Chloro-2-phenoxyphenyl)acetic acid

Cas:70958-20-2

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

SHANGHAI SYSTEAM BIOCHEM CO., LTD

We are one of a few suppliers that can offer custom synthesis service of this product We are specialized in custom synthesis, chemical/pharmaceutical/ pesticides outsourcing and contract research. We are committed to prov

2-(5-Chloro-2-phenoxyphenyl)acetic acid

Cas:70958-20-2

Min.Order:100 Gram

FOB Price: $100.0 / 2000.0

Type:Lab/Research institutions

inquiry

HANGZHOU YUNUO CHEMICAL CO.,LTD

Superior quality, moderate price & quick delivery. Appearance:White crystalline powder Storage:Room temperature, tight from air Package:10g/bag,or as your request Application:For medicine , pesticide intermediates Transportation: as your re

2-(5-Chloro-2-phenoxyphenyl)acetic acid

Cas:70958-20-2

Min.Order:1 Gram

Negotiable

Type:Trading Company

inquiry

Hangzhou Huarong Pharm Co., Ltd.

Huarong Industrial Group Limited established since 2006 , has been actively developing specialty products for Finished Dosages, APIs, Intermediates, and Fine chemicals markets in North America, Europe, Korea, Japan, Mid-East and all over the World.

5-Chloro-2-phenoxyphenylacetic acid

Cas:70958-20-2

Min.Order:1 Gram

FOB Price: $1.0 / 2.0

Type:Trading Company

inquiry

Zibo Dorne chemical technology co. LTD

Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,

5-Chloro-2-phenoxyphenylacetic acid

Cas:70958-20-2

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Maytime Bio-Tech Co.,Ltd.

we are manufacturer of Asenapine intermediates with good price and service. Appearance:white to off-white powder Storage:keep from moisture,sealed in container container,room temperature. Application:Asenapine intermediate Port:shanghai seaport or

2-(5-Chloro-2-phenoxyphenyl)acetic acid

Cas:70958-20-2

Min.Order:1 Kilogram

Negotiable

Type:Other

inquiry

EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

TIANFUCHEM--70958-20-2--High purity 5-Chloro-2-phenoxyphenylacetic acid factory price

Cas:70958-20-2

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

inquiry

Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

2-(5-Chloro-2-phenoxyphenyl)acetic acid

Cas:70958-20-2

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

TIANFUCHEM--70958-20-2--High purity 5-Chloro-2-phenoxyphenylacetic acid factory price

Cas:70958-20-2

Min.Order:1 Metric Ton

FOB Price: $1.5

Type:Trading Company

inquiry

Hunan chemfish Pharmaceutical co.,Ltd

Appearance:95%+ Package:R&D,Pilot run Transportation:per client require Port:Express ,Air, Sea

2-(5-Chloro-2-phenoxyphenyl)acetic acid

Cas:70958-20-2

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Suzhou Health Chemicals Co., Ltd.

High quality,stable supply chain.Appearance:white/off-white or light yellow Storage:Store in cool and dry place, keep away from strong light and heat. Package:aluminum bottle,glass bottle,PTFE bottle,cardboard drum Application:This product can be use

2-(5-chloro-2-phenoxyphenyl)acetic Acid

Cas:70958-20-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Bluecrystal chem-union

We are a Union of chemistry in China, consists of chemists,engineers, laboratories,factories in China. We organize surplus capacity of R&D and production as well as custom synthesis for chemical products and chemical business project. We are supp

TIANFUCHEM--70958-20-2--High purity 5-Chloro-2-phenoxyphenylacetic acid factory price

Cas:70958-20-2

Min.Order:1 Metric Ton

FOB Price: $1.0

Type:Trading Company

inquiry

Win-Win chemical Co.Ltd

Stock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

2-(5-Chloro-2-phenoxyphenyl)acetic acid cas no. 70958-20-2 98%

Cas:70958-20-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Kono Chem Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou

(5-chloro-2-phenoxyphenyl)acetic acid

Cas:70958-20-2

Min.Order:0

Negotiable

Type:Other

inquiry

Hangzhou Dingyan Chem Co., Ltd

R & D enterprises have their own stock in stockAppearance:To be subject to the object Package:Customized Application:pharmaceutical intermediates Transportation:Air Port:Shanghai;Guangzhou

2-(5-Chloro-2-phenoxyphenyl)acetic acid

Cas:70958-20-2

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

GIHI CHEMICALS CO.,LIMITED

high purity,in stock Package:25kg/drum,or as per customers'demand Application:API,Pharmaceutical intermediates Transportation:air,sea,courier

2-(5-Chloro-2-phenoxyphenyl)acetic acid

Cas:70958-20-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

5-chloro-2-phenoxyacetophenone
70958-18-8

5-chloro-2-phenoxyacetophenone

5-chloro-2-phenoxyphenylacetic acid
70958-20-2

5-chloro-2-phenoxyphenylacetic acid

Conditions
ConditionsYield
Stage #1: 5-chloro-2-phenoxyacetophenone With morpholine; sulfur at 110℃; for 12h;
Stage #2: With hydrogenchloride; acetic acid In water for 8h; Reflux;
67.1%
With morpholine; hydrogenchloride; sulfur; acetic acid 1.) reflux, 12 h, 2.) reflux, 8 h; Yield given. Multistep reaction;
Multi-step reaction with 2 steps
1: sulfur / 24 h / Heating
2: KOH / methanol / 72 h / Heating
View Scheme
4-[2-(5-chloro-2-phenoxyphenyl)-1-thioxoethyl]morpholine
70958-19-9

4-[2-(5-chloro-2-phenoxyphenyl)-1-thioxoethyl]morpholine

5-chloro-2-phenoxyphenylacetic acid
70958-20-2

5-chloro-2-phenoxyphenylacetic acid

Conditions
ConditionsYield
With potassium hydroxide In methanol for 72h; Heating;
2,5-dichloroacetophenone
2476-37-1

2,5-dichloroacetophenone

5-chloro-2-phenoxyphenylacetic acid
70958-20-2

5-chloro-2-phenoxyphenylacetic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 63 percent / K2CO3, Cu / 10 h / Heating
2: 1.) morpholine, sulfur, 2.) glacial acetic acid, conc. aq. HCl / 1.) reflux, 12 h, 2.) reflux, 8 h
View Scheme
Multi-step reaction with 3 steps
1: phenol, copper / 24 h / 120 - 125 °C
2: sulfur / 24 h / Heating
3: KOH / methanol / 72 h / Heating
View Scheme
Multi-step reaction with 2 steps
1.1: potassium carbonate / copper / 10 h / 130 °C
2.1: morpholine; sulfur / 12 h / 110 °C
2.2: 8 h / Reflux
View Scheme
phenol
108-95-2

phenol

(+-)-1-<1-chloro-cyclohexyl>-cyclohexanone-(2)

(+-)-1-<1-chloro-cyclohexyl>-cyclohexanone-(2)

5-chloro-2-phenoxyphenylacetic acid
70958-20-2

5-chloro-2-phenoxyphenylacetic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 63 percent / K2CO3, Cu / 10 h / Heating
2: 1.) morpholine, sulfur, 2.) glacial acetic acid, conc. aq. HCl / 1.) reflux, 12 h, 2.) reflux, 8 h
View Scheme
sodium phenoxide
139-02-6

sodium phenoxide

2-methoxy-m-phenylene disodium

2-methoxy-m-phenylene disodium

5-chloro-2-phenoxyphenylacetic acid
70958-20-2

5-chloro-2-phenoxyphenylacetic acid

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: phenol, copper / 24 h / 120 - 125 °C
2: sulfur / 24 h / Heating
3: KOH / methanol / 72 h / Heating
View Scheme
phenol
108-95-2

phenol

5-chloro-2-phenoxyphenylacetic acid
70958-20-2

5-chloro-2-phenoxyphenylacetic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: potassium carbonate / copper / 10 h / 130 °C
2.1: morpholine; sulfur / 12 h / 110 °C
2.2: 8 h / Reflux
View Scheme
methanol
67-56-1

methanol

5-chloro-2-phenoxyphenylacetic acid
70958-20-2

5-chloro-2-phenoxyphenylacetic acid

(5-chloro-2-phenoxy-phenyl)-acetic acid methyl ester
1141493-78-8

(5-chloro-2-phenoxy-phenyl)-acetic acid methyl ester

Conditions
ConditionsYield
With sulfuric acid at 50℃; for 2h;98%
5-chloro-2-phenoxyphenylacetic acid
70958-20-2

5-chloro-2-phenoxyphenylacetic acid

2-chloro-10,11-dihydrodibenzoxepin-10-one
55595-54-5

2-chloro-10,11-dihydrodibenzoxepin-10-one

Conditions
ConditionsYield
With PPA at 100 - 105℃;61%
With sodium hydroxide; PPA
5-chloro-2-phenoxyphenylacetic acid
70958-20-2

5-chloro-2-phenoxyphenylacetic acid

(5-Chloro-2-phenoxy-phenyl)-acetyl chloride

(5-Chloro-2-phenoxy-phenyl)-acetyl chloride

Conditions
ConditionsYield
With thionyl chloride In toluene Heating;
With thionyl chloride In toluene
5-chloro-2-phenoxyphenylacetic acid
70958-20-2

5-chloro-2-phenoxyphenylacetic acid

1-[2-chloro-dibenz[b,f]oxepin-10-yl]-4-methyl-piperazine
57389-06-7

1-[2-chloro-dibenz[b,f]oxepin-10-yl]-4-methyl-piperazine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 61 percent / polyphosphoric acid / 100 - 105 °C
2: 60 percent / TiCl4 / benzene / 4 h / Heating
View Scheme
5-chloro-2-phenoxyphenylacetic acid
70958-20-2

5-chloro-2-phenoxyphenylacetic acid

8-chloro-dibenz[b,f]oxepin-10-carboxylic acid methyl ester
912356-02-6

8-chloro-dibenz[b,f]oxepin-10-carboxylic acid methyl ester

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: sulfuric acid / 2 h / 50 °C
2: sodium t-butanolate / tert-butyl methyl ether / 2 h / 5 - 20 °C
3: pyrophosphoric acid / water / 2 h / 0 - 60 °C
View Scheme
5-chloro-2-phenoxyphenylacetic acid
70958-20-2

5-chloro-2-phenoxyphenylacetic acid

(E and Z)-2-(5-chloro-2-phenoxy-phenyl)-3-hydroxy-acrylic acid methyl ester
912356-01-5

(E and Z)-2-(5-chloro-2-phenoxy-phenyl)-3-hydroxy-acrylic acid methyl ester

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: sulfuric acid / 2 h / 50 °C
2: sodium t-butanolate / tert-butyl methyl ether / 2 h / 5 - 20 °C
View Scheme
5-chloro-2-phenoxyphenylacetic acid
70958-20-2

5-chloro-2-phenoxyphenylacetic acid

trans-5-Chloro-2-methyl-2,3,3a,12b-tetrahydro-1H-dibenz<2,3:6,7>oxepino<4,5-c>pyrrolidine maleate
85650-56-2

trans-5-Chloro-2-methyl-2,3,3a,12b-tetrahydro-1H-dibenz<2,3:6,7>oxepino<4,5-c>pyrrolidine maleate

Conditions
ConditionsYield
Multi-step reaction with 8 steps
1.1: sulfuric acid / 2 h / 50 °C
2.1: sodium t-butanolate / tert-butyl methyl ether / 2 h / 5 - 20 °C
3.1: pyrophosphoric acid / water / 2 h / 0 - 60 °C
4.1: 1,8-diazabicyclo[5.4.0]undec-7-ene / 20 - 35 °C
5.1: hydrogen / Ni-Raney / tetrahydrofuran / 48 h / 20 °C / 2585.81 - 3102.97 Torr
6.1: ethyl acetate / 96 h / 25 °C
7.1: boron trifluoride diethyl etherate; triethylsilane / 24 h / 105 °C
8.1: sodium hydroxide / dichloromethane; water / pH > 10
8.2: 2 h / 60 °C
View Scheme
5-chloro-2-phenoxyphenylacetic acid
70958-20-2

5-chloro-2-phenoxyphenylacetic acid

trans-8-chloro-11-nitromethyl-10,11-dihydro-dibenzo[b,f]oxepine-10-carboxylic acid methyl ester

trans-8-chloro-11-nitromethyl-10,11-dihydro-dibenzo[b,f]oxepine-10-carboxylic acid methyl ester

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: sulfuric acid / 2 h / 50 °C
2: sodium t-butanolate / tert-butyl methyl ether / 2 h / 5 - 20 °C
3: pyrophosphoric acid / water / 2 h / 0 - 60 °C
4: 1,8-diazabicyclo[5.4.0]undec-7-ene / 20 - 35 °C
View Scheme
5-chloro-2-phenoxyphenylacetic acid
70958-20-2

5-chloro-2-phenoxyphenylacetic acid

11-aminomethyl-8-chloro-10,11-dihydro-dibenzo[b,f]oxepine-10-carboxylic acid methyl ester

11-aminomethyl-8-chloro-10,11-dihydro-dibenzo[b,f]oxepine-10-carboxylic acid methyl ester

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: sulfuric acid / 2 h / 50 °C
2: sodium t-butanolate / tert-butyl methyl ether / 2 h / 5 - 20 °C
3: pyrophosphoric acid / water / 2 h / 0 - 60 °C
4: 1,8-diazabicyclo[5.4.0]undec-7-ene / 20 - 35 °C
5: hydrogen / Ni-Raney / tetrahydrofuran / 48 h / 20 °C / 2585.81 - 3102.97 Torr
View Scheme
5-chloro-2-phenoxyphenylacetic acid
70958-20-2

5-chloro-2-phenoxyphenylacetic acid

trans-11-chloro-2,3,3a,12b-tetrahydro-1H-dibenz[2,3:6,7]oxepino[4,5-c]pyrrol-1-one

trans-11-chloro-2,3,3a,12b-tetrahydro-1H-dibenz[2,3:6,7]oxepino[4,5-c]pyrrol-1-one

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1: sulfuric acid / 2 h / 50 °C
2: sodium t-butanolate / tert-butyl methyl ether / 2 h / 5 - 20 °C
3: pyrophosphoric acid / water / 2 h / 0 - 60 °C
4: 1,8-diazabicyclo[5.4.0]undec-7-ene / 20 - 35 °C
5: hydrogen / Ni-Raney / tetrahydrofuran / 48 h / 20 °C / 2585.81 - 3102.97 Torr
6: ethyl acetate / 96 h / 25 °C
View Scheme
5-chloro-2-phenoxyphenylacetic acid
70958-20-2

5-chloro-2-phenoxyphenylacetic acid

trans-5-chloro-2,3,3a,12b-tetrahydro-1H-dibenzo[2,3:6,7]oxepino[4,5-c]pyrrole hydrochloride

trans-5-chloro-2,3,3a,12b-tetrahydro-1H-dibenzo[2,3:6,7]oxepino[4,5-c]pyrrole hydrochloride

Conditions
ConditionsYield
Multi-step reaction with 7 steps
1: sulfuric acid / 2 h / 50 °C
2: sodium t-butanolate / tert-butyl methyl ether / 2 h / 5 - 20 °C
3: pyrophosphoric acid / water / 2 h / 0 - 60 °C
4: 1,8-diazabicyclo[5.4.0]undec-7-ene / 20 - 35 °C
5: hydrogen / Ni-Raney / tetrahydrofuran / 48 h / 20 °C / 2585.81 - 3102.97 Torr
6: ethyl acetate / 96 h / 25 °C
7: boron trifluoride diethyl etherate; triethylsilane / 24 h / 105 °C
View Scheme
5-chloro-2-phenoxyphenylacetic acid
70958-20-2

5-chloro-2-phenoxyphenylacetic acid

trans-5-chloro-2,3,3a,12b-tetrahydro-1H-dibenz<2,3:6,7>oxepino<4,5-c>pyrrole
128915-56-0, 136085-14-8, 136085-16-0, 136085-18-2

trans-5-chloro-2,3,3a,12b-tetrahydro-1H-dibenz<2,3:6,7>oxepino<4,5-c>pyrrole

Conditions
ConditionsYield
Multi-step reaction with 7 steps
1.1: sulfuric acid / 2 h / 50 °C
2.1: sodium t-butanolate / tert-butyl methyl ether / 2 h / 5 - 20 °C
3.1: pyrophosphoric acid / water / 2 h / 0 - 60 °C
4.1: 1,8-diazabicyclo[5.4.0]undec-7-ene / 20 - 35 °C
5.1: hydrogen / Ni-Raney / tetrahydrofuran / 48 h / 20 °C / 2585.81 - 3102.97 Torr
6.1: ethyl acetate / 96 h / 25 °C
7.1: lithium aluminium tetrahydride; aluminum (III) chloride / tetrahydrofuran / 0 - 20 °C
7.2: 0.33 h / 2 °C
View Scheme
5-chloro-2-phenoxyphenylacetic acid
70958-20-2

5-chloro-2-phenoxyphenylacetic acid

C18H18ClNO4

C18H18ClNO4

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: thionyl chloride / toluene
2: triethylamine / N,N-dimethyl-formamide
View Scheme
5-chloro-2-phenoxyphenylacetic acid
70958-20-2

5-chloro-2-phenoxyphenylacetic acid

3-(5-chloro-2-phenoxyphenyl)-1-methylpyrrolidine-2,4-dione
1162120-35-5

3-(5-chloro-2-phenoxyphenyl)-1-methylpyrrolidine-2,4-dione

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: thionyl chloride / toluene
2: triethylamine / N,N-dimethyl-formamide
3: potassium tert-butylate / toluene
View Scheme
5-chloro-2-phenoxyphenylacetic acid
70958-20-2

5-chloro-2-phenoxyphenylacetic acid

11-chloro-2-methyl-2,3-dihydro-1H-dibenzo[2,3:6,7]oxepino[4,5-c]pyrrol-1-one
1012884-46-6

11-chloro-2-methyl-2,3-dihydro-1H-dibenzo[2,3:6,7]oxepino[4,5-c]pyrrol-1-one

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: thionyl chloride / toluene
2: triethylamine / N,N-dimethyl-formamide
3: potassium tert-butylate / toluene
4: phosphoric acid; phosphorus pentoxide / toluene
View Scheme
5-chloro-2-phenoxyphenylacetic acid
70958-20-2

5-chloro-2-phenoxyphenylacetic acid

trans-11-chloro-2,3,3a,12b-tetrahydro-2-methyl-1H-dibenz[2,3:6,7]oxepino[4,5-c]pyrrol-1-one

trans-11-chloro-2,3,3a,12b-tetrahydro-2-methyl-1H-dibenz[2,3:6,7]oxepino[4,5-c]pyrrol-1-one

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: thionyl chloride / toluene
2: triethylamine / N,N-dimethyl-formamide
3: potassium tert-butylate / toluene
4: phosphoric acid; phosphorus pentoxide / toluene
5: magnesium / methanol; toluene; dichloromethane / 5 h / 40 °C / Inert atmosphere; Large scale
View Scheme
5-chloro-2-phenoxyphenylacetic acid
70958-20-2

5-chloro-2-phenoxyphenylacetic acid

cis-11-chloro-2,3,3a,12btetrahydro-2-methyl-1H-dibenz[2,3:6,7]oxepino[4,5-c]pyrrol-1-one

cis-11-chloro-2,3,3a,12btetrahydro-2-methyl-1H-dibenz[2,3:6,7]oxepino[4,5-c]pyrrol-1-one

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: thionyl chloride / toluene
2: triethylamine / N,N-dimethyl-formamide
3: potassium tert-butylate / toluene
4: phosphoric acid; phosphorus pentoxide / toluene
5: magnesium / methanol; toluene; dichloromethane / 5 h / 40 °C / Inert atmosphere; Large scale
View Scheme
5-chloro-2-phenoxyphenylacetic acid
70958-20-2

5-chloro-2-phenoxyphenylacetic acid

trans-8-chloro-10,11-dihydro-11-[(methylamino)methyl]-dibenz[b,f]oxepin-10-carboxylic acid

trans-8-chloro-10,11-dihydro-11-[(methylamino)methyl]-dibenz[b,f]oxepin-10-carboxylic acid

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1: thionyl chloride / toluene
2: triethylamine / N,N-dimethyl-formamide
3: potassium tert-butylate / toluene
4: phosphoric acid; phosphorus pentoxide / toluene
5: magnesium / methanol; toluene; dichloromethane / 5 h / 40 °C / Inert atmosphere; Large scale
6: potassium hydroxide / ethanol / 5 h / 106 °C / Reflux
View Scheme

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