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AstaTech ( Chengdu) BioPharmaceutical Corp.

Chengdu AstaTech Chemical Technology Co., Ltd. is a wholly-owned subsidiary of AstaTech (Chengdu) BioPharmaceutical Co., Ltd. It has overall accountability for AstaTech’s product list and sales and promotion of chemical reagents in China. The company

850222-40-1

Cas:850222-40-1

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Dayang Chem (Hangzhou) Co.,Ltd.

Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities

(S)-3-Dimethylamino-1-(3-methoxyphenyl)-2-methyl-1-propanone Manufacturer/High quality/Best price/In stock

Cas:850222-40-1

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality (2S)-3-(Dimethylamino)-1-(3-Methoxyphenyl)-2-Methyl-1-Propanone supplier in China

Cas:850222-40-1

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

(2S)-3-(Dimethylamino)-1-(3-methoxyphenyl)-2-methyl-1-propanone

Cas:850222-40-1

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Henan Tianfu Chemical Co., Ltd.

Product Name: (S)-3-(dimethylamino)-1-(3-methoxyphenyl)-2-methylpropan-1-one Synonyms: (S)-3-(dimethylamino)-1-(3-methoxyphenyl)-2-methylpropan-1-one;(s)-3-(dimethylamino)-1-(3-methoxyphenyl)-2-methoylpropa

(S)-3-(dimethylamino)-1-(3-methoxyphenyl)-2-methylpropan-1-one

Cas:850222-40-1

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin

(S)-3-(dimethylamino)-1-(3-methoxyphenyl)-2-methylpropan-1-one

Cas:850222-40-1

Min.Order:1 Kilogram

FOB Price: $1.0 / 10.0

Type:Trading Company

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

New production CAS 850222-40-1 with best quality

Cas:850222-40-1

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Hubei Langyou International Trading Co., Ltd

Advantages: Hubei XinRunde Chemical Co., Ltd is a renowned pharmaceutical manufacturer. We can offer high quality products at competitive price in quick delivery with 100% custom pass guaranteed. Never stop striving to offer our best serv

(S)-3-(dimethylamino)-1-(3-methoxyphenyl)-2-methylpropan-1-one CAS:850222-40-1

Cas:850222-40-1

Min.Order:10 Gram

Negotiable

Type:Other

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

1-Propanone,3-(dimethylamino)-1-(3-methoxyphenyl)-2-methyl-, (2S)- 850222-40-1

Cas:850222-40-1

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At prese

Pharmaceutical Intermediate, (S)-3-(dimethylamino)-1-(3-methoxyphenyl)-2-methylpropan-1-one CAS:850222-40-1

Cas:850222-40-1

Min.Order:1 Gram

FOB Price: $42.0 / 45.0

Type:Trading Company

inquiry

Qingdao Beluga Import and Export Co., LTD

(S)-3-(dimethylamino)-1-(3-methoxyphenyl)-2-methylpropan-1-one CAS:850222-40-1 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediate

(S)-3-(dimethylamino)-1-(3-methoxyphenyl)-2-methylpropan-1-one CAS:850222-40-1

Cas:850222-40-1

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

1-Propanone,3-(dimethylamino)-1-(3-methoxyphenyl)-2-methyl-, (2S)-

Cas:850222-40-1

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Changchun Artel lmport and Export trade company

Superiority We can customize and synthesize products that other suppliers may not be able to provide. Advantage cof, mof ligand manufacturer Product Detail

Lonwin Chemical Group Limited

New production CAS: 850222-40-1 Specificatio Category Pharmaceutical Raw Materials, Fine Chemicals, Bulk drug Standard Medical standard Shelf life 2 years Storage should be stored in a well-clo

Factory supply New production

Cas:850222-40-1

Min.Order:1 Kilogram

FOB Price: $100.0 / 150.0

Type:Other

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

1-Propanone,3-(dimethylamino)-1-(3-methoxyphenyl)-2-methyl-, (2S)-

Cas:850222-40-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

(S)-3-(dimethylamino)-1-(3-methoxyphenyl)-2-methylpropan-1-one

Cas:850222-40-1

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Afine Chemicals Limited

Company Introduction 1. Established in 2005, with two independent business divisions: Fine chemicals division; Pharmaceutical division. 2. Main product: Optical brightener Textile auxiliary Dye stuff Pigments

(S)-3-DIMETHYLAMINO-1-(3-METHOXYPHENYL)-2-METHYL-1-PROPANONE

Cas:850222-40-1

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

SHANGHAI T&W PHARMACEUTICAL CO., LTD.

A substitute for perfluorooctanoic acid, mainly used as a surfactant, dispersant, additive, etc Appearance:White solid or Colorless liquid Purity:99.3 % We will ship the goods in a timely manner as required We can provide relevant documents acc

(S)-3-(dimethylamino)-1-(3-methoxyphenyl)-2-methylpropan-1-one

Cas:850222-40-1

Min.Order:4 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Saiwante (shanghai) New Material Technology Co., Ltd.

Vapor Pressure:0.000428mmHg at 25°C Refractive Index:1.508 Boiling Point:315.8 °C at 760 mmHg PKA:8.87±0.28(Predicted) Flash Point:144.8 °C PSA:29.54000 Density:1.012 g/cm3 LogP:2.07560 Storage Temp.:2-8°C

850222-40-1 (S)-3-(dimethylamino)-1-(3-methoxyphenyl)-2-methylpropan-1-one

Cas:850222-40-1

Min.Order:1 Gram

FOB Price: $6.0

Type:Trading Company

inquiry

Shanghai Hope Chem Co., Ltd

1. Product advantages: exquisite appearance and unique functions. 2. Product Advantages: Our products are the best,fast speed ,in large stock 3. High-quality products and thoughtful service are your greatest satisfaction. 4. The product

(S)-3-(Dimethylamino)-1-(3-methoxyphenyl)-2-methylpropan-1-one

Cas:850222-40-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

(s)-3-(dimethylamino)-1-(3-methoxyphenyl)-2-methoylpropan-1-one

Cas:850222-40-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

(2S)-3-(Dimethylamino)-1-(3-methoxyphenyl)-2-methyl-1-propanone CAS NO.850222-40-1

Cas:850222-40-1

Min.Order:10 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Lingrui Chemical Co.,Ltd.

(S)-3-(dimethylamino)-1-(3-methoxyphenyl)-2-methylpropan-1-oneAppearance:powder Storage:store in cool, dry place Package:according to customers' requirements Application:850222-40-1 Transportation:By air(EMS or EUB or FedEx or TNT ect...) or by sea(F

(S)-3-(dimethylamino)-1-(3-methoxyphenyl)-2-methylpropan-1-one

Cas:850222-40-1

Min.Order:1 Gram

Negotiable

Type:Other

inquiry

SHANGHAI SYSTEAM BIOCHEM CO., LTD

We are one of a few suppliers that can offer custom synthesis service of this product We are specialized in custom synthesis, chemical/pharmaceutical/ pesticides outsourcing and contract research. We are committed to prov

(S)-3-(dimethylamino)-1-(3-methoxyphenyl)-2-methylpropan-1-one

Cas:850222-40-1

Min.Order:100 Gram

FOB Price: $100.0 / 2000.0

Type:Lab/Research institutions

inquiry

HANGZHOU YUNUO CHEMICAL CO.,LTD

Superior quality, moderate price & quick delivery. Appearance:white powder Storage:Stored in cool, dry and ventilation place; Away from fire and heat Package:10g/bag,or as your request Application:Used for Pesticide intermediates Transport

(S)-3-Dimethylamino-1-(3-methoxyphenyl)-2-methyl-1-propanone

Cas:850222-40-1

Min.Order:1 Gram

Negotiable

Type:Trading Company

inquiry

Zibo Dorne chemical technology co. LTD

Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,

(S)-3-(dimethylamino)-1-(3-methoxyphenyl)-2-methylpropan-1-one

Cas:850222-40-1

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Siwei Development Group Ltd.

Product name: (S)-3-Dimethylamino-1-(3-Methoxyphenyl)-2-Methyl-1-Propanone CAS No.:850222-40-1 Molecule Formula:C13H19NO2 Molecule Weight:221.29 Purity: 99.0% Package: 25kg/drum Description:White powder Manufacture Standards:Enterprise Standar

Best Quality (S)-3-Dimethylamino-1-(3-Methoxyphenyl)-2-Methyl-1-Propanone

Cas:850222-40-1

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Xiamen Jenny Chemical Technology Co., Ltd.

GMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,

(S)-3-(dimethylamino)-1-(3-methoxyphenyl)-2-methylpropan-1-one

Cas:850222-40-1

Min.Order:1 Milligram

Negotiable

Type:Trading Company

inquiry

Synthetic route

(S)-3-(dimethylamino)-1-(3-methoxyphenyl)-2-methylpropan-1-one (2R,3R)-O,O'-dibenzoyltartrate
850222-41-2

(S)-3-(dimethylamino)-1-(3-methoxyphenyl)-2-methylpropan-1-one (2R,3R)-O,O'-dibenzoyltartrate

(2S)-3-dimethylamino-1-(3-methoxyphenyl)-2-methyl-1-propanone
850222-40-1

(2S)-3-dimethylamino-1-(3-methoxyphenyl)-2-methyl-1-propanone

Conditions
ConditionsYield
With diethylamine In tert-butyl methyl ether at 20 - 25℃; for 1.5h;96.5%
With diethylamine In tert-butyl methyl ether at 20℃; for 3h; Product distribution / selectivity;
With ammonia; water In 2-methyltetrahydrofuran for 0.5h; Product distribution / selectivity;
With diethylamine In tert-butyl methyl ether
formaldehyd
50-00-0

formaldehyd

1-(3-methoxyphenyl)propan-1-one
37951-49-8

1-(3-methoxyphenyl)propan-1-one

N,N-dimethylammonium chloride
506-59-2

N,N-dimethylammonium chloride

(2S)-3-dimethylamino-1-(3-methoxyphenyl)-2-methyl-1-propanone
850222-40-1

(2S)-3-dimethylamino-1-(3-methoxyphenyl)-2-methyl-1-propanone

Conditions
ConditionsYield
With hydrogenchloride; L-proline In ethanol; water for 16h; Reflux; Inert atmosphere;78%
3-(dimethylamino)-1-(3-methoxyphenyl)-2-methylpropan-1-one
197145-37-2

3-(dimethylamino)-1-(3-methoxyphenyl)-2-methylpropan-1-one

(2S)-3-dimethylamino-1-(3-methoxyphenyl)-2-methyl-1-propanone
850222-40-1

(2S)-3-dimethylamino-1-(3-methoxyphenyl)-2-methyl-1-propanone

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: acetone; methanol
2: diethylamine / tert-butyl methyl ether
View Scheme
1-(3-methoxyphenyl)propan-2-one
3027-13-2

1-(3-methoxyphenyl)propan-2-one

(2S)-3-dimethylamino-1-(3-methoxyphenyl)-2-methyl-1-propanone
850222-40-1

(2S)-3-dimethylamino-1-(3-methoxyphenyl)-2-methyl-1-propanone

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: trifluoroacetic acid
2: acetone; methanol
3: diethylamine / tert-butyl methyl ether
View Scheme
formaldehyd
50-00-0

formaldehyd

1-(3-methoxyphenyl)propan-1-one
37951-49-8

1-(3-methoxyphenyl)propan-1-one

dimethyl amine
124-40-3

dimethyl amine

(2S)-3-dimethylamino-1-(3-methoxyphenyl)-2-methyl-1-propanone
850222-40-1

(2S)-3-dimethylamino-1-(3-methoxyphenyl)-2-methyl-1-propanone

Conditions
ConditionsYield
With L-proline In ethanol at 77℃; for 36h; Temperature; Solvent; Mannich Aminomethylation;306.2 g
(2S)-3-dimethylamino-1-(3-methoxyphenyl)-2-methyl-1-propanone
850222-40-1

(2S)-3-dimethylamino-1-(3-methoxyphenyl)-2-methyl-1-propanone

ethylmagnesium bromide
925-90-6

ethylmagnesium bromide

(2S,3R)-1-(dimethylamino)-3-(3-methoxyphenyl)-2-methyl pentan-3-ol
809282-20-0

(2S,3R)-1-(dimethylamino)-3-(3-methoxyphenyl)-2-methyl pentan-3-ol

Conditions
ConditionsYield
Stage #1: (2S)-3-dimethylamino-1-(3-methoxyphenyl)-2-methyl-1-propanone; ethylmagnesium bromide In tetrahydrofuran at 15℃; for 4h; Grignard Reaction;
Stage #2: With ammonium bisulphate; water In tetrahydrofuran at 5℃; Product distribution / selectivity;
99%
(2S)-3-dimethylamino-1-(3-methoxyphenyl)-2-methyl-1-propanone
850222-40-1

(2S)-3-dimethylamino-1-(3-methoxyphenyl)-2-methyl-1-propanone

(2S,3R)-1-(dimethylamino)-3-(3-methoxyphenyl)-2-methyl pentan-3-ol
809282-20-0

(2S,3R)-1-(dimethylamino)-3-(3-methoxyphenyl)-2-methyl pentan-3-ol

Conditions
ConditionsYield
Stage #1: ethyl bromide With magnesium In diethyl ether at 35℃; for 2.5h;
Stage #2: (2S)-3-dimethylamino-1-(3-methoxyphenyl)-2-methyl-1-propanone In diethyl ether at 10 - 15℃; for 2h; Grignard Reaction;
Stage #3: With ammonium bisulphate; water In diethyl ether at 5℃; Product distribution / selectivity;
98%
(2S)-3-dimethylamino-1-(3-methoxyphenyl)-2-methyl-1-propanone
850222-40-1

(2S)-3-dimethylamino-1-(3-methoxyphenyl)-2-methyl-1-propanone

ethylmagnesium bromide
925-90-6

ethylmagnesium bromide

(2SS,3RS)-[3-(3-methoxy-phenyl)-2-methyl-pentan-3-ol]-dimethylamine

(2SS,3RS)-[3-(3-methoxy-phenyl)-2-methyl-pentan-3-ol]-dimethylamine

Conditions
ConditionsYield
Stage #1: (2S)-3-dimethylamino-1-(3-methoxyphenyl)-2-methyl-1-propanone; ethylmagnesium bromide In tetrahydrofuran; diethyl ether at 10 - 15℃; for 2h; Grignard Reaction;
Stage #2: With water; ammonium chloride In tetrahydrofuran; diethyl ether at 5℃;
71%
(2S)-3-dimethylamino-1-(3-methoxyphenyl)-2-methyl-1-propanone
850222-40-1

(2S)-3-dimethylamino-1-(3-methoxyphenyl)-2-methyl-1-propanone

ethylmagnesium chloride
2386-64-3

ethylmagnesium chloride

(2S,3R)-1-(dimethylamino)-3-(3-methoxyphenyl)-2-methyl pentan-3-ol
809282-20-0

(2S,3R)-1-(dimethylamino)-3-(3-methoxyphenyl)-2-methyl pentan-3-ol

Conditions
ConditionsYield
Stage #1: (2S)-3-dimethylamino-1-(3-methoxyphenyl)-2-methyl-1-propanone; ethylmagnesium chloride In tetrahydrofuran at 2 - 25℃; for 3.83333h; Grignard Reaction;
Stage #2: With water; acetic acid In tetrahydrofuran at 20℃; for 0.5h;
Stage #3: With ammonia; water In tetrahydrofuran at 20℃; for 0.166667h;
(2S)-3-dimethylamino-1-(3-methoxyphenyl)-2-methyl-1-propanone
850222-40-1

(2S)-3-dimethylamino-1-(3-methoxyphenyl)-2-methyl-1-propanone

(βR,γR)-γ-ethyl-N,N,β-trimethyl-3-methoxybenzenepropanamine
175591-22-7

(βR,γR)-γ-ethyl-N,N,β-trimethyl-3-methoxybenzenepropanamine

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: diethyl ether; tetrahydrofuran / 2 h / 10 - 15 °C
1.2: 5 °C
2.1: hydrogenchloride / water / 5 h / 55 °C
2.2: 20 °C / pH 12
3.1: hydrogenchloride; hydrogen / palladium 10% on activated carbon / ethanol; water / 20 °C / Inert atmosphere
View Scheme
(2S)-3-dimethylamino-1-(3-methoxyphenyl)-2-methyl-1-propanone
850222-40-1

(2S)-3-dimethylamino-1-(3-methoxyphenyl)-2-methyl-1-propanone

tapentadol hydrochloride

tapentadol hydrochloride

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1.1: diethyl ether; tetrahydrofuran / 2 h / 10 - 15 °C
1.2: 5 °C
2.1: hydrogenchloride / water / 5 h / 55 °C
2.2: 20 °C / pH 12
3.1: hydrogenchloride; hydrogen / palladium 10% on activated carbon / ethanol; water / 20 °C / Inert atmosphere
4.1: methanesulfonic acid; DL-methionine / 72 h / 80 °C
4.2: pH 10 - 12
5.1: hydrogenchloride / diethyl ether / 4 h
View Scheme
(2S)-3-dimethylamino-1-(3-methoxyphenyl)-2-methyl-1-propanone
850222-40-1

(2S)-3-dimethylamino-1-(3-methoxyphenyl)-2-methyl-1-propanone

tapentadol
175591-23-8

tapentadol

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: diethyl ether; tetrahydrofuran / 2 h / 10 - 15 °C
1.2: 5 °C
2.1: hydrogenchloride / water / 5 h / 55 °C
2.2: 20 °C / pH 12
3.1: hydrogenchloride; hydrogen / palladium 10% on activated carbon / ethanol; water / 20 °C / Inert atmosphere
4.1: methanesulfonic acid; DL-methionine / 72 h / 80 °C
4.2: pH 10 - 12
View Scheme
(2S)-3-dimethylamino-1-(3-methoxyphenyl)-2-methyl-1-propanone
850222-40-1

(2S)-3-dimethylamino-1-(3-methoxyphenyl)-2-methyl-1-propanone

(R)-3-(3-methoxyphenyl)-N,N,2-trimethylpent-3-en-1-amine

(R)-3-(3-methoxyphenyl)-N,N,2-trimethylpent-3-en-1-amine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: diethyl ether; tetrahydrofuran / 2 h / 10 - 15 °C
1.2: 5 °C
2.1: hydrogenchloride / water / 5 h / 55 °C
2.2: 20 °C / pH 12
View Scheme
(2S)-3-dimethylamino-1-(3-methoxyphenyl)-2-methyl-1-propanone
850222-40-1

(2S)-3-dimethylamino-1-(3-methoxyphenyl)-2-methyl-1-propanone

(R,R)-tapentadol-(PABA tert-butyl ester) carbamate
1314003-88-7

(R,R)-tapentadol-(PABA tert-butyl ester) carbamate

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1.1: diethyl ether; tetrahydrofuran / 2 h / 10 - 15 °C
1.2: 5 °C
2.1: hydrogenchloride / water / 5 h / 55 °C
2.2: 20 °C / pH 12
3.1: hydrogenchloride; hydrogen / palladium 10% on activated carbon / ethanol; water / 20 °C / Inert atmosphere
4.1: methanesulfonic acid; DL-methionine / 72 h / 80 °C
4.2: pH 10 - 12
5.1: toluene / Reflux
View Scheme
(2S)-3-dimethylamino-1-(3-methoxyphenyl)-2-methyl-1-propanone
850222-40-1

(2S)-3-dimethylamino-1-(3-methoxyphenyl)-2-methyl-1-propanone

(R,R)-tapentadol-PABA carbamate trifluoroacetate
1314003-30-9

(R,R)-tapentadol-PABA carbamate trifluoroacetate

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1.1: diethyl ether; tetrahydrofuran / 2 h / 10 - 15 °C
1.2: 5 °C
2.1: hydrogenchloride / water / 5 h / 55 °C
2.2: 20 °C / pH 12
3.1: hydrogenchloride; hydrogen / palladium 10% on activated carbon / ethanol; water / 20 °C / Inert atmosphere
4.1: methanesulfonic acid; DL-methionine / 72 h / 80 °C
4.2: pH 10 - 12
5.1: toluene / Reflux
6.1: 1 h / 20 °C
View Scheme

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