Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities
Cas:875781-17-2
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inquiryWelcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our
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inquiryManufacturer supply 5-Bromo-1H-pyrazolo[3,4-b]pyridine CAS 875781-17-2 with attractive price Company profile Wuhan Fortuna Chemical Co.,Ltd established in 2006, is a big integrative chemical enterprise being engaged in Pharmaceutical & its i
Cas:875781-17-2
Min.Order:10 Kilogram
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Type:Trading Company
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inquiryShanghai Seasonsgreen Chemical is a high-tech research and development, production, sale and custom synthesis set in one high-tech chemical products enterprises. Our sales and marketing division is located in Shanghai, serving international pharmaceu
Cas:875781-17-2
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Cas:875781-17-2
Min.Order:5 Kiloliter
FOB Price: $1.2 / 5.0
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Type:Trading Company
inquiryProducts: 5-Bromo-1H-pyrazolo[3,4-b]pyridine Cas No.: 875781-17-2 Molecular Formula: C6H4BrN3 Molecular Weight: 198.02 Assay: 98% HPLC Molecular Structure: Appearanc
Cas:875781-17-2
Min.Order:1 Kilogram
FOB Price: $1.0
Type:Other
inquiry1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; Appearance:powder Storage:Store in sealed containers at cool & dry plac
Cas:875781-17-2
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Min.Order:1 Kilogram
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inquiry5-BROMO-1H-PYRAZO[3,4-B]PYRIDINE CAS:875781-17-2 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality
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Min.Order:1 Gram
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Type:Lab/Research institutions
inquiryHello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai
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Min.Order:1 Kilogram
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inquiryHenan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod
Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia
Appearance:white or light yellow crystalline powder Storage:Store in a cool,dry place and keep away from direct strong light Package:As customer request Application:Used for research and industrial manufacture. Transportation:By Se
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Min.Order:0 Metric Ton
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inquiryA substitute for perfluorooctanoic acid, mainly used as a surfactant, dispersant, additive, etc Appearance:White solid or Colorless liquid Purity:99.3 % We will ship the goods in a timely manner as required We can provide relevant documents acc
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inquiryCompany Introduction 1. Established in 2005, with two independent business divisions: Fine chemicals division; Pharmaceutical division. 2. Main product: Optical brightener Textile auxiliary Dye stuff Pigments
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Min.Order:1 Gram
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Type:Lab/Research institutions
inquiryHot sale 875781-17-2 Top quality 5-Bromo-1H-pyrazolo[3,4-b]pyridine manufacturer 5-bromo-1H-pyrazolo [3,4-B] pyridine Chinese alias 5-bromopyrazolo [3,4-b] pyridine, pyrazolo [3,4-B] pyridine compound is a very important kind of thick heterocyclic
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Min.Order:1 Gram
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Type:Other
inquiryJ&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia
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inquiryZibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi
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Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiry5-BROMO-1H-PYRAZO[3,4-B]PYRIDINE Basic information Product Name: 5-BROMO-1H-PYRAZO[3,4-B]PYRIDINE Synonyms: 5-bromo-1H-pyrazoio[3,4-b]pyridine;5-Bromopyrazolo[3,4-b]pyridine;5-Bromo-1H-pyrazolo[3,4-b]pyridine;1H-Pyrazolo[3,4-b]pyridine, 5-broM
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Min.Order:1 Gram
Negotiable
Type:Lab/Research institutions
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inquirySAGECHEM is a chemical R&D, manufacturing and distribution company in China since 2009, including pharmaceutical intermediates, agrochemical, dyestuff intermediates, organosilicone, API and etc. We also offer a full range of services in custom synthe
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inquiryGOLDEN PHARMA CO.,LIMITED.is a professional pharmaceutical company,our team have more than 20years expereince in pharmaceutical production and sales. we are a professional technical enterprise specializing in the R & D, production,QA regulation
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inquirySuperior quality, moderate price & quick delivery. Appearance:white powder Storage:stored in a cool, dry and ventilated place to provent sun and rain Package:25kg/drum, or as per your request. Application:Used as Pharmaceutical Intermediate
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Min.Order:1 Kilogram
Negotiable
Type:Trading Company
inquiryShanghai Finebiotech Co.,Ltd.was established in 2020, which providing professional chemical services. As a customer-oriented company, we have distinguished ourself from others in providing worldwide customers with cost-effective and efficient service
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inquiry5-bromo-2-fluoro-pyridine-3-carbaldehyde
5-bromo-7-azaindazole
Conditions | Yield |
---|---|
With hydrazine hydrate In water at 65℃; for 15h; Inert atmosphere; | 82% |
With hydrazine In ethanol Heating / reflux; | 46% |
With hydrazine hydrate In ethanol at 100℃; for 8h; | 40% |
5-bromo-7-azaindazole
Conditions | Yield |
---|---|
Stage #1: C12H18BrN3O2*ClH With hydrogenchloride In ethanol; water at 20 - 65℃; for 16h; Stage #2: With sodium carbonate In ethanol; water | 50% |
Conditions | Yield |
---|---|
In acetic acid for 6h; Heating; Reflux; Inert atmosphere of N2; | 25% |
2-Bromo-malonaldehyde
3(5)-aminopyrazole
A
6-bromo-pyrazolo[1,5-α]pyrimidine
B
5-bromo-7-azaindazole
Conditions | Yield |
---|---|
In ethanol at 20℃; Heating / reflux; | A 13.8% B 2.1% |
Conditions | Yield |
---|---|
With acetic acid for 2h; Heating / reflux; | 11% |
C8H10BrN3O2*ClH
5-bromo-7-azaindazole
Conditions | Yield |
---|---|
Stage #1: C8H10BrN3O2*ClH With hydrogenchloride In ethanol; water at 20 - 65℃; for 16h; Stage #2: With sodium hydrogencarbonate In ethanol; water pH=8; |
5-bromo-3-(4,4,5,5-tetramethyl-1,3-dioxolan-2-yl)-2(1H)-pyridinone hydrazone
5-bromo-7-azaindazole
Conditions | Yield |
---|---|
With hydrogenchloride; water In ethanol at 20 - 60℃; |
5-bromo-2-fluoropyridine
5-bromo-7-azaindazole
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1.1: N-ethyl-N,N-diisopropylamine; n-butyllithium / tetrahydrofuran / 0.5 h / -78 °C 1.2: 0.17 h / -78 °C 2.1: hydrazine hydrate / ethanol / 8 h / 100 °C View Scheme | |
Multi-step reaction with 2 steps 1.1: diisopropylamine; n-butyllithium / tetrahydrofuran / 3 h / -65 - -30 °C / Inert atmosphere 1.2: 0.08 h 2.1: hydrazine hydrate / tetrahydrofuran; ethanol; water / 1 h / 45 - 80 °C / Large scale View Scheme | |
Multi-step reaction with 2 steps 1.1: lithium diisopropyl amide / tetrahydrofuran / 1 h / -90 - -85 °C 1.2: 0.5 h / -80 °C 2.1: hydrazine hydrate / ethanol / 12 h / 75 - 80 °C View Scheme |
3,4-dihydro-2H-pyran
5-bromo-7-azaindazole
Conditions | Yield |
---|---|
With pyridinium p-toluenesulfonate In dichloromethane; acetonitrile at 20℃; for 24h; | 100% |
With toluene-4-sulfonic acid In toluene at 100℃; for 4h; | 98% |
With toluene-4-sulfonic acid at 25 - 30℃; for 3h; | 60.7% |
5-bromo-7-azaindazole
5-bromo-3-iodo-1H-pyrazolo[3,4-b]pyridine
Conditions | Yield |
---|---|
Stage #1: 5-bromo-7-azaindazole With iodine; potassium hydroxide In N,N-dimethyl-formamide for 3.5h; Stage #2: With iodine; sodium hydroxide In 1,4-dioxane at 40℃; for 23h; | 97% |
Stage #1: 5-bromo-7-azaindazole With potassium hydroxide In N,N-dimethyl-formamide for 0.166667h; Stage #2: With iodine In N,N-dimethyl-formamide at 20℃; for 3.5h; | 96% |
Stage #1: 5-bromo-7-azaindazole With iodine; potassium hydroxide In N,N-dimethyl-formamide at 20℃; for 1h; Stage #2: With iodine In N,N-dimethyl-formamide at 45℃; for 1h; | 92% |
5-bromo-7-azaindazole
di-tert-butyl dicarbonate
Conditions | Yield |
---|---|
With dmap; triethylamine In acetonitrile at 20℃; for 3.25h; Inert atmosphere; | 93% |
With dmap; triethylamine In dichloromethane at 20℃; for 24h; | 85% |
With dmap In tetrahydrofuran for 14h; Reflux; | 68% |
5-bromo-7-azaindazole
hexamethylenetetramine
Conditions | Yield |
---|---|
With acetic acid In water for 12h; Sommelet Aldehyde Synthesis; Reflux; | 92% |
5-bromo-7-azaindazole
Conditions | Yield |
---|---|
With 3-chloro-benzenecarboperoxoic acid In ethyl acetate at 20 - 50℃; for 5.5h; | 91% |
With dihydrogen peroxide; trifluoroacetic acid at 60℃; for 12h; |
zinc(II) cyanide
5-bromo-7-azaindazole
Conditions | Yield |
---|---|
With tetrakis(triphenylphosphine) palladium(0) In 1-methyl-pyrrolidin-2-one at 92℃; for 5h; Temperature; | 90% |
With tris(dibenzylideneacetone)dipalladium(0) chloroform complex; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene In N,N-dimethyl acetamide; water at 80℃; for 6h; Inert atmosphere; | 82% |
With tris-(dibenzylideneacetone)dipalladium(0); XPhos In water; N,N-dimethyl-formamide at 100℃; for 12h; Inert atmosphere; | 82% |
With tetrakis(triphenylphosphine) palladium(0) In N,N-dimethyl-formamide at 85℃; for 10h; Inert atmosphere; Large scale; | 535 g |
5-bromo-7-azaindazole
[3-(morpholin-4-ylcarbonyl)phenyl]boronic acid
A
morpholin-4-yl-[3-(1H-pyrazolo[3,4-b]pyridin-5-yl)-phenyl]-methanone
B
Triphenylphosphine oxide
Conditions | Yield |
---|---|
With sodium carbonate; tetrakis(triphenylphosphine) palladium(0) In 1,2-dimethoxyethane; water at 175℃; for 1h; Microwave irradiation; | A 80% B 20% |
5-bromo-7-azaindazole
p-methoxybenzyl chloride
5-bromo-1-(4-methoxybenzyl)-1H-pyrazolo[3,4-b]pyridine
Conditions | Yield |
---|---|
Stage #1: 5-bromo-7-azaindazole With sodium hydride In N,N-dimethyl-formamide at 0℃; for 0.5h; Stage #2: p-methoxybenzyl chloride In N,N-dimethyl-formamide at 0 - 20℃; | 77.2% |
With sodium hydride In N,N-dimethyl-formamide; mineral oil at 0 - 20℃; | 68.3% |
5-bromo-7-azaindazole
trimethylsilylacetylene
5-((trimethylsilyl) ethynyl)-1H-pyrazolo[3,4-b]pyridine
Conditions | Yield |
---|---|
With copper(l) iodide; tetrakis(triphenylphosphine) palladium(0); N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 20℃; for 1h; Inert atmosphere; | 73.7% |
With copper(l) iodide; tetrakis(triphenylphosphine) palladium(0); N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 20℃; for 1h; Inert atmosphere; | 73.7% |
With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine In acetonitrile for 20h; Reflux; Inert atmosphere; | 63% |
With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine In acetonitrile at 20 - 100℃; for 20h; Sonogashira Cross-Coupling; Inert atmosphere; | |
With copper(l) iodide; palladium bis[bis(diphenylphosphino)ferrocene] dichloride; triethylamine In N,N-dimethyl-formamide at 70℃; for 2h; Inert atmosphere; | 3.5 g |
5-bromo-7-azaindazole
(2-trimethylethylsilylethoxy)methyl chloride
5-bromo-1-{[2-(trimethylsilyl)ethoxy]methyl}-1H-pyrazolo[3,4-b]pyridine
Conditions | Yield |
---|---|
Stage #1: 5-bromo-7-azaindazole With sodium hydride In N,N-dimethyl-formamide at 0℃; for 0.5h; Stage #2: (2-trimethylethylsilylethoxy)methyl chloride In N,N-dimethyl-formamide at 20℃; for 0.5h; | 73% |
Stage #1: 5-bromo-7-azaindazole With sodium hydride In tetrahydrofuran; mineral oil at 0℃; for 0.166667h; Stage #2: (2-trimethylethylsilylethoxy)methyl chloride In tetrahydrofuran; mineral oil at 20℃; | 43% |
Stage #1: 5-bromo-7-azaindazole With sodium hydride In N,N-dimethyl-formamide; mineral oil at 0 - 20℃; for 0.416667h; Stage #2: (2-trimethylethylsilylethoxy)methyl chloride In N,N-dimethyl-formamide; mineral oil at 0℃; for 2h; Stage #3: With ammonium chloride In water; N,N-dimethyl-formamide; mineral oil Cooling; |
5-bromo-7-azaindazole
methyl iodide
5-bromo-1-methyl-1H-pyrazolo[3,4-b]pyridine
Conditions | Yield |
---|---|
Stage #1: 5-bromo-7-azaindazole With sodium hydride In tetrahydrofuran at 0℃; for 0.5h; Inert atmosphere; Stage #2: methyl iodide at 25℃; Inert atmosphere; | 73% |
5-bromo-7-azaindazole
propane-1-sulfonic acid {2,4-difluoro-3-[5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]-phenyl}-amide
propane-1-sulfonic acid {2,4-difluoro-3-[5-(1H-pyrazolo[3,4-b]pyridin-5-yl)-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]-phenyl}-amide
Conditions | Yield |
---|---|
With potassium carbonate; tetrakis(triphenylphosphine) palladium(0) In tetrahydrofuran; water; acetonitrile at 145℃; for 0.75h; microwave irradiation; | 72% |
5-bromo-7-azaindazole
methyl iodide
A
5-bromo-1-methyl-1H-pyrazolo[3,4-b]pyridine
Conditions | Yield |
---|---|
With sodium hexamethyldisilazane In tetrahydrofuran at 20℃; for 2h; | A 7% B 69% |
With sodium hexamethyldisilazane In tetrahydrofuran; dimethyl sulfoxide at 20℃; for 3h; | A 46% B 3% |
5-bromo-7-azaindazole
2-(tert-butyldimethylsilyloxy)ethyl bromide
Conditions | Yield |
---|---|
With caesium carbonate In N,N-dimethyl-formamide at 18 - 25℃; | 66% |
N-iodo-succinimide
5-bromo-7-azaindazole
5-bromo-3-iodo-1H-pyrazolo[3,4-b]pyridine
Conditions | Yield |
---|---|
In 1,2-dichloro-ethane Reflux; | 65.8% |
5-bromo-7-azaindazole
[3-(methoxycarbonyl)phenyl]boronic acid
methyl 3-(1H-pyrazolo[3,4-b]pyridin-5-yl)benzoate
Conditions | Yield |
---|---|
With sodium carbonate; tetrakis(triphenylphosphine) palladium(0) In 1,4-dioxane; water at 110℃; for 15h; Microwave irradiation; | 65% |
5-bromo-7-azaindazole
Conditions | Yield |
---|---|
With copper(l) iodide; tri-tert-butyl phosphine; potassium carbonate; bis(dibenzylideneacetone)-palladium(0) In tetrahydrofuran; toluene at 120℃; for 24h; Sonogashira Cross-Coupling; Sealed tube; Inert atmosphere; | 64% |
5-bromo-7-azaindazole
Conditions | Yield |
---|---|
With copper(l) iodide; tri-tert-butyl phosphine; potassium carbonate; bis(dibenzylideneacetone)-palladium(0) In tetrahydrofuran; toluene at 120℃; for 24h; Sonogashira Cross-Coupling; Sealed tube; Inert atmosphere; | 63% |
With copper(l) iodide; bis(di-tert-butyl(4-dimethylaminophenyl)phosphine)dichloropalladium(II); triethylamine In dimethyl sulfoxide at 120℃; for 1h; Sonogashira Cross-Coupling; Microwave irradiation; | 61% |
With copper(l) iodide; bis(di-tert-butyl(4-dimethylaminophenyl)phosphine)dichloropalladium(II); triethylamine In dimethyl sulfoxide at 120℃; for 1h; Microwave irradiation; | 2.15 g |
(2-(6-methylpyridin-2-yl)-5,6-dihydro-4Hpyrrolo[1,2-b]pyrazol-3-yl)boronic acid
5-bromo-7-azaindazole
Conditions | Yield |
---|---|
With sodium hydrogencarbonate; tetrakis(triphenylphosphine) palladium(0) In water; dimethyl sulfoxide at 110℃; for 0.166667h; Microwave irradiation; | 56% |
5-bromo-7-azaindazole
3,5-dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)isoxazole
Conditions | Yield |
---|---|
With palladium bis[bis(diphenylphosphino)ferrocene] dichloride; potassium carbonate In water; acetonitrile at 110℃; for 0.25h; Microwave irradiation; | 55% |
methanol
5-bromo-7-azaindazole
carbon monoxide
1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid methyl ester
Conditions | Yield |
---|---|
With 1,1'-bis-(diphenylphosphino)ferrocene; palladium diacetate; triethylamine In N,N-dimethyl-formamide at 100℃; for 12h; | 46% |
With palladium diacetate; triethylamine; 4,5-bis(diphenylphos4,5-bis(diphenylphosphino)-9,9-dimethylxanthenephino)-9,9-dimethylxanthene In N,N-dimethyl-formamide at 100℃; for 12h; |
Conditions | Yield |
---|---|
With tris[2-phenylpyridinato-C2,N]iridium(III); copper acetylacetonate; N,N,N′,N′-tetramethyl-N″-tert-butylguanidine In 1,4-dioxane Irradiation; | 46% |
5-bromo-7-azaindazole
Conditions | Yield |
---|---|
With copper(l) iodide; tetrabutyl ammonium fluoride; triethylamine In N,N-dimethyl-formamide Heating; | 42% |
5-bromo-7-azaindazole
7-amino-3-bromo-1-cyclopentyl-5-methyl-1,6-naphthyridin-2(1H)-one
7-amino-1-cyclopentyl-5-methyl-3-(1H-pyrazolo[3,4-b]pyridin-5-yl)-1,6-naphthyridin-2(1H)-one
Conditions | Yield |
---|---|
Stage #1: 5-bromo-7-azaindazole With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium acetate; bis(pinacol)diborane In 1,4-dioxane at 100℃; for 3h; Inert atmosphere; Stage #2: 7-amino-3-bromo-1-cyclopentyl-5-methyl-1,6-naphthyridin-2(1H)-one With potassium carbonate In 1,4-dioxane; water at 100℃; for 3h; Inert atmosphere; | 28% |
5-bromo-7-azaindazole
Conditions | Yield |
---|---|
With dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2; sodium carbonate In water; acetonitrile at 100℃; for 3h; Inert atmosphere; | 28% |
5-bromo-7-azaindazole
2-(4-morpholinyl)-7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)quinoxaline
2-(4-morpholinyl)-7-(1H-pyrazolo[3,4-b]pyridin-5-yl)quinoxaline
Conditions | Yield |
---|---|
With sodium carbonate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride In 1,4-dioxane; water at 110℃; for 18h; | 26% |
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