1015609-83-2 Usage
Description
4-Chloro-5-iodo-1-(triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridine is a complex organic compound characterized by its bicyclic heteroaromatic structure. It features a pyrrolo[2,3-b]pyridine core with a chloro group at the 4-position and an iodo group at the 5-position, as well as a triisopropylsilyl substituent attached to the nitrogen atom. 4-CHLORO-5-IODO-1-(TRIISOPROPYLSILYL)-1H-PYRROLO[2,3-B]PYRIDINE is known for its potential applications in the pharmaceutical industry, particularly as a building block for the synthesis of various biologically active molecules.
Uses
Used in Pharmaceutical Industry:
4-Chloro-5-iodox-1-(triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridine is used as a reactant in the synthesis of bicyclic heteroaromatic compounds, which are known to act as kinase inhibitors. Kinase inhibitors are essential in the development of targeted therapies for various diseases, including cancer and other proliferative disorders. The compound's unique structure allows for the creation of potent and selective inhibitors that can modulate the activity of specific kinases, thereby disrupting the signaling pathways involved in disease progression.
In the synthesis of bicyclic heteroaromatic compounds, 4-chloro-5-iodo-1-(triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridine serves as a key intermediate, providing a versatile platform for further functionalization and optimization. The resulting kinase inhibitors can be tailored to exhibit improved potency, selectivity, and pharmacokinetic properties, making them valuable candidates for drug development.
Overall, 4-chloro-5-iodo-1-(triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridine is a promising compound in the field of medicinal chemistry, with potential applications in the development of novel therapeutic agents for the treatment of various diseases, particularly those involving dysregulated kinase activity.
Check Digit Verification of cas no
The CAS Registry Mumber 1015609-83-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,1,5,6,0 and 9 respectively; the second part has 2 digits, 8 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1015609-83:
(9*1)+(8*0)+(7*1)+(6*5)+(5*6)+(4*0)+(3*9)+(2*8)+(1*3)=122
122 % 10 = 2
So 1015609-83-2 is a valid CAS Registry Number.
1015609-83-2Relevant articles and documents
Compound with pyrrolopyridine structure, preparation method and medical application
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, (2021/08/06)
The invention discloses a compound with a pyrrolopyridine structure, a preparation method and medical application. The compound with the pyrrolopyridine structure has obvious inhibitory activity on JAK family proteins, and is an effective JAK inhibitor, so that the compound has a prospect of being developed into drugs for inhibiting JAK and further treating diseases.
BICYCLIC HETEROAROMATIC COMPOUNDS
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, (2015/09/22)
Compounds of the formula I, in which X1, X2, X3, X4, X5, R1, R2, R3, R4, R5 and R6 have the meanings indicated in Claim 1, are kinase inhibitors and can be employed, inter alia, for the treatment of tumours.
