1196507-56-8 Usage
Description
1H-Pyrrolo[2,3-b]pyridine, 4-chloro-5-iodo-1-(phenylsulfonyl)is a complex organic compound characterized by its unique molecular structure, which features a pyrrolo[2,3-b]pyridine core with a 4-chloro-5-iodo substitution pattern and a phenylsulfonyl group attached to the nitrogen atom. 1H-Pyrrolo[2,3-b]pyridine, 4-chloro-5-iodo-1-(phenylsulfonyl)is known for its potential applications in the pharmaceutical and chemical synthesis industries due to its versatile chemical properties and reactivity.
Uses
Used in Pharmaceutical Industry:
1H-Pyrrolo[2,3-b]pyridine, 4-chloro-5-iodo-1-(phenylsulfonyl)is used as a reactant in the synthesis of N-azaindolyl pyrazolecarboxamides, which are known as CHK1 inhibitors. These inhibitors play a crucial role in the regulation of cell cycle progression and have potential applications in the development of anticancer therapies. By targeting CHK1, these inhibitors can help in the treatment of various types of cancer by disrupting the cell cycle and preventing the proliferation of cancer cells.
Used in Chemical Synthesis:
In the field of chemical synthesis, 1H-Pyrrolo[2,3-b]pyridine, 4-chloro-5-iodo-1-(phenylsulfonyl)serves as an intermediate or building block for the creation of more complex organic molecules. Its unique structure and functional groups make it a valuable component in the synthesis of various pharmaceuticals, agrochemicals, and other specialty chemicals. 1H-Pyrrolo[2,3-b]pyridine, 4-chloro-5-iodo-1-(phenylsulfonyl)-'s reactivity and versatility allow chemists to explore new synthetic routes and develop innovative applications for this molecule.
Check Digit Verification of cas no
The CAS Registry Mumber 1196507-56-8 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,9,6,5,0 and 7 respectively; the second part has 2 digits, 5 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1196507-56:
(9*1)+(8*1)+(7*9)+(6*6)+(5*5)+(4*0)+(3*7)+(2*5)+(1*6)=178
178 % 10 = 8
So 1196507-56-8 is a valid CAS Registry Number.
1196507-56-8Relevant articles and documents
1H-PYRROLO[2,3-B] PYRIDINE DERIVATIVES AND THEIR USE AS KINASE INHIBITORS
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, (2015/02/18)
The inventions relates to compounds of (I) and therapeutic uses thereof: (I) The terms Z, Y, and R1 are as defined in the claims.
PYRROLOPYRIDINES AS KINASE INHIBITORS
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, (2009/12/23)
Compounds of Formula (I) are useful for inhibition of CHKl and/or CHK2. Methods of using compounds of Formula (I) and stereoisomers and pharmaceutically acceptable salts thereof, for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions are disclosed.
