101649-96-1

Basic information

• Product Name: (S)-4-(2-methoxymethyl)pyrrolidino-5,6-dihydro-2H-thiopyran
• Synonyms: (S)-4-(2-methoxymethyl)pyrrolidino-5,6-dihydro-2H-thiopyran
• CAS NO: 101649-96-1
• Molecular Weight: 213.344
• Mol File: 101649-96-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-4-(2-methoxymethyl)pyrrolidino-5,6-dihydro-2H-thiopyran(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-4-(2-methoxymethyl)pyrrolidino-5,6-dihydro-2H-thiopyran(101649-96-1)
• EPA Substance Registry System: (S)-4-(2-methoxymethyl)pyrrolidino-5,6-dihydro-2H-thiopyran(101649-96-1)

Safety Data

• Hazardous Substances Data: 101649-96-1(Hazardous Substances Data)

Upstream product

• 1072-72-6 Tetrahydrothiopyran-4-one 
• 63126-47-6 (2S)-2-(methoxymethyl)-1-pyrrolidine 

Downstream Products

• 101649-97-2 (+)-menthyl (1'S,2R)-2-benzoylamino-3-methyl-4-oxocaproate 
• 101694-79-5 (-)-menthyl (1'R,2S)-2-benzoylamino-2-(4-oxotetrahydrothiopyran-3-yl)acetate 
• 101649-95-0 (+)-menthyl (1'S,2R)-2-benzoylamino-2-(4-oxotetrahydrothiopyran-3-yl)acetate 

Relevant articles and documents

SYNTHESIS OF DIASTEREO- AND ENANTIOMERICALLY PURE α-AMINO-γ-OXO ACID ESTERS BY REACTION OF ACYLIMINOACETATES WITH ENAMINES DERIVED FROM 6-MEMBERED KETONES

A new efficient diastereo- and enantioselective synthesis of α-amino-γ-oxo acid esters by reaction of acyliminoacetates with enamines is described.By employing the concept of double stereodifferentiation, complete asymmetric induction (de=ee >/= 99.9 percent) for the C-C bond formation is obtained.Desulphurization of a sulphur containing product leads to the corresponding acyclic amino acid derivatives.The virtually complete anti-diastereo- and enantioselectivities are interpreted by a Diels-Alder like transition state.