1020110-72-8

Basic information

• Product Name: 2-amino-4-methyl-1H-pyrrole-3-carboxamide
• Synonyms: 2-amino-4-methyl-1H-pyrrole-3-carboxamide
• CAS NO: 1020110-72-8
• Molecular Weight: 139.157
• Mol File: 1020110-72-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-amino-4-methyl-1H-pyrrole-3-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-amino-4-methyl-1H-pyrrole-3-carboxamide(1020110-72-8)
• EPA Substance Registry System: 2-amino-4-methyl-1H-pyrrole-3-carboxamide(1020110-72-8)

Safety Data

• Hazardous Substances Data: 1020110-72-8(Hazardous Substances Data)

Upstream product

• 3416-57-7 N-acetonylphthalimide 
• 107-91-5 cyanoacetic acid amide 

Downstream Products

• 1618-37-7 5-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-ol 
• 1618-36-6 4-chloro-5-methyl-7H-pyrrolo[2,3-d]pyrimidine 

Relevant articles and documents

One-pot synthesis of 5-methyl-3H-pyrrolo[2,3-d]pyrimidin-4(7H)-one

An efficient and environmentally benign synthesis of 5-methyl-3H-pyrrolo[2, 3-d]pyrimidin-4(7H)-one is described. An acyl-protected aminoacetone is reacted with cyanoacetamide to give 2-amino-4-methyl-1H-pyrrole-3-carboxamide, which is converted in one-pot to 5-methyl-3H-pyrrolo[2,3-d]pyrimidin-4(7H)-one in 60% overall yield. This process avoids the use of large excess Raney nickel which is required when known methods are practiced.