10557-20-7Relevant articles and documents
An expedient protocol for conversion of olefins to α-bromo/iodoketones using IBX and NBS/NIS
Moorthy, Jarugu Narasimha,Senapati, Kalyan,Singhal, Nidhi
, p. 2493 - 2496 (2009)
A variety of olefins have been shown to undergo conversion to the corresponding α-bromo/iodoketones when reacted with NBS/NIS and IBX in DMSO at room temperature. While the reaction is found to occur rapidly with e-rich arylolefins leading to the corresponding haloketones in 65-95% yields in 0.3-3.0 h, those containing e-withdrawing groups are found to yield diketones concomitantly, such that the latter are the exclusive products over extended duration of the reactions.
Rapid microwave-promoted solvent-free oxidation of α-methylene ketones to α-diketones
Lee, Jong Chan,Park, Hong-Jun,Park, Jin Young
, p. 5661 - 5664 (2002)
A convenient and rapid method for the oxidation of α-methylene ketones to α-diketones has been described involving the reaction of pyridine N-oxide with α-nosyloxy ketone intermediates.
Synthesis of 1,2-diketones from β-keto nitriles via a protection-oxidative-decyanation-deprotection protocol
Liu, Yu,Yun, Xiliu,Zhang-Negrerie, Daisy,Huang, Jianhui,Du, Yunfei,Zhao, Kang
, p. 2984 - 2994 (2011/11/04)
A variety of 1,2-diketones were prepared from -keto nitriles via a three-step protocol including the protection of the ketones with methoxyamine, oxidative decyanation, and microwave-assisted deprotection in the final step. This approach provides a novel and efficient access to a wide scope of symmetric and unsymmetric 1,2-diketones using molecular oxygen as the oxidant in the decyanation process. Georg Thieme Verlag Stuttgart - New York.
Gold-catalyzed oxidation of arylallenes: Synthesis of quinoxalines and benzimidazoles
Cui, Dong-Mei,Zhuang, Dan-Wen,Chen, Ying,Zhang, Chen
experimental part, p. 860 - 865 (2011/08/05)
A gold-catalyzed oxidation of arylallenes to form α-diketones and aldehydes in good yields is presented. Further directed synthesis of quinoxalines and benzimidazoles, via the condensation of the resulting α-diketones and aldehydes with benzene-1,2-diamine, was achieved in high yields.