1070892-55-5

Basic information

• Product Name: 4-[5-chloro-4-(4-cyano-6-trifluoromethyl-pyridin-3-yl)-2-(methyl-o-tolyl-carbamoyl)-phenoxy]-butyric acid tert-butyl ester
• Synonyms: 4-[5-chloro-4-(4-cyano-6-trifluoromethyl-pyridin-3-yl)-2-(methyl-o-tolyl-carbamoyl)-phenoxy]-butyric acid tert-butyl ester
• CAS NO: 1070892-55-5
• Molecular Weight: 588.026
• Mol File: 1070892-55-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-[5-chloro-4-(4-cyano-6-trifluoromethyl-pyridin-3-yl)-2-(methyl-o-tolyl-carbamoyl)-phenoxy]-butyric acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4-[5-chloro-4-(4-cyano-6-trifluoromethyl-pyridin-3-yl)-2-(methyl-o-tolyl-carbamoyl)-phenoxy]-butyric acid tert-butyl ester(1070892-55-5)
• EPA Substance Registry System: 4-[5-chloro-4-(4-cyano-6-trifluoromethyl-pyridin-3-yl)-2-(methyl-o-tolyl-carbamoyl)-phenoxy]-butyric acid tert-butyl ester(1070892-55-5)

Safety Data

• Hazardous Substances Data: 1070892-55-5(Hazardous Substances Data)

Upstream product

• 749875-16-9 5-bromo-2-(trifluoromethyl)pyridine-4-carboxylic acid 
• 436799-32-5 5-bromo-2(trifluoromethyl)pyridine 
• 611-21-2 N,2-dimethylaniline 
• 110661-91-1 tert-butyl 4-bromobutyrate 
• 35112-05-1 4-chloro-2-fluoro-5-nitro-benzoic acid 
• 1070892-53-3 4-[4-bromo-5-chloro-2-(methyl-o-tolyl-carbamoyl)-phenoxy]-butyric acid tert-butyl ester 
• 1070892-48-6 4-chloro-2-fluoro-N-methyl-5-nitro-N-o-tolyl-benzamide 
• 1070892-49-7 5-amino-4-chloro-2-fluoro-N-methyl-N-o-tolyl-benzamide 
• 1070892-52-2 5-bromo-4-chloro-2-hydroxy-N-methyl-N-o-tolyl-benzamide 
• 1070892-51-1 5-bromo-4-chloro-2-methoxy-N-methyl-N-o-tolyl-benzamide 
• 1070892-50-0 5-bromo-4-chloro-2-fluoro-N-methyl-N-o-tolyl-benzamide 
• 947311-91-3 4-chloro-2-fluoro-5-nitro-benzoyl chloride 
• 1070892-03-3 5-bromo-2-trifluoromethylisonicotinamide 
• 1070892-04-4 5-bromo-2-trifluoromethylisonicotinonitrile 

Downstream Products

• 1070890-41-3 4-[5-chloro-4-(4-cyano-6-trifluoromethyl-pyridin-3-yl)-2-(methyl-o-tolyl-carbamoyl)-phenoxy]-butyric acid 

Relevant articles and documents

GONADOTROPIN-RELEASING HORMONE RECEPTOR ANTAGONISTS AND METHODS RELATING THERETO

GnRH receptor antagonists are disclosed which have utility in the treatment of a variety of sex-hormone related conditions in both men and women. The compounds of this invention have the structure, wherein R1a, R1b, R1c, R1d, R2, R2a, and A are as defined herein, including stereoisomers, esters, solvates and pharmaceutically acceptable salts thereof. Also disclosed are compositions containing a compound of this invention in combination with a pharmaceutically acceptable carrier, as well as methods relating to the use thereof for antagonizing gonadotropin-releasing hormone in a subject in need thereof.