107832-06-4

Basic information

• Product Name: (R)-2-hydroxy-4-phenylbutyric acid benzyl ester
• Synonyms: (R)-2-hydroxy-4-phenylbutyric acid benzyl ester
• CAS NO: 107832-06-4
• Molecular Weight: 270.328
• Mol File: 107832-06-4.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: (R)-2-hydroxy-4-phenylbutyric acid benzyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-2-hydroxy-4-phenylbutyric acid benzyl ester(107832-06-4)
• EPA Substance Registry System: (R)-2-hydroxy-4-phenylbutyric acid benzyl ester(107832-06-4)

Safety Data

• Hazardous Substances Data: 107832-06-4(Hazardous Substances Data)

Upstream product

• 1760-46-9 diphenylacetic anhydride 
• 109684-03-9 benzyl 2(R)-hydroxy-4-phenylbutyrate 
• 29678-81-7 (R)-2-hydroxy4-phenylbutanoic acid 
• 100-39-0 benzyl bromide 

Downstream Products

• 138333-10-5 (R)-4-Phenyl-2-trifluoromethanesulfonyloxy-butyric acid benzyl ester 
• 1345219-62-6 N-[1-(S)-benzyloxycarbonyl-3-phenylpropyl]-L-4,4'-biphenylalanine benzyl ester 
• 1345219-53-5 N-[1-(S)-benzyloxycarbonyl-3-phenylpropyl]-L-4-methylphenylalanyl-α-(S)-methyl-β-alanine benzyl ester 
• 1345219-51-3 N-[1-(S)-benzyloxycarbonyl-3-phenylpropyl]-L-4,4'-biphenylalanyl-α-(S)-methyl-β-alanine benzyl ester 
• 1345219-49-9 N-[1-(S)-benzyloxycarbonyl-3-phenylpropyl]-L-4,4'-biphenylalanyl-β-alanine benzyl ester 

Relevant articles and documents

A convenient method for the kinetic resolution of racemic 2-hydroxyalkanoates using diphenylacetic anhydride (DPHAA) and a chiral acyl-transfer catalyst

Diphenylacetic anhydride (DPHAA) was found to be a useful reagent for the kinetic resolution of racemic 2-hydroxyalkanoates in the presence of a catalytic amount of (R)-benzotetramisole ((R)-BTM). The combined use of DPHAA and (R)-BTM effectively produced a variety of the optically active 2-hydroxyalkanoates and the corresponding 2-acyloxyalkanoates from racemic 2-hydroxyalkanoates (s-values = 42-177). A fairly broad substrate scope was demonstrated by this novel chiral induction system. We also revealed that the use of only 0.3 equiv of DPHAA is enough to provide the optically active 2-acyloxyalkanoates in good yields and with excellent ee's by the added use of 0.3 equiv of pivalic anhydride for the kinetic resolution of the racemic 2-hydroxyalkanoates. Copyright

PROLINE ESTER AND PREPARATION CONTAINING THE SAME FOR PERCUTANEOUS ADMINISTRATION

A proline ester represented by the following formula (I) : wherein R1 represents a hydroxy-lower alkyl group, a lower alkoxy-lower alkyl group, or a lower alkoxy-lower alkoxy-lower alkyl group or a pharmaceutically acceptable salt thereof. The