1089280-36-3

Basic information

• Product Name: 8-[3-(methyloxy)-4-nitrophenyl]-1,4-dioxaspiro[4.5]dec-7-ene
• Synonyms: 8-[3-(methyloxy)-4-nitrophenyl]-1,4-dioxaspiro[4.5]dec-7-ene
• CAS NO: 1089280-36-3
• Molecular Weight: 291.304
• Mol File: 1089280-36-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 8-[3-(methyloxy)-4-nitrophenyl]-1,4-dioxaspiro[4.5]dec-7-ene(CAS DataBase Reference)
• NIST Chemistry Reference: 8-[3-(methyloxy)-4-nitrophenyl]-1,4-dioxaspiro[4.5]dec-7-ene(1089280-36-3)
• EPA Substance Registry System: 8-[3-(methyloxy)-4-nitrophenyl]-1,4-dioxaspiro[4.5]dec-7-ene(1089280-36-3)

Safety Data

• Hazardous Substances Data: 1089280-36-3(Hazardous Substances Data)

Upstream product

• 680596-79-6 4,4,5,5-tetramethyl-2-(1,4-dioxaspiro[4.5]dec-7-en-8-yl)-1,3,2-dioxaborolane 
• 103966-66-1 4-bromo-2-methoxy-1-nitro-benzene 
• 321-23-3 4-bromo-2-fluoronitrobenzene 
• 6627-53-8 1-chloro-3-methoxy-4-nitrobenzene 

Downstream Products

• 1089280-37-4 3'-methoxy-4'-nitro-2,5-dihydro-[1,1'-biphenyl]-4(3H)-one 

Relevant articles and documents

Anaplastic lymphoma kinase (ALK) inhibitor, and preparation method and application thereof

The invention relates to a compound as shown in a formula (I) which is described in the specification, and a pharmaceutical composition and a preparation method thereof. The compound can be used as anALK inhibitor for treatment of diseases mediated by ALK. The invention further relates to application of the compound as shown in the formula (I) and the pharmaceutical composition thereof to preparation of drugs used for treating diseases mediated by ALK.