109249-88-9

Basic information

• Product Name: 4,4′-diphenyl-[5,5′-bithiazole]-2,2′-diamine
• Synonyms: 4,4′-diphenyl-[5,5′-bithiazole]-2,2′-diamine
• CAS NO: 109249-88-9
• Molecular Weight: 350.468
• Mol File: 109249-88-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4,4′-diphenyl-[5,5′-bithiazole]-2,2′-diamine(CAS DataBase Reference)
• NIST Chemistry Reference: 4,4′-diphenyl-[5,5′-bithiazole]-2,2′-diamine(109249-88-9)
• EPA Substance Registry System: 4,4′-diphenyl-[5,5′-bithiazole]-2,2′-diamine(109249-88-9)

Safety Data

• Hazardous Substances Data: 109249-88-9(Hazardous Substances Data)

Upstream product

• 90043-56-4 C₁₈H₁₄O₃ 
• 102596-02-1 2-benzoyl-1,4-diphenylbut-2-ene-1,4-dione 
• 17356-08-0 thiourea 
• 142-46-1 bithiourea 
• 532-27-4 1-chloroacetophenone 
• 76187-15-0 4,4'-diphenyl-2,2'-diazane-1,2-diyl-bis-thiazole 
• 32147-16-3 meso-2,3-dibromo-1,4-diphenyl-1,4-butanedione 

Relevant articles and documents

Bronsted acid promoted addition-cyclization and C-C bond cleavage: A convenient synthesis of 2-amino-5-aroylmethylthiazoles derivatives

A Bronsted acid promoted C-C bond cleavage method for the synthesis of novel 2-amino-5-aroylmethylthiazole derivatives has been directly developed from 1,4-enediones and thioureas through self-sequenced thio-Michael-addition, intramolecular selective cyclization, dehydration/aromatization, and C-C bond cleavage reactions. It is noteworthy that this reaction has significant advantages in simple reagents, under environmentally benign conditions and with excellent yields. This highly efficient method is also a highly attractive alternative for the preparation of PLTP, CETP inhibitors and novel biheterocycles.