109545-84-8

Basic information

• Product Name: EverniMicin
• Synonyms: EverniMicin;56-deacetyl-57-demethyl-45-O-de(2-methyl-1-oxopropyl)-12-O-(2,3,6-trideoxy-3-C-methyl-4-O-methyl-3-nitro-alpha-L-arabino-hexopyranosyl)flambamycin 56-(2,4-dihydroxy-6-methylbenzoate);Everninomicin;Everninomicin 13384-1;Sch 27899
• CAS NO: 109545-84-8
• Molecular Formula: C₇₀H₉₇Cl₂NO₃₈
• Molecular Weight: 1631.40908
• Mol File: 109545-84-8.mol
• Article Data: 1

Chemical Properties

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Appearance: /
• Density: 1.55
• CAS DataBase Reference: EverniMicin(CAS DataBase Reference)
• NIST Chemistry Reference: EverniMicin(109545-84-8)
• EPA Substance Registry System: EverniMicin(109545-84-8)

Safety Data

• Hazardous Substances Data: 109545-84-8(Hazardous Substances Data)

Usage

Uses

ntibacterial.

Brand name

Ziracin (Schering-Plough HealthCare).

Downstream Products

• 104841-33-0 C₇₀H₉₉Cl₂NO₃₆ 
• 199486-49-2 C₇₀H₉₇Cl₂NO₃₈ 
• 98300-83-5 3,5-Dichloro-2,4-dimethoxy-6-methyl-benzoic acid (2R,3R,4R,6S)-6-((2R,3S,4R)-4-hydroxy-2-methyl-6-oxo-tetrahydro-pyran-3-yloxy)-4-((2S,4S,5R,6S)-5-methoxy-4,6-dimethyl-4-nitro-tetrahydro-pyran-2-yloxy)-2-methyl-tetrahydro-pyran-3-yl ester 
• 121256-50-6 C₄₃H₆₄O₂₅ 
• 226074-36-8 C₇₉H₁₀₉Cl₂NO₃₈ 
• 104841-33-0 C₇₀H₉₉Cl₂NO₃₆ 

Relevant articles and documents

Total synthesis of everninomicin 13,384-1 - Part 3: Synthesis of the DE fragment and completion of the total synthesis

The stereoselective construction of the DE fragment (2) of everninomicin 13,384-1 (1) is reported. From the two possible ways of inserting the DE fragment between the A1B(A)C and FGHA2 domains of the natural product, the sequence involving the DEFGHA2 segment was found to be the most viable. This coupling was followed by attachment of a suitably protected and activated A1B(A)C fragment which led, after orthoester construction and final deprotection to the targeted everninomicin 13,384-1 (1), completing the total synthesis of this complex naturally occurring substance.