199486-49-2Relevant articles and documents
Determination of the absolute stereochemistry at the C16 orthoester of everninomicin antibiotics; a novel acid-catalyzed isomerization of orthoesters
Ganguly, Ashit K.,McCormick, Jinping L.,Chan, Tze-Ming,Saksena, Anil K.,Das, Pradip R.
, p. 7989 - 7992 (1997)
The absolute stereochemistry at C16 orthoester center of Ziracin (1) was unequivocally established via a novel acid-catalyzed orthoester isomerization. Structures of the resulting isomers 2 and 3 were determined by chemical degradation and extensive spectroscopic analyses. This novel isomerization was successfully extended to other related everninomicins (11-13), thus completing the entire structural assignment of everninomicin antibiotics.
