1110711-01-7

Basic information

• Product Name: (11bS)-4,4-Dibutyl-4,5-dihydro-2,6-bis[3,5-bis(trifluoroMethyl)phenyl]-3H-dinaphtho[2,1-c:1′,2′-e]phosphepiniuM broMide
• Synonyms: (11bS)-4,4-Dibutyl-4,5-dihydro-2,6-bis[3,5-bis(trifluoroMethyl)phenyl]-3H-dinaphtho[2,1-c:1′,2′-e]phosphepiniuM broMide;(11bS)-(-)-4,4-Di-t-butyl-2,6-bis[3,5-bis(trifluoroMethyl)phenyl]-4,5-dihydro-3H-dinaphtho[2,1-c:1',2'-e]phosphepiniuM broMide, 99% S-MARUOKA CAT P-TB;(11bR)-(+)-4,4-Dibutyl-2,6-bis[3,5-bis(trifluoroMethyl)phenyl]-4,5-dihydro-3H-dinaphtho[2,1-c:1',2'-e]phosphepiniuM broMide, 99% R-MARUOKA CAT P-NB;(11bS)-4,4-Dibutyl-4,5-dihydro-2,6-bis[3,5-bis(trifluoromethyl)phenyl]-3H-dinaphtho[2,1-c:1',2'-e]phosphepinium bromide 95%;(11bR)-(+)-4,4-Dibutyl-2,6-bis[3,5-bis(trifluoromethyl)phenyl]-4,5-dihydro-3H-dinaphtho[2,1-c:1',2'-
• CAS NO: 1110711-01-7
• Molecular Formula: C46H40BrF12P
• Molecular Weight: 931.6683994
• Mol File: 1110711-01-7.mol
• Article Data: 3

Chemical Properties

• Melting Point: 262-263°C
• Appearance: /
• CAS DataBase Reference: (11bS)-4,4-Dibutyl-4,5-dihydro-2,6-bis[3,5-bis(trifluoroMethyl)phenyl]-3H-dinaphtho[2,1-c:1′,2′-e]phosphepiniuM broMide(CAS DataBase Reference)
• NIST Chemistry Reference: (11bS)-4,4-Dibutyl-4,5-dihydro-2,6-bis[3,5-bis(trifluoroMethyl)phenyl]-3H-dinaphtho[2,1-c:1′,2′-e]phosphepiniuM broMide(1110711-01-7)
• EPA Substance Registry System: (11bS)-4,4-Dibutyl-4,5-dihydro-2,6-bis[3,5-bis(trifluoroMethyl)phenyl]-3H-dinaphtho[2,1-c:1′,2′-e]phosphepiniuM broMide(1110711-01-7)

Safety Data

• WGK Germany: nwg
• Hazardous Substances Data: 1110711-01-7(Hazardous Substances Data)

Usage

Reaction

Chiral, phase-transfer catalyst for the asymmetric Michael and Mannich reactions of 3-aryloxindoles.

Upstream product

• 1732-72-5 di-n-butylphosphine 
• 109-65-9 1-bromo-butane 

Relevant articles and documents

Binaphthyl-modified quaternary phosphonium salts as chiral phase-transfer catalysts: Asymmetric amination of β-keto esters

(Chemical Equation Presented) A reliable phosphonium-based PTC: For the first time a chiral quaternary tetraalkylphosphonium salt has successfully been used as a phase-transfer catalyst (PTC) for asymmetric amination of β-keto esters, in high yield and with high ee (see scheme). Asymmetric amination of a cyclic five-membered β-keto ester is a valuable method for preparing a key intermediate for asymmetric synthesis of aldose reductase inhibitor AS-3201 (Ranirestat).

Efficient approach for the design of effective chiral quaternary phosphonium salts in asymmetric conjugate additions

An efficient approach for the design of chiral quaternary phosphonium bromides as chiral phase-transfer catalysts was demonstrated. A catalyst library of phosphonium salts with various structures was readily constructed using commercially available chiral phosphines as catalyst precursors, and an optimized catalyst was successfully applied to highly enantioselective conjugate additions under base-free phase-transfer conditions with low catalyst loading.