1132-38-3

Basic information

• Product Name: N-cyclohexylideneaniline
• CAS NO: 1132-38-3
• Molecular Formula: C₁₂H₁₅N
• Molecular Weight: 173.2542
• Mol File: 1132-38-3.mol
• Article Data: 42

Chemical Properties

• Boiling Point: 261.4°C at 760 mmHg
• Flash Point: 103.6°C
• Density: 0.99g/cm³
• Vapor Pressure: 0.0188mmHg at 25°C
• Refractive Index: 1.556
• CAS DataBase Reference: N-cyclohexylideneaniline(CAS DataBase Reference)
• NIST Chemistry Reference: N-cyclohexylideneaniline(1132-38-3)
• EPA Substance Registry System: N-cyclohexylideneaniline(1132-38-3)

Safety Data

• Hazardous Substances Data: 1132-38-3(Hazardous Substances Data)

Usage

General Description

N-cyclohexylideneaniline, also known as N-phenylcyclohexylidene, is a chemical compound with the molecular formula C13H15N. It is a substituted aniline with a cyclohexylidene group attached to the nitrogen atom. N-cyclohexylideneaniline is used as an intermediate in the synthesis of various organic compounds, particularly in the production of pharmaceuticals and agrochemicals. N-cyclohexylideneaniline is also employed as a building block for the preparation of dyes and pigments. It is a colorless to pale yellow liquid with a faint, amine-like odor, and it is considered to be a hazardous substance due to its toxic and irritating properties. Proper handling and storage precautions are necessary when working with this chemical.

Upstream product

• 64269-06-3 1-(phenylamino)cyclohexanecarbonitrile 
• 108-94-1 cyclohexanone 
• 62-53-3 aniline 
• 1670-47-9 1,1-diethoxycyclohexane 
• 622-37-7 Phenyl azide 
• 110-83-8 cyclohexene 
• 622-44-6 phenylcarbonimidic dichloride 
• 23708-48-7 pentamethylenebis(magnesium bromide) 
• 67-66-3 chloroform 
• 104-88-1 4-chlorobenzaldehyde 
• 100-52-7 benzaldehyde 
• 2720-41-4 cyclohexanethione 
• 100-64-1 cyclohexanone-oxime 
• 108-93-0 cyclohexanol 

Downstream Products

• 17294-88-1 2-phenyl-1-oxa-2-azaspiro<2,5>hexane 
• 1821-36-9 N-phenyl-2-cyclohexylamine 
• 80254-41-7 1,3-diphenyl-5,6,7,8-tetrahydro-1H-quinazoline-2,4-dithione 
• 38425-88-6 3-(2-phenylimino-cyclohexyl)-propionitrile 
• 57178-09-3 4?phenyl?1?thia?4?azaspiro[4.5]decan?3?one 
• 38765-32-1 1-phenyl-4,5,6,7-tetrahydro-1H-benzo[c]isothiazole-3-thione 
• 33542-30-2 N-1-cyclohexenyl-N-phenylcarbamyl chloride 
• 69139-51-1 4-(1'-oxo-2'-phenyl-1',4'-dihydro-2'H-spiro[cyclohexane-1,3'-isoquinoline]-4'-carbonyl)-morpholine 
• 93994-44-6 N-Phenyl-N'-(4-chlor-benzolsulfonyl)-C-cyclopentyl-formamidin 
• 5785-79-5 (C₃H₇)2BN(C₆H₅)C₆H₉ 
• 412342-35-9 5-phenyl-1-oxa-5-aza-spiro[5.5]undecane-2,4-dione 
• 59631-53-7 2-Isopropyl-3,3-dimethyl-thiobutyranilid 
• 30432-66-7 N-ethyl-N-cyclohex-1-enyl-aniline 
• 2720-41-4 cyclohexanethione 

Relevant articles and documents

-

-

A facile synthesis of γ-lactams and secondary amines from conjugated dienes and imines

-

The azaallylic anion as a synthon for Pd-catalyzed synthesis of heterocycles: domino two- and three-component synthesis of indoles

(Chemical Equation Presented) Piecing it all together with palladium: Two- and three-component cascade processes that are promoted by a multifunctional Pd catalyst lead to indoles in a highly efficient manner (see scheme). The key step is the Pd-catalyzed α-arylation of imines with o-dihalobenzene derivatives.

Sulfated polyborate: A dual catalyst for the reductive amination of aldehydes and ketones by NaBH4

An efficient, quick, and environment-friendly one-pot reductive amination of aldehydes or ketones was developed. In ethanol at 70 °C, a imination catalyzed by sulfated polyborate and further reduced by sodium borohydride yields various amines. The present method has many significant benefits, including a shorter reaction time, excellent yields, and a hassle-free, straightforward experimental process. The reaction has a wide range of applications due to its flexibility, including secondary amine for reductive amination.

Reductive amination of ketones/aldehydes with amines using BH3N(C2H5)3as a reductant

Herein, we report the first example of efficient reductive amination of ketones/aldehydes with amines using BH3N(C2H5)3 as a catalyst and a reductant under mild conditions, affording various tertiary and secondary amines in excellent yields. A mechanistic study indicates that BH3N(C2H5)3 plays a dual function role of promoting imine and iminium formation and serving as a reductant in reductive amination. This journal is

Colloidal and Nanosized Catalysts in Organic Synthesis: XXIII. Reductive Amination of Carbonyl Compounds Catalyzed by Nickel Nanoparticles in a Plug-Flow Reactor

Reductive amination of aldehydes and ketones with primary and secondary amines under catalysis with nickel nanoparticles supported on zeolite X, MgO, or activated carbon in the gas phase or in the gas-liquid system in a plug-flow reactor proceeds at atmospheric pressure of hydrogen with the formation of secondary or tertiary amines in high yield.