113934-27-3

Basic information

• Product Name: 1-(4-CHLOROPHENYL)-1H-1,2,3-TRIAZOLE-4-CARBALDEHYDE
• Synonyms: 1-(4-CHLOROPHENYL)-1H-1,2,3-TRIAZOLE-4-CARBALDEHYDE
• CAS NO: 113934-27-3
• Molecular Formula: C₉H₆ClN₃O
• Molecular Weight: 207.62
• Mol File: 113934-27-3.mol
• Article Data: 30

Chemical Properties

• Melting Point: 151-153°
• Boiling Point: 383.8±48.0 °C(Predicted)
• Appearance: /
• Density: 1.41±0.1 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: -1.42±0.70(Predicted)
• CAS DataBase Reference: 1-(4-CHLOROPHENYL)-1H-1,2,3-TRIAZOLE-4-CARBALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-CHLOROPHENYL)-1H-1,2,3-TRIAZOLE-4-CARBALDEHYDE(113934-27-3)
• EPA Substance Registry System: 1-(4-CHLOROPHENYL)-1H-1,2,3-TRIAZOLE-4-CARBALDEHYDE(113934-27-3)

Safety Data

• Hazard Codes: Xi
• Statements: 43
• Safety Statements: 36/37
• HazardClass: IRRITANT
• Hazardous Substances Data: 113934-27-3(Hazardous Substances Data)

Usage

Description

1-(4-CHLOROPHENYL)-1H-1,2,3-TRIAZOLE-4-CARBALDEHYDE is an organic compound with the chemical structure featuring a triazole ring and a chlorophenyl group. It is known for its potential applications in various fields due to its unique chemical properties.

Uses

Used in Pharmaceutical Industry:
1-(4-CHLOROPHENYL)-1H-1,2,3-TRIAZOLE-4-CARBALDEHYDE is used as a reactant for the preparation of N-phenyl-1,2,3-triazole derivatives, which exhibit antitubercular activity. The compound plays a crucial role in the development of new antitubercular drugs, targeting the treatment and prevention of tuberculosis.

Upstream product

• 133902-66-6 1‐(4‐chlorophenyl)‐1H‐1,2,3‐triazole‐4‐yl‐methanol 
• 50704-41-1 2-diazo-malonaldehyde 
• 106-47-8 4-chloro-aniline 
• 20265-96-7 p-chloroaniline hydrochloride 
• 3296-05-7 1-azido-4-chlorobenzene 
• 133902-65-5 ethyl 1-(4-chlorophenyl)-1H-1,2,3-triazole-4-carboxylate 
• 107-19-7 propargyl alcohol 
• 16681-68-8 1H-1,2,3-triazole-4⁽⁵⁾-carbaldehyde 
• 352-33-0 1-Chloro-4-fluorobenzene 

Downstream Products

• 133902-62-2 [1-[1-(4-Chloro-phenyl)-1H-[1,2,3]triazol-4-yl]-meth-(E)-ylidene]-phenyl-amine 
• 578703-91-0 methyl 1-(4-chlorophenyl)-1H-1,2,3-triazole-4-carboxylate 
• 578703-73-8 1-(4-chlorophenyl)-1H-1,2,3-triazole-4-carbohydrazide 
• 133902-50-8 (4-Chloro-phenyl)-[1-(1-phenyl-1H-[1,2,3]triazol-4-yl)-meth-(E)-ylidene]-amine 
• 1224470-74-9 1-(4-hydroxyphenyl)-4-{[1-(4-chlorophenyl)-1H-1,2,3-triazol-4-yl]methyl}piperazine 
• 1325725-19-6 1-(4-chlorophenyl)-4-vinyl-1H-1,2,3-triazole 
• 1578191-17-9 (E)-1-(4-chlorophenyl)-4-((2-Phenylhydrazono)methyl)-1H-1,2,3-triazole 
• 1578191-18-0 (E)-4-((2-(4-bromophenyl)hydrazono)methyl)-1-(4-chlorophenyl)-1H-1,2,3-triazole 
• 1578191-20-4 (E)-1-(4-chlorophenyl)-1H-1,2,3-triazole-4-carbaldehyde oxime 
• 1274943-22-4 N-((1-(4-chlorophenyl)-1H-1,2,3-triazol-4-yl)methyl)aniline 
• 1613039-70-5 N-((1-(4-chlorophenyl)-1H-1,2,3-triazol-4-yl)methylene)aniline oxide 
• 1613039-90-9 N-((1-(4-chlorophenyl)-1H-1,2,3-triazol-4-yl)methylene)aniline 

Relevant articles and documents

Design, synthesis and biological evaluation of novel benzimidazole amidines as potent multi-target inhibitors for the treatment of non-small cell lung cancer

A series of novel amidino 2-substituted benzimidazoles linked to 1,4-disubstituted 1,2,3-triazoles were synthesized by implementation of microwave and ultrasound irradiation in click reaction and subsequent condensation of thus obtained 4-(1,2,3-triazol-1

Selective CDK4/6 inhibition of novel 1,2,3-triazole tethered acridinedione derivatives induces G1/S cell cycle transition arrest via Rb phosphorylation blockade in breast cancer models

CDK4 & CDK6 are essential regulators of initial cell cycle phases and are always considered an exciting choice for anti-cancer therapy. In the present study, we presented the structure-based rational design & synthesis of a new class of 1,2,3-triazole tet

[Et3NH][HSO4] catalyzed solvent-free synthesis of new 1,2,3-triazolidene-indolinone derivatives

A series of new 1,2,3-triazolidene-indolinone derivatives (17a-j) were designed and synthesized via [Et3NH] [HSO4] catalyzed solvent-free approach. The synthesis strongly relied on Knoevenagel condensation of 1,4-disubstituted 1,2,3-