133902-66-6

Basic information

• Product Name: [1-(4-Chlorophenyl)-1H-1,2,3-triazol-4-yl]methanol
• Synonyms: [1-(4-CHLOROPHENYL)-1H-1,2,3-TRIAZOL-4-YL]METHANOL;[1-(4-chlorophenyl)-1H-1,2,3-t;1-(4-Chlorophenyl)-1H-1,2,3-Tr;1-(4-CHLOROPHENYL)-1H-1,2,3-TRIAZOL-4-YL]METHANO;1-(4-Chlorophenyl)-1H-1,2,3-triazole-4-methanol
• CAS NO: 133902-66-6
• Molecular Formula: C₉H₈ClN₃O
• Molecular Weight: 209.63
• Product Categories: API intermediates;Pyrrodiazole
• Mol File: 133902-66-6.mol
• Article Data: 37

Chemical Properties

• Melting Point: 147-149°C
• Boiling Point: 402.933 °C at 760 mmHg
• Flash Point: 197.487 °C
• Appearance: /Solid
• Density: 1.424 g/cm³
• Vapor Pressure: 3.24E-07mmHg at 25°C
• Refractive Index: 1.661
• PKA: 12.89±0.10(Predicted)
• CAS DataBase Reference: [1-(4-Chlorophenyl)-1H-1,2,3-triazol-4-yl]methanol(CAS DataBase Reference)
• NIST Chemistry Reference: [1-(4-Chlorophenyl)-1H-1,2,3-triazol-4-yl]methanol(133902-66-6)
• EPA Substance Registry System: [1-(4-Chlorophenyl)-1H-1,2,3-triazol-4-yl]methanol(133902-66-6)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 133902-66-6(Hazardous Substances Data)

Usage

General Description

"[1-(4-Chlorophenyl)-1H-1,2,3-triazol-4-yl]methanol" is a specialized chemical compound that belongs to the group of 1,2,3-triazoles. 1,2,3-triazole structures are often found in pharmaceutical compounds due to their versatile biological activities. The prefix "1-(4-Chlorophenyl)" in the chemical's name indicates the presence of a chlorophenyl group attached to the 1-position of the triazole ring. On the other side, the "4-yl]methanol" indicates a methanol group attached to the 4-position. The exact attributes, reactivity, and applications of this chemical can vary widely depending on the broader context of its use, however, it generally possesses both the typical reactivity of a 1,2,3-triazole, and the typical properties associated with a chlorophenyl group and a methanol group.

InChI:InChI=1/C9H8ClN3O/c10-7-1-3-9(4-2-7)13-5-8(6-14)11-12-13/h1-5,14H,6H2

Upstream product

• 133902-65-5 ethyl 1-(4-chlorophenyl)-1H-1,2,3-triazole-4-carboxylate 
• 3296-05-7 1-azido-4-chlorobenzene 
• 107-19-7 propargyl alcohol 
• 106-47-8 4-chloro-aniline 

Downstream Products

• 113934-27-3 1-(4-chlorophenyl)-1H-1,2,3-triazole-4-carbaldehyde 
• 133902-50-8 (4-Chloro-phenyl)-[1-(1-phenyl-1H-[1,2,3]triazol-4-yl)-meth-(E)-ylidene]-amine 
• 133902-62-2 [1-[1-(4-Chloro-phenyl)-1H-[1,2,3]triazol-4-yl]-meth-(E)-ylidene]-phenyl-amine 
• 1325725-11-8 1-(4-chlorophenyl)-4-(fluoromethyl)-1H-1,2,3-triazole 
• 1325725-19-6 1-(4-chlorophenyl)-4-vinyl-1H-1,2,3-triazole 
• 1333225-99-2 1-{3-[(1-(4-chlorophenyl)-1H-[1,2,3]triazol-4-yl)methoxy]-2-hydroxypropyl}-2-hydroxymethyl-piperidine-3,4,5-triol 
• 1333226-01-9 C₁₂H₁₂ClN₃O₂ 
• 1578191-17-9 (E)-1-(4-chlorophenyl)-4-((2-Phenylhydrazono)methyl)-1H-1,2,3-triazole 
• 1578191-18-0 (E)-4-((2-(4-bromophenyl)hydrazono)methyl)-1-(4-chlorophenyl)-1H-1,2,3-triazole 
• 1578191-20-4 (E)-1-(4-chlorophenyl)-1H-1,2,3-triazole-4-carbaldehyde oxime 
• 338419-16-2 (1-(4-chlorophenyl)-1H-1,2,3-triazole-4-yl)methyl benzoate 
• 1578190-81-4 (1-(4-chlorophenyl)-1H-1,2,3-triazole-4-yl)methyl hexanoate 
• 1578190-85-8 (1-(4-chlorophenyl)-1H-1,2,3-triazole-4-yl)methyl decanoate 
• 1578190-90-5 1-(4-chlorophenyl)-4-(ethoxymethyl)-1H-1,2,3-triazole 

Relevant articles and documents

Anti-Lung Cancer Activities of 1,2,3-Triazole Curcumin Derivatives via Regulation of the MAPK/NF-κB/STAT3 Signaling Pathways

In this study, a series of curcumin derivatives containing 1,2,3-triazole were designed and synthesized, and their inhibitory activities against the proliferation of lung cancer cells were studied. Compound 5 k (3,4-dichlorobenzyltriazole methyl curcumin)

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[Et3NH][HSO4] catalyzed solvent-free synthesis of new 1,2,3-triazolidene-indolinone derivatives

A series of new 1,2,3-triazolidene-indolinone derivatives (17a-j) were designed and synthesized via [Et3NH] [HSO4] catalyzed solvent-free approach. The synthesis strongly relied on Knoevenagel condensation of 1,4-disubstituted 1,2,3-