115622-65-6Relevant articles and documents
Cephalosporin 3'-Quinolone Esters with a Dual Mode of Action
Albrecht, Harry A.,Beskid, George,Chan, Ka-Kong,Christenson, James G.,Cleeland, Roy,et al.
, p. 77 - 86 (2007/10/02)
According to the generally accepted mechanism by which bacterial enzymes react with cephalosporins, opening of the β-lactam ring can lead to the expulsion of a 3'-substituent.A series of dual-action cephalosporins was prepared in which antibacterial quino