117782-95-3 Usage
Description
11β-hydroxy-16α,17α-<(1-methylethylidene)bis(oxy)>-3-oxoandrosta-1,4-diene is a non-fluorinated steroid anti-inflammatory drug and a degradation product of desonide (D296940).
Uses
Used in Pharmaceutical Industry:
11β-hydroxy-16α,17α-<(1-methylethylidene)bis(oxy)>-3-oxoandrosta-1,4-diene is used as an anti-inflammatory agent for its ability to reduce inflammation and alleviate pain associated with various conditions. Its steroidal structure allows it to effectively target and modulate the immune response, making it a valuable treatment option for inflammatory disorders.
Check Digit Verification of cas no
The CAS Registry Mumber 117782-95-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,7,7,8 and 2 respectively; the second part has 2 digits, 9 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 117782-95:
(8*1)+(7*1)+(6*7)+(5*7)+(4*8)+(3*2)+(2*9)+(1*5)=153
153 % 10 = 3
So 117782-95-3 is a valid CAS Registry Number.
117782-95-3Relevant articles and documents
Photochemistry of desonide, a non-fluorinated steroidal anti-inflammatory drug
Iqbal, Jawaid,Husain, Adil,Gupta, Anamika
, p. 836 - 838 (2007/10/03)
The photochemistry of anti-inflammatory drug desonide (De, 1) was studied in aerobic as well as in anaerobic condition with different irradiation wavelengths (254, 310 nm) in acetonitrile and 2-propanol. All photoproducts obtained were isolated and characterized on the basis of IR, 1H-, 13C-NMR spectroscopy and elemental analysis study. The products were: 11β,21-dihydroxy-16α,17α-(1-methylethylidenedioxy)-1,5- cyclopregn-3-ene-2,20-dione 2 (254 nm), 11β-hydroxy-16α,17α-(1- methylethylidenedioxy)androsta-1,4-diene-3-one 3 (310 nm/2-propanol), 17β-hydroperoxy-11β-hydroxy-16α,17α-(1- methylethylidenedioxy)androsta-1,4-diene-3-one 4 (310 nm/O2/2- propanol). Cyclohexadienone moiety in ring A and keto group at C17 were found to be deeply modified by UV light therefore, loss of biological activity both during storage and in vivo can not be ruled out.
