1187020-64-9Relevant articles and documents
Synthesis of new 1,4-dihydropyridine derivatives containing thiazolyl substituents
Bazargan, Leila,Shafiee, Abbas,Amini, Mohsen,Dezfouli, Ebrahim Bakhshi,Azizi, Ebrahim,Ghaffari, Seyed Mahmood
experimental part, p. 602 - 609 (2009/10/02)
A series of 4-[2-methyl (or aryl) thiazole-4-yl]-2,6-dimethyl-3,5-diacetyl (or dibenzoyl) 1,4-dihydropyridines were synthesized using a modified Hantzsch reaction involving the condensation of the corresponding aldehyde with acetyl acetone or benzoyl acetone. The preparation of the corresponding aldehydes (2-methylthiazole-4-carboxaldehyde and some 2-arylthiazole-4-carboxaldehydes) was achieved by a simplified protocol of the published synthesis.