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1214370-77-0

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1214370-77-0 Usage

General Description

3-Amino-5-(trifluoromethyl)pyridine-2-carboxylic acid is a chemical compound that belongs to the pyridine carboxylic acids class. It is a derivative of pyridine and contains an amino group and a carboxylic acid group, as well as a trifluoromethyl substituent. 3-Amino-5-(trifluoromethyl)pyridine-2-carboxylic acid is used in the pharmaceutical industry as a building block for the synthesis of various drug molecules. It has potential applications in the development of new drugs for the treatment of various diseases, including cancer and inflammatory conditions. Additionally, its unique structure and properties make it a valuable tool for organic synthesis and medicinal chemistry research.

Check Digit Verification of cas no

The CAS Registry Mumber 1214370-77-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,1,4,3,7 and 0 respectively; the second part has 2 digits, 7 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1214370-77:
(9*1)+(8*2)+(7*1)+(6*4)+(5*3)+(4*7)+(3*0)+(2*7)+(1*7)=120
120 % 10 = 0
So 1214370-77-0 is a valid CAS Registry Number.

1214370-77-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 3-amino-5-(trifluoromethyl)pyridine-2-carboxylic acid

1.2 Other means of identification

Product number -
Other names 3-Amino-5-trifluoromethyl-pyridine-2-carboxylic acid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1214370-77-0 SDS

1214370-77-0Downstream Products

1214370-77-0Relevant articles and documents

Discovery of Icenticaftor (QBW251), a Cystic Fibrosis Transmembrane Conductance Regulator Potentiator with Clinical Efficacy in Cystic Fibrosis and Chronic Obstructive Pulmonary Disease

Grand, Darren Le,Gosling, Martin,Baettig, Urs,Bahra, Parmjit,Bala, Kamlesh,Brocklehurst, Cara,Budd, Emma,Butler, Rebecca,Cheung, Atwood K.,Choudhury, Hedaythul,Collingwood, Stephen P.,Cox, Brian,Danahay, Henry,Edwards, Lee,Everatt, Brian,Glaenzel, Ulrike,Glotin, Anne-Lise,Groot-Kormelink, Paul,Hall, Edward,Hatto, Julia,Howsham, Catherine,Hughes, Glyn,King, Anna,Koehler, Julia,Kulkarni, Swarupa,Lightfoot, Megan,Nicholls, Ian,Page, Christopher,Pergl-Wilson, Giles,Popa, Mariana Oana,Robinson, Richard,Rowlands, David,Sharp, Tom,Spendiff, Matthew,Stanley, Emily,Steward, Oliver,Taylor, Roger J.,Tranter, Pamela,Wagner, Trixie,Watson, Hazel,Williams, Gareth,Wright, Penny,Young, Alice,Sandham, David A.

, p. 7241 - 7260 (2021/06/28)

Mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) ion channel are established as the primary causative factor in the devastating lung disease cystic fibrosis (CF). More recently, cigarette smoke exposure has been shown to be asso

Pyridine and Pyrazine derivative for the Treatment of CF

-

, (2011/10/10)

The present invention provides pyridine and pyrazine derivatives which restore or enhance the function of mutant and/or wild type CFTR to treat cystic fibrosis, primary ciliary dyskinesia, chronic bronchitis, chronic obstructive pulmonary disease, asthma, respiratory tract infections, lung carcinoma, xerostomia and keratoconjunctivitis sire, or constipation (IBS, IBD, opioid induced). Pharmaceutical compositions comprising such derivatives are also encompassed.

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