1239864-83-5

Basic information

• Product Name: 1-methyl-4-(phenyl-sulfonyl)-1H-furo[3,4-b]indol-3(4H)-one
• Synonyms: 1-methyl-4-(phenyl-sulfonyl)-1H-furo[3,4-b]indol-3(4H)-one
• CAS NO: 1239864-83-5
• Molecular Weight: 327.361
• Mol File: 1239864-83-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-methyl-4-(phenyl-sulfonyl)-1H-furo[3,4-b]indol-3(4H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-methyl-4-(phenyl-sulfonyl)-1H-furo[3,4-b]indol-3(4H)-one(1239864-83-5)
• EPA Substance Registry System: 1-methyl-4-(phenyl-sulfonyl)-1H-furo[3,4-b]indol-3(4H)-one(1239864-83-5)

Safety Data

• Hazardous Substances Data: 1239864-83-5(Hazardous Substances Data)

Upstream product

• 342405-28-1 1-phenylsulfonyl-1H-2-indolecarboxylic acid chloride 
• 60376-48-9 methyl 1-(phenylsulfonyl)-1H-indole-2-carboxylate 
• 98-09-9 benzenesulfonyl chloride 
• 40899-93-2 1-(phenylsulfonyl)-1H-indole-2-carboxylic acid 
• 1202-04-6 indole-2-carboxylic acid methyl ester 
• 1239864-88-0 N-benzenesulfonyl-2-(N',N'-dimethylhydrazinecarbonyl)indole 
• 1352536-81-2 C₁₉H₂₁N₃O₄S 
• 1477-50-5 Indole-2-carboxylic acid 

Downstream Products

• 89241-38-3 1,3-dimethyl-4-(phenylsulfonyl)-4H-furo[3,4-b]indole 

Relevant articles and documents

A convenient access to 1,3-disubstituted furo[3,4-b]indoles by acid ion-exchange resin-catalyzed furan formation

Efficient synthesis of furo[3,4-b]indoles starting from the corresponding indole is reported. The first route involves derivatization, protection, and deprotection steps, which stretch the syntheses. The second method provides a shorter and more efficient strategy to accessing the furoindole. The innovation starts with alkylation at C-2 of the indole presenting at the C-3 position a ketone-acetal, followed by the cycloaromatization catalyzed by polymeric ion-exchange resins. The second route represents a significant improvement over other methods previously described.