1253522-98-3

Basic information

• Product Name: 1-benzyl-3-bromo-5-(1-methyl-5-oxopyrrolidin-2-yl)pyridin-1-ium trifluoromethanesulfonate
• Synonyms: 1-benzyl-3-bromo-5-(1-methyl-5-oxopyrrolidin-2-yl)pyridin-1-ium trifluoromethanesulfonate
• CAS NO: 1253522-98-3
• Molecular Weight: 495.317
• Mol File: 1253522-98-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-benzyl-3-bromo-5-(1-methyl-5-oxopyrrolidin-2-yl)pyridin-1-ium trifluoromethanesulfonate(CAS DataBase Reference)
• NIST Chemistry Reference: 1-benzyl-3-bromo-5-(1-methyl-5-oxopyrrolidin-2-yl)pyridin-1-ium trifluoromethanesulfonate(1253522-98-3)
• EPA Substance Registry System: 1-benzyl-3-bromo-5-(1-methyl-5-oxopyrrolidin-2-yl)pyridin-1-ium trifluoromethanesulfonate(1253522-98-3)

Safety Data

• Hazardous Substances Data: 1253522-98-3(Hazardous Substances Data)

Upstream product

• 41194-00-7 5-Hydroxy-N-methyl-2-pyrrolidone 
• 54010-75-2 zinc trifluoromethanesulfonate 

Relevant articles and documents

One-pot formation of piperidine- and pyrrolidine-substituted pyridinium salts via addition of 5-alkylaminopenta-2,4-dienals to N-acyliminium ions: Application to the synthesis of (±)-nicotine and analogs

Addition of 5-alkylaminopenta-2,4-dienals onto N-acyliminium ions, generated in situ from α-hydroxycarbamates derived from pyrrolidine or piperidine, in the presence of zinc triflate, followed by dehydrative cyclization, allowed the formation of pyridinium salts substituted at their 3-position by a five- or six-membered nitrogen heterocycle. Subsequent N-dealkylation of the pyridinium moiety and deprotection of the secondary amine or reduction of the carbamate function led to (±)-nicotine and analogs.