41194-00-7Relevant articles and documents
Construction of Functionalized Azapolycyclic Architectures via Formal Amide Insertion at a Low Catalyst Loading of Copper Trifluoroacetylacetonate
Harada, Shingo,Kato, Ryosuke,Nemoto, Tetsuhiro
, p. 3123 - 3129 (2016)
A formal amide insertion reaction for the synthesis of nitrogen-bridged polycyclic frameworks with diverse functionalities was developed using a sustainable copper catalyst as an advantageous alternative to precious rhodium catalysts. The remarkable feature of this methodology is the amount of catalyst loading (0.05 mol%). The optimized reaction conditions enable access to aromatic ring-fused 8-azabicyclo[3.2.1]octane, 9-azabicyclo[3.3.1]nonane, and 6-azabicyclo[3.2.2]nonane derivatives in moderate to excellent yields. (Figure presented.).
One-pot synthesis of pyrrolidino- and piperidinoquinolinones by three-component aza-Diels-Alder reactions of in situ generated N-arylimines and cyclic enamides
Zhang, Wei,Zhang, Wenxue,Dai, Yisi,Wang, Xuerui
supporting information; experimental part, p. 6122 - 6126 (2011/12/01)
An efficient synthesis of hexahydropyrrolo[3,2-c]quinolin-2-ones and hexahydropyridino[3,2-c]quinolin-2-ones has been developed in moderate to high yields by one-pot two-step aza-Diels-Alder reactions of N-arylimines, formed in situ from anilines and benz
The photooxidative degradation of N-methylpyrrolidinone in the presence of Cs3PW12O40 and TiO2 colloid photocatalysts
Friesen, Duane A.,Headley, John V.,Langford, Cooper H.
, p. 3193 - 3198 (2007/10/03)
The mechanisms of the heterogeneous photocatalytic behavior of TiO2 and Cs3PW12O40 for the oxidative destruction of N-methylpyrrolidinone (NMP) in water are discussed. Both photocatalysts generate H-methylsuccinimide (NMS) and succinimide as the main intermediates from oxidation at the α-carbon and methyl positions. 2-Pyrrolidmone (2P) and 5-hydroxy-N-methylpyrrolidinone (5-HNMP) have also been identified as primary intermediates These intermediates are all broken down under further photooxidation. However, differences in product distribution indicate the possibility of several mechanistic pathways. Hydroxyl radical-like attack predominates for TiO2- photocatalyzed degradation, whereas the polyoxotungstate appears to oxidatrvely destroy NMP by both OH radical attack and direct oxidation For TiO2, the relative quantum yields for NMP oxidation (0.5 g L-1 TiO2, pH 3. 254 nm, 7 × 10-6 ein sec-1) increase from 3PW12O40 under the same conditions, the apparent quantum yield is nearly invariant (0.005-0.009) over the concentration range 10- 1000 ppm.
