125796-46-5Relevant articles and documents
Iron-catalyzed regioselective alkylation of 1,4-quinones and coumarins with functionalized alkyl bromides
Li, Dengke,Shen, Xianfu
supporting information, p. 750 - 754 (2020/02/11)
A simple and efficient Fe-catalyzed regioselective alkylation of 1,4-quinones and coumarins, using functionalized alkyl bromides as alkylating reagents, has been developed. The reaction proceeds under mild conditions with the addition of alkyl bromides to a wide range of 1,4-quinone and coumarin derivatives with a broad substrate scope and wide functional group tolerance to provide the products in good yields. Further application of these strategies could be extended to important biologically active antimalarial lead drugs, such as plasmodione on a gram scale in a single step for medicinal purposes.
Synthesis of 3-benzylcoumarins using suzuki coupling reaction
Kwon, Young Bum,Park, Jinhyung,Choi, Bo Ram,Kim, Hyun Soo,Yoon, Cheol Min
, p. 2897 - 2898 (2016/02/23)
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A CONVINIENT SYNTHESIS OF 3-BENZYL-4-SUBSTITUTED COUMARINS AND THEIR BENZO DERIVATIVES
Britto, Nirmala,Gore, Vinayak G.,Mali, R. S.,Ranade, A. C.
, p. 1899 - 1910 (2007/10/02)
It is reported in the literature that alkylation of simple (unsubstituted) phosphorane with alkyl halide in ethyl acetate leads to equimolar mixture of alkylated phosphorane and salt of the unsubstituted phosphorane.Here we report exclusive formation of a
