127934-39-8

Basic information

• Product Name: 4-methyl-1,2,3,4-tetrahydrospiro
• Synonyms: 4-methyl-1,2,3,4-tetrahydrospiro
• CAS NO: 127934-39-8
• Molecular Weight: 215.338
• Mol File: 127934-39-8.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 4-methyl-1,2,3,4-tetrahydrospiro(CAS DataBase Reference)
• NIST Chemistry Reference: 4-methyl-1,2,3,4-tetrahydrospiro(127934-39-8)
• EPA Substance Registry System: 4-methyl-1,2,3,4-tetrahydrospiro(127934-39-8)

Safety Data

• Hazardous Substances Data: 127934-39-8(Hazardous Substances Data)

Upstream product

• 153397-15-0 N-α-chloroacetyl-3,4-dihydro-4-methylspiro 
• 153397-16-1 1,2,3,4-tetrahydro-4-methyl-1-(α-bromopropionyl)spiro 
• 1132-38-3 N-cyclohexylidenebenzenamine 
• 705269-17-6 N-(1-allylcyclohexyl)-N-(2'-benzylphenyl)amine 
• 139010-17-6 N-acetyl-1,2,3,4-tetrahydro-4-methyl-1-acetylspiro 
• 127934-37-6 1-allyl-1-phenylaminocyclohexane 
• 844440-56-8 (2-benzyl-phenyl)-cyclohexylidene-amine 
• 108-94-1 cyclohexanone 
• 28059-64-5 2-benzylaniline 

Relevant articles and documents

SYNTHESIS OF SPIRO ANALOGS OF LILOLIDINE ALKALOIDS

The Friedel-Krafts intramolecular cyclization of N-chloroacetyl- and N-α-bromopropionyl-4-methylspiro was used to obtain 2-oxo-1,2,5,6-tetrahydro-4H-spiro - spiro analogs of lilolidine alkaloids.

SYNTHESIS OF N-ALKYL(ACYL)-1,2,3,4-TETRAHYDRO-4-METHYLSPIRO AND THEIR CONVERSIONS

The alkylation and acylation of 1,2,3,4-tetrahydro-4-methylspiro and its bromo(methyl) derivatives substituted in the benzene ring, as well as 1,2,3,4-tetrahydro-4-methylspiro, were studied.It was established that the N-allyl derivatives of spiro are converted to their 8-allyl-substituted analogs by the action of sulfuric acid, boron trifluoride etherate, and aluminum chloride.It was shown that the N-acyl-substituted spiro are recyclized to spiro in phosphoric acid.