1281973-56-5Relevant articles and documents
New glucocerebrosidase inhibitors by exploration of chemical diversity of N -substituted aminocyclitols using click chemistry and in situ screening
Díaz, Lucía,Casas, Josefina,Bujons, Jordi,Llebaria, Amadeu,Delgado, Antonio
, p. 2069 - 2079 (2011/06/10)
A library of aminocyclitols derived from CuAAC reaction between N-propargylaminocyclitol 4 and a series of azides [1′25] is described and tested against GCase. Azides have been chosen from a large collection of potential candidates that has been filtered