128252-48-2

Basic information

• Product Name: L-Proline, 1-[[(phenylmethoxy)amino]carbonyl]-, methyl ester
• CAS NO: 128252-48-2
• Molecular Formula: C14H18N2O4
• Molecular Weight: 278.308
• Mol File: 128252-48-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: L-Proline, 1-[[(phenylmethoxy)amino]carbonyl]-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: L-Proline, 1-[[(phenylmethoxy)amino]carbonyl]-, methyl ester(128252-48-2)
• EPA Substance Registry System: L-Proline, 1-[[(phenylmethoxy)amino]carbonyl]-, methyl ester(128252-48-2)

Safety Data

• Hazardous Substances Data: 128252-48-2(Hazardous Substances Data)

Upstream product

• 622-33-3 N-benzyloxyamine 
• 85665-59-4 (S)-methyl 1-(chlorocarbonyl)pyrrolidine-2-carboxylate 

Downstream Products

• 140160-62-9 (5S)-3-(benzyloxy)-1,3-diazabicyclo<3.3.0>octane-2,4-dione 
• 140160-63-0 (5S)-3-hydroxy-1,3-diazabicyclo<3.3.0>octane-2,4-dione 

Relevant articles and documents

Asymmetric Diels-Alder Cycloadditions with Chiral Carbamoyl Dienophiles

Chiral acylnitroso dienophiles 14, which were obtained from L-proline and from D-mandelic acid, reacted with cyclohexa-1,3-diene to give the expected diastereoisomers 15 and 16 (Scheme 2 and Table 1).The d.e. values for these Diels-Alder reactions were moderate; they are related to the molecular stiffness of the dienophiles.The absolute configuration of the major cycloadducts was interpreted in terms of HOMO/LUMO interactions, the approach being 'endo' and the acylnitroso dienophiles reacting from their s-cis-conformation.