1304081-27-3

Basic information

• Product Name: 5-(azidomethyl)-3-(4-methoxyphenyl)-1,2,4-oxadiazole
• Synonyms: 5-(azidomethyl)-3-(4-methoxyphenyl)-1,2,4-oxadiazole
• CAS NO: 1304081-27-3
• Molecular Weight: 231.214
• Mol File: 1304081-27-3.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 5-(azidomethyl)-3-(4-methoxyphenyl)-1,2,4-oxadiazole(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(azidomethyl)-3-(4-methoxyphenyl)-1,2,4-oxadiazole(1304081-27-3)
• EPA Substance Registry System: 5-(azidomethyl)-3-(4-methoxyphenyl)-1,2,4-oxadiazole(1304081-27-3)

Safety Data

• Hazardous Substances Data: 1304081-27-3(Hazardous Substances Data)

Upstream product

• 57238-76-3 3-(4-methoxyphenyl)-5-(chloromethyl)-1,2,4-oxadiazole 
• 874-90-8 4-methoxybenzonitrile 
• 5373-87-5 4-methoxybenzamidoxime 

Relevant articles and documents

Synthesis of Some Azamacrocycles Bearing 1,2,4-Oxadiazole and 1,2,3-Triazole Moieties

Abstract: A tetraazacrown ether,4,9-di(prop-2-yn-1-yl)-1,4,9,12-tetraazacyclohexadecane-2,11-dione, bearingpropargyl groups on two nitrogens was synthesized starting from1,4,9,12-tetraazacyclohexadecane-2,11-dione and subjected to 1,3-cycloadditionreactio

Design, synthesis, biological evaluation, and docking study of acetylcholinesterase inhibitors: New acridone-1,2,4-oxadiazole-1,2,3-triazole hybrids

In this study, novel acridone-1,2,4-oxadiazole-1,2,3-triazole hybrids were designed, synthesized, and evaluated for their acetylcholinesterase and butyrylcholinesterase inhibitory activity. Among various synthesized compounds, 10-((1-((3-(4-methoxyphenyl)-1,2,4-oxadiazol-5-yl)methyl)-1H-1,2,3-triazol-4-yl)methyl)acridin-9(10H)-one 10b showed the most potent anti-acetylcholinesterase activity (IC50 = 11.55 μm) being as potent as rivastigmine. Also docking outcomes were in good agreement with in vitro results confirming the dual binding inhibitory activity of compound 10b. A novel series of acridone-1,2,4-oxadiazole-1,2,3-triazole hybrids were synthesized and evaluated in vitro for their acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) inhibitory activities.

Synthesis and anti-protozoal activity of novel dihydropyrrolo[3,4-d][1,2,3] triazoles

1,2,4-Oxadiazole and 1,2,3-triazole containing heterocyclic compounds continue to gain interest in synthesis of chemical entities and exhibit various biological activities as anti-protozoal and anti-cancer agents. By using the principle of bioisosterism,