1309922-72-2

Basic information

• Product Name: (3S,5R)-5-((1S,3S)-1-azido-3-(4-methoxy-3-(methoxypropoxy)benzyl)-4-methylpentyl)-3-isopropyl-dihydrofuran-2(3H)-one
• Synonyms: (3S,5R)-5-((1S,3S)-1-azido-3-(4-methoxy-3-(methoxypropoxy)benzyl)-4-methylpentyl)-3-isopropyl-dihydrofuran-2(3H)-one
• CAS NO: 1309922-72-2
• Molecular Weight: 461.602
• Mol File: 1309922-72-2.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (3S,5R)-5-((1S,3S)-1-azido-3-(4-methoxy-3-(methoxypropoxy)benzyl)-4-methylpentyl)-3-isopropyl-dihydrofuran-2(3H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: (3S,5R)-5-((1S,3S)-1-azido-3-(4-methoxy-3-(methoxypropoxy)benzyl)-4-methylpentyl)-3-isopropyl-dihydrofuran-2(3H)-one(1309922-72-2)
• EPA Substance Registry System: (3S,5R)-5-((1S,3S)-1-azido-3-(4-methoxy-3-(methoxypropoxy)benzyl)-4-methylpentyl)-3-isopropyl-dihydrofuran-2(3H)-one(1309922-72-2)

Safety Data

• Hazardous Substances Data: 1309922-72-2(Hazardous Substances Data)

Upstream product

• 69-65-8 mannitol 
• 3969-59-3 mannitol triacetonide 
• 3969-84-4 3,4-di-O-isopropylidene-D-mannitol 
• 166239-53-8 (E)-3-[(4R,5R)-5-((E)-2-Ethoxycarbonyl-vinyl)-2,2-dimethyl-[1,3]dioxolan-4-yl]-acrylic acid ethyl ester 
• 155128-49-7 Diethyl (+)-(4R,5R)-4,5-O-isopropylidene-4,5-dihydroxyoctanedioate 
• 129213-64-5 (R,R')-tetrahydro<2,2'-bifuran>-5,5'(2H,2'H)-dione 
• 1309922-62-0 C₁₄H₂₂O₆ 
• 1309922-63-1 C₁₄H₁₈O₄ 
• 1309922-64-2 (2R,2'R,4R,4'R)-4,4'-diisopropyl-tetrahydro-2,2'-bifuran-5,5'(2H,2'H)-dione 
• 1309922-65-3 (3S,5R)-5-((1R,3S)-1-Hydroxy-3-(4-methoxy-3-(methoxypropoxy)benzoyl)-4-methylpentyl)-3-isopropyl-dihydrofuran-2(3H)-one 
• 1309922-70-0 (3S,5R)-5-((1R,3S)-1-hydroxy-3-(4-methoxy-3-(methoxypropoxy)benzyl)-4-methylpentyl)-3-isopropyl-dihydrofuran-2(3H)-one 
• 1309922-71-1 (1R,3S)-1-((2R,4S)-4-isopropyl-5-oxo-tetrahydrofuran-2-yl)-3-(4-methoxy-3-(methoxypropoxy)benzyl)-4-methylpentyl methanesulfonate 
• 1607844-98-3 C₁₄H₁₈O₄ 
• 148515-21-3 ethyl 2-(diethoxyphosphoryl)-3-methylbutyrate 

Downstream Products

• 173334-57-1 (2S,4S,5S,7S)-5-Amino-4-hydroxy-2-isopropyl-7-[4-methoxy-3-(3-methoxy-propoxy)-benzyl]-8-methyl-nonanoic acid (2-carbamoyl-2-methyl-propyl)-amide 
• 1607844-94-9 (2S,4R,5S,7S)-N-(3-amino-2,2-dimethyl-3-oxopropyl)-5-azido-4-hydroxy-2-isopropyl-7-(4-methoxy-3-(methoxypropoxy)benzyl)-8-methylnonanamide 
• 1607844-95-0 (3S,5R,6S,8S)-3-(3-amino-2,2-dimethyl-3-oxopropylcarbamoyl)-6-azido-8-(4-methoxy-3-(methoxypropoxy)-benzyl)-2,9-dimethyldecan-5-yl methanesulfonate 
• 324763-47-5 (2S,4S,5S,7S)-N-(3-amino-2,2-dimethyl-3-oxopropyl)-5-azido-4-hydroxy-2-isopropyl-7-(4-methoxy-3-(methoxypropoxy)benzyl)-8-methylnonanamide 
• 1206809-73-5 (3S,5R)-5-((1S,3S)-1-amino-3-(4-methoxy-3-(3-methoxypropoxy)benzyl)-4-methylpentyl)-3-isopropyldihydrofuran-2(3H)-one 
• 173338-07-3 tert-butyl (3S,5S,6S,8S)-8-(3-amino-2,2-dimethyl-3-oxopropylcarbamoyl)-6-hydroxy-3-(4-methoxy-3-(3-methoxypropoxy)benzyl)-2,9-dimethyldecan-5-ylcarbamate 

Relevant articles and documents

A aliskiren or its salt separation and analysis method

The invention relates to a separation analysis method using polysaccharide derivative-bonded and coated silica as a stationary phase and an organic solvent as a mobile phase for separation analysis of aliskiren and isomers thereof, effective separation of the aliskiren and isomers thereof can be realized, and the separation analysis method has the important meaning to the product quality control.

A NOVEL PROCESS FOR MAKING ALISKIREN, ITS NOVEL INTERMEDIATES AND CERTAIN NOVEL COMPOUNDS

A novel process for making Renin inhibitors like Aliskiren is disclosed. Its novel intermediate compounds and method of making them are also disclosed.