1315275-20-7

Basic information

• Product Name: 2-(4-methoxyphenethylsulfinyl)-N-methylbenzamide
• Synonyms: 2-(4-methoxyphenethylsulfinyl)-N-methylbenzamide
• CAS NO: 1315275-20-7
• Molecular Weight: 317.409
• Mol File: 1315275-20-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-(4-methoxyphenethylsulfinyl)-N-methylbenzamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-methoxyphenethylsulfinyl)-N-methylbenzamide(1315275-20-7)
• EPA Substance Registry System: 2-(4-methoxyphenethylsulfinyl)-N-methylbenzamide(1315275-20-7)

Safety Data

• Hazardous Substances Data: 1315275-20-7(Hazardous Substances Data)

Upstream product

• 3724-10-5 2-(methylthio)benzoic acid 
• 147-93-3 Thiosalicylic acid 
• 54705-23-6 methyl o-(N-methylcarbamoyl)phenyl sulphoxide 
• 824-94-2 p-methoxybenzyl chloride 
• 52369-55-8 N-methyl-2-(methylsulphinyl)-benzamide 

Relevant articles and documents

An umpolung sulfoxide reagent for use as a functionalized benzyl carbanion equivalent

N-Methyl ortho-carbamoylaryl benzyl sulfoxides can be used as synthetic equivalents for α-hydroxy, α-chloro, and α-acetammido benzyl carbanions by means of a two-step sequence involving highly diastereoselective α-C-alkylation with alkyl halides followed by displacement of the sulfinyl residue (which can be recovered and recycled) by a hydroxyl, a chlorine or an acetamido, respectively, under non-oxidative Pummerer conditions. The scope and limits of the method, including a stereoselective version of the reaction, as well as the mechanism of the process are discussed in detail.