52369-55-8

Basic information

• Product Name: N-methyl-2-(methylsulphinyl)-benzamide
• Synonyms: N-methyl-2-(methylsulphinyl)-benzamide
• CAS NO: 52369-55-8
• Molecular Weight: 181.258
• Mol File: 52369-55-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: N-methyl-2-(methylsulphinyl)-benzamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-methyl-2-(methylsulphinyl)-benzamide(52369-55-8)
• EPA Substance Registry System: N-methyl-2-(methylsulphinyl)-benzamide(52369-55-8)

Safety Data

• Hazardous Substances Data: 52369-55-8(Hazardous Substances Data)

Upstream product

• 147-93-3 Thiosalicylic acid 
• 3724-10-5 2-(methylthio)benzoic acid 
• 74-89-5 methylamine 
• 1442-03-1 2-methylsulfanyl-benzoyl chloride 

Downstream Products

• 52369-07-0 2-methylsulfanyl-thiobenzoic acid methylamide 
• 2527-66-4 2-methyl-1,2-benzisothiazole-3(2H)-one 
• 54705-23-6 methyl o-(N-methylcarbamoyl)phenyl sulphoxide 
• 1315275-20-7 2-(4-methoxyphenethylsulfinyl)-N-methylbenzamide 
• 69977-87-3 Benzoic acid 2-methylcarbamoyl-phenylsulfanylmethyl ester 

Relevant articles and documents

Synthetic method 1-2 - benzisothiazol -3 -one compound (by machine translation)

The invention discloses a synthetic method of 1-2 - benzisothiazol -3 -one compound, and belongs to the field of chemical synthesis. 2 - 1-benzisothiazol 2 -one compounds are synthesized through acid chlorination, amidation and cyclization reaction by using the sulfenyl-substituted benzoic acid extracted from BIT process -3 - waste water as a starting raw material. The method disclosed by the invention has the advantages of mild reaction conditions, simple and convenient operation, strong practicability, less waste water, high product purity and the like, and is suitable for large-scale industrial production. The technical scheme provided by the invention is resource utilization and preparation 1 of wastewater extract produced in BIT production, and a feasible method is provided for the 2 -benzisothiazol -3 -one compound. (by machine translation)

An umpolung sulfoxide reagent as α-hydroxy and α-chloro benzyl carbanion equivalents

ortho-[(N-Methyl)carbamoyl]phenyl benzyl sulfoxide is used as a synthetic equivalent of α-hydroxy and α-chloro benzyl carbanions by means of a two-step sequence involving (1) highly stereoselective α-C-alkylation with alkyl bromides, and (2) displacement of the sulfinyl group by an OH or a Cl under Pummerer or chloro-Pummerer conditions, respectively. The sulfinyl auxiliary can be effectively regenerated and recycled.