1315578-07-4

Basic information

• Product Name: methyl 2-phenylquinazoline-6-carboxylate
• Synonyms: methyl 2-phenylquinazoline-6-carboxylate
• CAS NO: 1315578-07-4
• Molecular Weight: 264.283
• Mol File: 1315578-07-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: methyl 2-phenylquinazoline-6-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 2-phenylquinazoline-6-carboxylate(1315578-07-4)
• EPA Substance Registry System: methyl 2-phenylquinazoline-6-carboxylate(1315578-07-4)

Safety Data

• Hazardous Substances Data: 1315578-07-4(Hazardous Substances Data)

Upstream product

• 100-52-7 benzaldehyde 
• 142031-67-2 methyl 4-bromo-3-(bromomethyl)benzoate 
• 841296-15-9 methyl 4-amino-3-formyl-benzoate 
• 100-46-9 benzylamine 

Relevant articles and documents

Synthesis of quinazolines and tetrahydroquinazolines: Copper-catalyzed tandem reactions of 2-bromobenzyl bromides with aldehydes and aqueous ammonia or amines

An efficient synthesis of diversely substituted quinazolines and 1,2,3,4-tetrahydroquinazolines through copper-catalyzed tandem reactions of the readily available 2-bromobenzyl bromides, aldehydes, and aqueous ammonia or amines has been developed. By using ammonia and simple aliphatic amines as the nitrogen source, the present method provides a versatile and practical protocol for the synthesis of quinazolines and 1,2,3,4-tetrahydroquinazolines. Copper on the beat: An efficient, simple and economical synthesis of diversely substituted quinazolines and 1,2,3,4-tetrahydroquinazolines has been developed through copper-catalyzed tandem reactions of the readily available 2-bromobenzyl bromides, aldehydes, and aqueous ammonia or simple aliphatic amines. Copyright