1334547-23-7

Basic information

• Product Name: 3-amino-6-(2,4-dichlorophenyl)-5-trifluoromethylpyridine-2-carboxylic acid methyl ester
• Synonyms: 3-amino-6-(2,4-dichlorophenyl)-5-trifluoromethylpyridine-2-carboxylic acid methyl ester
• CAS NO: 1334547-23-7
• Molecular Weight: 365.139
• Mol File: 1334547-23-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3-amino-6-(2,4-dichlorophenyl)-5-trifluoromethylpyridine-2-carboxylic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3-amino-6-(2,4-dichlorophenyl)-5-trifluoromethylpyridine-2-carboxylic acid methyl ester(1334547-23-7)
• EPA Substance Registry System: 3-amino-6-(2,4-dichlorophenyl)-5-trifluoromethylpyridine-2-carboxylic acid methyl ester(1334547-23-7)

Safety Data

• Hazardous Substances Data: 1334547-23-7(Hazardous Substances Data)

Upstream product

• 1211515-30-8 3-amino-5-(trifluoromethyl)picolinonitrile 
• 1214336-90-9 3-amino-6-(2,6-difluorophenyl)-5-trifluoromethyl-2-pyridinecarboxylicacid 
• 866775-17-9 3-amino-5-trifluoromethyl-pyridine-2-carboxylic acid methyl ester 
• 866775-16-8 3-nitro-5-trifluoromethyl-pyridine-2-carbonitrile 
• 33252-64-1 3-nitro-5-trifluoromethylpyridin-2-ol 
• 866775-18-0 3-amino-6-bromo-5-trifluoromethyl-pyridine-2-carboxylic acid methyl ester 
• 68716-47-2 2,4-dichlorophenylboronic acid 

Downstream Products

• 1334546-83-6 3-amino-6-(2,4-dichlorophenyl)-5-trifluoromethylpyridine-2-carboxylic acid 

Relevant articles and documents

Pyridine and Pyrazine derivative for the Treatment of CF, COPD, and Bronchiectasis

The present invention provides pyridine and pyrazine derivatives which restore or enhance the function of mutant and/or wild type CFTR to treat bronchiectasis, cystic fibrosis, primary ciliary dyskinesia, chronic bronchitis, chronic obstructive pulmonary disease, asthma, respiratory tract infections, lung carcinoma, xerostomia and keratoconjunctivitis sire, or constipation (IBS, IBD, opioid induced). Pharmaceutical compositions comprising such derivatives are also encompassed.