133600-76-7

Basic information

• Product Name: 3-benzoyl-2-(4-hydroxy-3-methoxyphenyl)thiazolidine
• CAS NO: 133600-76-7
• Molecular Weight: 315.393
• Mol File: 133600-76-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-benzoyl-2-(4-hydroxy-3-methoxyphenyl)thiazolidine(CAS DataBase Reference)
• NIST Chemistry Reference: 3-benzoyl-2-(4-hydroxy-3-methoxyphenyl)thiazolidine(133600-76-7)
• EPA Substance Registry System: 3-benzoyl-2-(4-hydroxy-3-methoxyphenyl)thiazolidine(133600-76-7)

Safety Data

• Hazardous Substances Data: 133600-76-7(Hazardous Substances Data)

Upstream product

• 121-33-5 vanillin 
• 98-88-4 benzoyl chloride 
• 98896-96-9 2-(4-hydroxy-3-methoxyphenyl)thiazolidine 

Downstream Products

• 133600-91-6 [4-(3-Benzoyl-thiazolidin-2-yl)-2-methoxy-phenoxy]-acetic acid ethyl ester 

Relevant articles and documents

Synthesis and evaluation of novel thiazolidine derivatives as thromboxane A2 receptor antagonists

A series of 3-benzoyl or 3-phenylsulfonyl-2-substituted thiazolidine derivatives were synthesized, and evaluated for their thromboxane A2 (TXA2) receptor-antagonizing effect on (15S)-15-hydroxy-11α,9α- (epoxymethano)prosta-5(Z),13(E)-dienoic acid (U-46619)-induced aggregation of rabbit platelet-rich plasma (PRP). A simple 2-arylthiazolidine derivative, 3- benzoyl-2-(4-hydroxy-3-methoxyphenyl)thiazolidine (5a), showed mild TXA2 receptor antagonist activity. Modification of 5a led to 2-chloro-4-[3-(4- chlorophenylsulfonyl)thiazolidin-2-ylmethyl]phenoxyaretic acid (29d), which showed 10 times more potent TXA2 receptor antagonist activity than 5a.