134395-21-4 Usage
Description
5'-Chloro-6'-oxo SiMvastatin is an intermediate compound in the synthesis of Simvastatin analogs. It is a white solid with specific chemical properties that make it a valuable component in the production of related pharmaceuticals.
Used in Pharmaceutical Industry:
5'-Chloro-6'-oxo SiMvastatin is used as an intermediate in the preparation of Simvastatin analogs for the development of medications that can help in managing cholesterol levels and treating related conditions. Its role in the synthesis process is crucial for creating effective and safe pharmaceutical products.
Check Digit Verification of cas no
The CAS Registry Mumber 134395-21-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,4,3,9 and 5 respectively; the second part has 2 digits, 2 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 134395-21:
(8*1)+(7*3)+(6*4)+(5*3)+(4*9)+(3*5)+(2*2)+(1*1)=124
124 % 10 = 4
So 134395-21-4 is a valid CAS Registry Number.
134395-21-4Relevant articles and documents
Synthesis of L-669,262, a Potent HMG-CoA Reductase Inhibitor
Stokker, Gerald E.
, p. 5983 - 5986 (1994)
Synthesis of L-669,262, isosimvastatin-3-one, has been achieved in seven steps from simvastatin (MK-733) and has been shown to be one of the most potent inhibitors of HMG-CoA reductase found to date.The synthesis of the 6-methyl homolog of simvastatin is also described.
