1351416-37-9Relevant articles and documents
Nitrene transfer catalyzed by a non-heme iron enzyme and enhanced by non-native small-molecule ligands
Goldberg, Nathaniel W.,Knight, Anders M.,Zhang, Ruijie K.,Arnold, Frances H.
, p. 19585 - 19588 (2019)
Transition-metal catalysis is a powerful tool for the construction of chemical bonds. Here we show that Pseudomonas savastanoi ethylene-forming enzyme, a non-heme iron enzyme, can catalyze olefin aziridination and nitrene C-H insertion, and that these activities can be improved by directed evolution. The non-heme iron center allows for facile modification of the primary coordination sphere by addition of metal-coordinating molecules, enabling control over enzyme activity and selectivity using small molecules.
Enantioselective intramolecular benzylic C-H bond amination: Efficient synthesis of optically active benzosultams
Ichinose, Masami,Suematsu, Hidehiro,Yasutomi, Yoichi,Nishioka, Yota,Uchida, Tatsuya,Katsuki, Tsutomu
supporting information; experimental part, p. 9884 - 9887 (2011/12/02)
'Salen' along: The iridium(III)-salen complex 1 efficiently catalyzes the title reaction of 2-ethylbenzenesulfonyl azides to give five-membered sultams with high enantioselectivity. Other 2-alkyl-substitued substrates lead to five- and six-membered sultam
