13569-96-5

Basic information

• Product Name: 4-(4-BROMO-PHENYL)-1H-IMIDAZOLE
• Synonyms: 4-(4-BROMO-PHENYL)-1H-IMIDAZOLE;5-(4-Bromophenyl)-3H-imidazole;4-(4-BroMophenyl)iMidazole, 97%
• CAS NO: 13569-96-5
• Molecular Formula: C₉H₇BrN₂
• Molecular Weight: 223.06928
• Mol File: 13569-96-5.mol
• Article Data: 7

Chemical Properties

• Melting Point: 139-143 °C
• Boiling Point: 427°C at 760 mmHg
• Flash Point: 212°C
• Appearance: /
• Density: 1.565g/cm³
• Vapor Pressure: 4.22E-07mmHg at 25°C
• Refractive Index: 1.635
• PKA: 12.92±0.10(Predicted)
• CAS DataBase Reference: 4-(4-BROMO-PHENYL)-1H-IMIDAZOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(4-BROMO-PHENYL)-1H-IMIDAZOLE(13569-96-5)
• EPA Substance Registry System: 4-(4-BROMO-PHENYL)-1H-IMIDAZOLE(13569-96-5)

Safety Data

• Hazard Codes: Xn
• Statements: 22-37/38-41
• Safety Statements: 26-39
• RIDADR: UN 2811 6.1/PG 3
• WGK Germany: 3
• Hazardous Substances Data: 13569-96-5(Hazardous Substances Data)

Usage

General Description

4-(4-Bromo-phenyl)-1H-imidazole, also known as 4-(4-Bromophenyl)imidazole, is a chemical compound with the molecular formula C9H7BrN2. It is a derivative of imidazole and contains a bromine-substituted phenyl group. 4-(4-BROMO-PHENYL)-1H-IMIDAZOLE is commonly used in organic synthesis and pharmaceutical research, having potential applications in the development of pharmaceutical drugs and fine chemicals. Its structure and properties make it a valuable building block for the synthesis of various biologically active compounds and materials. Additionally, 4-(4-Bromo-phenyl)-1H-imidazole has also been studied for its potential applications in the field of medicinal chemistry, where it may exhibit pharmacological activities and therapeutic potential.

InChI:InChI=1/C9H7BrN2/c10-8-3-1-7(2-4-8)9-5-11-6-12-9/h1-6H,(H,11,12)

Upstream product

• 50-00-0 formaldehyd 
• 3343-45-1 4-bromo-2-hydroxyacetophenone 
• 77287-34-4 formamide 
• 99-73-0 para-bromophenacyl bromide 
• 67-56-1 methanol 
• 1021919-40-3 2-(4-bromophenyl)-4-tosyloxazole 
• 1122-91-4 4-bromo-benzaldehyde 

Downstream Products

• 773893-61-1 2-[4-(4-bromophenyl)-1H-imidazol-1-yl]pyridine 
• 1021919-41-4 5-(4-(trimethylstannyl)phenyl)-1H-imidazole 
• 136350-70-4 4-(4-bromophenyl)-1-methyl-1H-imidazole 
• 1609658-41-4 1-(4-benzyloxybenzyl)-4-(4-bromophenyl)-1H-imidazole 

Relevant articles and documents

Preparation of Imidazole Derivatives via Bisfunctionalization of Alkynes Catalyzed by Ruthenium Carbonyl

A one-step, oxidative bisfunctionalization of alkynes to generate cis -enediol diacetates catalyzed by ruthenium carbonyl (triruthenium dodecacarbonyl) is presented. The reaction was performed using the alkyne, (diacetoxyiodo)benzene, Ru 3 (CO) 12 as the catalyst, and toluene as the solvent at 100 °C to give the cis -enediol diacetates in up to 82percent yields. This method overcomes the shortcomings of existing methods, such as tedious reaction steps, substrate limitations, and the use of toxic reagents. Furthermore, the reaction of module cis -enediol diacetates with ammonium carbonate [(NH 4) 2 CO 3 ] in an alcohol solvent gave imidazole derivatives in 37-84percent yields, thus providing a simple and mild new method for the synthesis of imidazole compounds.

IDO inhibitors

Presently provided are compounds according to the formula (I) or (II), and pharmaceutical compositions comprising the compounds, wherein R1, R4, and R5 are defined herein. Such compounds and compositions are useful for mod

IMIDAZOLE DERIVATIVES USEFUL AS MODULATORS OF FAAH AND AS FAAH IMAGING AGENTS

The present invention is directed to certain Inidazole derivatives which are useful as modulators of Fatty Acid Amide Hydrolase (FAAH) and as FAAH imaging agents. The invention is also concerned with pharmaceutical formulations comprising these compounds