135829-05-9

Basic information

• Product Name: N-(benzyloxycarbonyl)indoline-2-carbaldehyde
• Synonyms: N-(benzyloxycarbonyl)indoline-2-carbaldehyde
• CAS NO: 135829-05-9
• Molecular Weight: 281.311
• Mol File: 135829-05-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: N-(benzyloxycarbonyl)indoline-2-carbaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: N-(benzyloxycarbonyl)indoline-2-carbaldehyde(135829-05-9)
• EPA Substance Registry System: N-(benzyloxycarbonyl)indoline-2-carbaldehyde(135829-05-9)

Safety Data

• Hazardous Substances Data: 135829-05-9(Hazardous Substances Data)

Upstream product

• 135829-04-8 benzyl 2-(Hydroxymethyl)-1-indolinecarboxylate 
• 16851-56-2 indolin-2-yl carboxylic acid 
• 135829-03-7 methyl (+/-)-1-benzyloxycarbonyl-indoline-2-carboxylate 
• 79-37-8 oxalyl dichloride 
• 497-19-8 sodium carbonate 
• 501-53-1 benzyl chloroformate 
• 3770-50-1 2-carbethoxyindole 
• 210364-11-7 2,3-Dihydro-indole-1,2-dicarboxylic acid 1-benzyl ester 2-ethyl ester 

Relevant articles and documents

Aldolase-catalyzed synthesis of conformationally constrained iminocyclitols: Preparation of polyhydroxylated benzopyrrolizidines and cyclohexapyrrolizidines

A straightforward chemo-enzymatic synthesis of new polyhydroxylated benzopyrrolizidines and cyclohexapyrrolizidines is developed. The two-step strategy consists of l-fuculose-1-phosphate aldolase variant F131A-catalyzed aldol addition of dihydroxyacetone phosphate to rac-N-benzyloxycarbonylindoline- 2-carbaldehyde as well as (2S*,3aS*,7aS*)- and (2S*,3aR*,7aR*)-N-benzyloxycarbonyloctahydroindole-2- carbaldehydes and a subsequent one-step catalytic deprotection-reductive amination.

Tricyclic [6.5.51]-fused oxazolidinone antibacterial agents

The present invention involves tricyclic-fused 6-member ring oxazolidinones STR1 and tricyclic-fused 5-member ring oxazolidinones STR2 which are useful as antibacterial agents.