1365267-36-2 Usage
Description
1,2-BenzenedicarboxaMide, N1,N2-bis[[(5S)-2-oxo-3-[4-(3-oxo-4-Morpholinyl)phenyl]-5-oxazolidinyl]Methyl]is a complex organic compound with a unique molecular structure. It is characterized by its benzene core with two carboxamide groups attached to the 1 and 2 positions, and a bis-oxazolidinylmethyl group connected to the nitrogen atoms of the carboxamides. 1,2-BenzenedicarboxaMide, N1,N2-bis[[(5S)-2-oxo-3-[4-(3-oxo-4-Morpholinyl)phenyl]-5-oxazolidinyl]Methyl]exhibits a high level of structural complexity and has potential applications in various fields due to its unique properties.
Uses
Used in Pharmaceutical Industry:
1,2-BenzenedicarboxaMide, N1,N2-bis[[(5S)-2-oxo-3-[4-(3-oxo-4-Morpholinyl)phenyl]-5-oxazolidinyl]Methyl]is used as an impurity in the synthesis of Rivaroxaban (R538000), a novel antithrombotic agent. Rivaroxaban is a highly potent and selective, direct FXa inhibitor, which makes it an important compound in the development of new antithrombotic drugs. The presence of this compound as an impurity can affect the purity and efficacy of the final drug product, making its study and control crucial in the pharmaceutical industry.
Used in Research and Development:
Due to its complex structure and potential interactions with biological systems, 1,2-BenzenedicarboxaMide, N1,N2-bis[[(5S)-2-oxo-3-[4-(3-oxo-4-Morpholinyl)phenyl]-5-oxazolidinyl]Methyl]can be used as a research compound in various scientific fields. It may be studied for its potential applications in drug design, chemical synthesis, and material science, among others. Researchers can explore its properties, reactivity, and interactions with other molecules to gain insights into its potential uses and applications.
Used in Quality Control and Analysis:
The presence of 1,2-BenzenedicarboxaMide, N1,N2-bis[[(5S)-2-oxo-3-[4-(3-oxo-4-Morpholinyl)phenyl]-5-oxazolidinyl]Methyl]as an impurity in the synthesis of Rivaroxaban necessitates its analysis and control in the final drug product. Quality control and analytical methods, such as high-performance liquid chromatography (HPLC), mass spectrometry, and nuclear magnetic resonance (NMR) spectroscopy, can be employed to detect and quantify this compound in pharmaceutical formulations. This ensures the safety, efficacy, and quality of the final drug product.
Check Digit Verification of cas no
The CAS Registry Mumber 1365267-36-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,6,5,2,6 and 7 respectively; the second part has 2 digits, 3 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1365267-36:
(9*1)+(8*3)+(7*6)+(6*5)+(5*2)+(4*6)+(3*7)+(2*3)+(1*6)=172
172 % 10 = 2
So 1365267-36-2 is a valid CAS Registry Number.
1365267-36-2Relevant articles and documents
PROCESS FOR DETERMINING THE SUITABILITY FOR DISTRIBUTION OF A BATCH OF A THIOPHENE-2-CARBOXAMIDE DERIVATIVE
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Page/Page column 33-34, (2012/04/04)
The present invention relates to a process for determining the suitability for distribution of a batch of rivaroxaban or of a pharmaceutical composition thereof. In particular, it also relates to two impurities of rivaroxaban, to their use as reference markers to determine the purity of a sample of rivaroxaban or a composition thereof, to analytical methods for determining the purity of a sample of rivaroxaban or a composition thereof and to a process of preparing rivaroxaban or pharmaceutical compositions thereof which are free or substantially free of such impurities.
